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Enhancing wellbeing of youth from culturally diverse and refugee backgrounds

Australia has a multicultural population, with approximately 30% of the population from diverse backgrounds. We will propose a program of research encompassing the development of assessment processes and also interventions, addressing the diverse needs of this population, Proposed research will build upon work already undertaken by the team in collaboration with Education Queensland including Milpera State School. Methodologies to date have been broadly based, including both quantitative and qualitative approaches. These have included the examination of psychometric properties of scales …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Psychology and Counselling
Research centre(s)

Australian Centre for Philanthropy and Nonprofit Studies

A preclinical evaluation pipeline for new antivirulence drugs targeting multidrug resistant bacterial pathogens

A post-antibiotic era—in which common infections and minor injuries can kill—far from being an apocalyptic fantasy, is instead a very real possibility for the 21st century.’ - WHO, 2014 (1). Antimicrobial resistance (AMR) is a global public health priority. If no action is taken, AMR is predicted to kill more people than cancer and diabetes combined by 2050, with 10 million deaths estimated each year and a global cost of up to 100 trillion USD. New therapies to tackle multidrug …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)

Multi-microbial 3D printing for screening microbiome functions

The ability to 3D print bacteria has relevance to a wide range of applications, ranging from developing novel anti-microbial modalities to probiotics for promoting human health. Traditional culture techniques used in microbiology such as agar plates and suspension cultures have limited spatio-temporal control over the bacteria microenvironment as well as their interaction partners, in particular, mammalian host cells. This project aims to bridge this technological gap by combining 3D printing and microfluidics technologies to spatially control the localisation of multiple …

Study level
PhD, Master of Philosophy
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)

Adaptive evolution of anaerobic methanotrophic (ANME) archaea mediating methane oxidation in freshwater environments (PhD)

The as-yet-uncultured archaeal lineage Methanoperedenaceae are anaerobic methanotrophs with a key role in mitigating the atmospheric release of methane in freshwater environments. The metabolic diversity of these microorganisms directly links methane with several key biochemical cycles and suggests a remarkable ability of these microorganisms to adapt to diverse environmental conditions.The overall aim of this PhD project will be to uncover the metabolic diversity of the Methanoperedenaceae and to understand the evolutionary mechanisms responsible for these adaptations.Methods and ResourcesThe project will …

Study level
PhD
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)

Illuminating the microbial world using genome-based fluorescence microscopy

Our understanding of microbial diversity on Earth has been fundamentally changed by metagenomic characterisation of natural ecosystems. Traditional approaches for visualising microbial communities are time-consuming and provide limited information about the identity of specific microorganisms.The proposed research aims to combine single cell genomics and super resolution microscopy for novel, high-throughput, genome-based techniques to visualise microorganisms, plasmids and viruses, with strain level specificity. The application of these highly scalable approaches will provide comprehensive and unprecedented insight into the fine-scale dynamics and …

Study level
PhD
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)

Food literacy projects (see description for options)

Food Literacy is a collection of knowledge, skills and behaviours required to plan, manage, select, prepare and eat foods to meet needs and determine food intake. It is the scaffolding that empowers individuals, households, communities or nations to protect diet quality through change and strengthen dietary resilience over time. Areas for further research include, but are not limited to:identifying models to integrated food literacy into dietetic practice e.g. through the Nutrition Care Processdevelop population level indicators for food literacy that …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Exercise and Nutrition Sciences
Research centre(s)

Food literacy and children

The term food literacy has been empirically for adults, but not for children. It is likely that the definition would differ for children (including adolescents). Possible research projects in this area include but are not limited to:investigating children's role in feeding themselves, in particular the variables that impact on this; and diet quality and food choice pathways that children use, the impact of economic disadvantage, culture, gender, age, geographydefining and conceptualising food literacy for childrenconceptualising food literacy by those developing …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Exercise and Nutrition Sciences
Research centre(s)

Community and Public Health Nutrition Workforce

The training of a specialised community and public health nutrition (CPHN) workforce assumes they are optimally placed to address food and nutrition issues at a population and community level. However, concomitant with the rise of diet as the leading risk factor contributing to the burden of disease in Australia, has been a dramatic disinvestment in this workforcePermanent, full time nutritionist positions embedded in communities or population settings are few. If an organisation invests in a nutrition intervention it is increasingly …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Exercise and Nutrition Sciences
Research centre(s)

Aboriginal and Torres Strait Islander food and nutrition projects

Aboriginal and Torres Strait Islander peoples suffer disproportionally from diet-related conditions in Australia. Much current research is deficit based, however this body of work aims to be strengths based. Research projects could include, but are not limited to:a descriptive/explorative of food literacy among Aboriginal and Torres Strait Islander people using an assets based framework exploring positive deviants.a food sovereignty project to describe Aboriginal and Torres Strait Islander foodways. This could be applied to a particular nation group. It could be …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Exercise and Nutrition Sciences
Research centre(s)

Using a natural β-carboline dimer compound to target metabolic vulnerabilities linked to glycolysis in prostate cancer

Prostate cancer is an androgen dependent cancer and treatments are aimed at preventing activation of the androgen receptor. Part of the development of resistance to therapies involves prostate cancers reprogramming their metabolism to overcome metabolic stress induced by these therapies and support growth and survival. This reprogramming involves increases in the rate of glycolysis and intermediate pathways branching from glycolysis. Previously in our laboratory, the natural compound, beta-carboline dimer, BD, was identified to have potent effects on cell viability, cell …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)

Characterisation of emerging multidrug resistant E. coli pathogens

The last fifteen years have witnessed an unprecedented rise in the rates of antimicrobial resistance among Gram-negative bacteria, described by the World Health organisation as a global health crisis (1). Escherichia coli sequence type 131 (E. coli ST131) is a ‘high-risk’ group of Gram-negative pathogens that have emerged rapidly and spread worldwide in the period of the last 10 years (2). E. coli ST131 strains are typically resistant to multiple classes of antibiotics and cause bloodstream and urinary tract infections …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)

Identification and functional characterisation of genetic modifiers of iron overload

Iron is an element essential for virtually all life forms; aberrant iron metabolism is linked to many diseases. These include cancers, neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease, iron overload and iron deficiency disorders, iron-loading anaemias, and the anaemia associated with chronic disease. Central to proper iron regulation is the appropriate expression and activity of the liver-expressed regulatory peptide, hepcidin, and the iron exporter, ferroportin (FPN). Modulating the expression and activity of hepcidin and FPN, and their interaction is …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)

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