QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.

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Found 123 matching student topics

Displaying 49–60 of 123 results

Interaction between pollen proteases and ACE2 receptor of SARS-CoV-2

Pollen allergy is a common seasonal respiratory disease triggered by hypersensitivity to pollen affecting 10-30% of adults and 40% of children, and is a predisposing factor for asthma. Pollens interact with airway epithelium to both stimulate innate immunity and elicit an adaptive immune response.Proteolytic activity is one route that stimulates release of alarmins and pro-inflammatory cytokines from mucosal epithelia. Previous studies have found the expression of Serine/Cysteine (Ser/Cys) proteases in some types of grass pollen grains, but it is not …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

Why do epithelial cells have antigen processing machinery?

Epithelial Cells (ECs) constitute the border between the host immune system and an environment teeming with inhaled antigens. Work from us and others has highlighted that ECs have the ability to express the antigen processing and presentation machinery, Major Histocompatibility Complex class II (MHC II) that is important in initiating immune responses. MHC II expression and function on mucosal epithelial cells, is not well understood.Whilst MHC II is expressed by ECs, and is altered with inflammation, there is a paucity …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

Exploring chemotherapy-induced molecular aging and its relationship to exercise

Ovarian cancer is the sixth most common cause of death from cancer in women, with a five-year survival rate of less than 45 per cent. However, there is emerging research that shows the benefits of exercise therapy during recovery following certain cancer treatments, and how exercise can improve and extend the lives of women with ovarian cancer.This project is a collaboration exploring these health and survival outcomes in ovarian and other gynaecological cancers, and in particular how new diagnostic testing …

Study level
Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

Understanding capsular polysaccharide diversity is key to next generation therapies for multi-drug resistant Acinetobacter baumannii infections

Bacteriophage therapy is an attractive innovative treatment for infections caused by extensively drug resistant Acinetobacter baumannii, for which there are few effective antibiotic treatments remaining.Capsular polysaccharide (CPS) is a primary receptor for lytic bacteriophage, thus knowledge of the chemical structures of CPS produced by the species underpins the identification of suitable phage for therapeutic cocktails.As many phage depolymerases cleave a specific CPS linkage formed by either a glycosyltransferase or polymerase enzyme, characterisation of these proteins are essential.However, these remain largely …

Study level
PhD
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)

Centre for Immunology and Infection Control

Human Emotional Learning: Likes, Dislikes and Fear

There is currently broad agreement that likes and dislikes, including strong emotional responses such as fear and anxiety, are learned. However, little is known about the manner in which different forms of emotional learning interact or about how emotional learning once acquired can be modified, reduced or eliminated. In particular in the context of fear learning this is problematic as fear memories once acquired seem difficult to change and likely to return even after successful extinction – a phenomenon known …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Psychology and Counselling

The Emotional Face

Faces are a rich source of social information communicating social categories like sex, age or ethnicity of a person, but also a person’s emotional state via facial expressions of emotion. The current research investigates how cues available on a face (social category cues, attractiveness, trustworthiness) or what we know about a person affect the manner in which we process emotional expressions.

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Psychology and Counselling

Understanding how self-image and compassionate goals affect well-being in a social media context

There is increasing concern about the negative impact of social media use on well-being. To understand its impact, we need to move beyond simple conceptualisations of social media use and utilise strong research methods to understand the role that psychological processes play in producing positive and negative impacts. There is preliminary evidence that interpersonal goals play an important role in predicting how people use and experience social media. Self-image goals involve trying to convey a desirable image of oneself to …

Study level
PhD
Faculty
Faculty of Health
School
School of Psychology and Counselling

TRAP: Translation into practice of tools for risk assessment for healing and prevention of venous leg ulcers

Approximately 30% of venous leg ulcers (VLUs) fail to respond to evidence-based treatments and remain unhealed; while after healing, 60–70% of ulcers recur. Currently most clinicians use only their experience to identify patients with VLUs at high risk of failure to heal or recurrence after healing.To address this problem objectively, this project team has developed and validated two risk assessment tools to identify patients at high risk of failure to heal or ulcer recurrence. A prospective, multi-site study has demonstrated …

Study level
PhD
Faculty
Faculty of Health
School
School of Nursing

Identifying disease distress in patients with chronic venous leg ulcers

Venous leg ulcers (VLUs) make up 70% of all chronic leg ulcers. Unfortunately, around 30% of VLUs fail to heal in a 24-week period often despite evidence-based practice. Chronic VLUs impose a significant burden on people with these ulcers. Disease related distress has been explored in diabetes and inflammatory bowel disease but has not been explored in chronic wounds.Research has completed phase one of this study (secondary analysis of existing data), phase two (focus group to explore the findings), phase …

Study level
Master of Philosophy
Faculty
Faculty of Health
School
School of Nursing

Wound care in people with dementia: the silent unknown

The incidence of both dementia and chronic wounds increases with age, thus, given the ageing population, the overlap is strong.Clinicians report managing wounds in adults with dementia is a frequent and challenging problem, yet people with dementia are generally excluded from research into evidence-based wound care despite impaired cognition, high incidence of falls, immobility and incontinence, all of which are recognised risk factors for skin tears and chronic wounds.This project aims to investigate the evidence in regard to dementia and …

Study level
PhD, Master of Philosophy
Faculty
Faculty of Health
School
School of Nursing

Wound care in regional/rural Queensland

Barriers to health care for regional/rural residents often relate to the limited availability of local health services and resources and the distance needed to seek suitable specialised services. Wounds experienced in rural and regional areas are often dependent upon the types of employment available, recreational pursuits and risk-taking behaviours.The prevalence of non-communicable lifestyle related risk factors (such as obesity and poor nutrition) and the propensity for an ageing population in rural and regional areas, positions this population group as one …

Study level
PhD, Master of Philosophy
Faculty
Faculty of Health
School
School of Nursing

Engineering bioartificial extracellular tumour microenvironments for Osteosarcoma personalised precision oncology

Osteosarcoma (OS) is the most common malignant bone tumour affecting children and adolescents. Importantly, clinical outcomes have not improved for decades, and bone tumours remain to be a leading cause of cancer-related death in adolescents.By identifying ideal treatment approaches for each individual patient, precision oncology has the potential to significantly improve these outcomes. Yet, its widespread application is hindered by a lack of biomaterials that support the reproducible and robust generation of patient-derived osteosarcoma organoids in vitro.Therefore, this project will …

Study level
PhD, Master of Philosophy
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)
Centre for Biomedical Technologies

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