QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 106 matching student topics
Displaying 85–96 of 106 results
Estimating the evolutionary history of plasmids and viruses
In the case of cellular life - bacteria, archaea and eukaryotes - determining the 'tree of life' is a comparatively well-studied problem.This vertical evolutionary history can be estimated using concatenated gene phylogenies, where single copy marker genes are concatenated into a single multiple sequence alignment which is then used in a phylogenetic tree reconstruction algorithm.Viral genomes and plasmid sequences, meanwhile, are more challenging to fit into a phylogenetic framework.
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
-
Centre for Microbiome Research
NHMRC Idea Grant: intergenerational living and learning models
This research project acts upon recommendations from the Inquiry into the Quality of Care and Residential Aged Care in Australia IQCRAC (2018) by developing an inter-generational model for senior living within school campuses in consultation with industry partners. The project differs from existing programs by establishing an economic policy-driven 'shared campus facilities and services' approach which is person-centred, health focused and socially inclusive. The model intends to be translatable across diverse Australian contexts, from urban realms where land is limited, …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Creative Industries, Education and Social Justice
- School
- School of Design
- Research centre(s)
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Design Lab
CGPH01 - Human neural stem cell models to understand neurogenesis and neurodegeneration
Neurodegenerative disorders such as Alzheimer’s Disease continue to impact the quality of life of a significant number of Australians, yet they remain untreatable. If we focus on how human neural stem cells behave normally and compare them to similar cells from Alzheimer’s patients, we will likely gain a better understanding of what has gone wrong and potentially how to stop it or fix it.
- Study level
- PhD, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Genomics and Personalised Health
The softer side of next-gen entrepreneurship: the emotional experience and success
Next-generation (next-gen) entrepreneurs are described as people who operate solely in online environments (i.e. via the internet). The internet and mobile technologies have profoundly impacted the ways in which business is conducted, yet little is known about this new type of business environment. There has been considerable research into entrepreneurs who operate largely in physical 'bricks and mortar' settings, however the literature is limited in providing insight into entrepreneurs who operate solely in online environments.We know that emotions influence the …
- Study level
- PhD, Master of Philosophy
- School
- null
- Research centre(s)
- null
null
Dissecting the molecular and cellular basis of melanoma susceptibility
Several factors strongly influence an individual’s chance of developing melanoma. Paramount amongst these are the number of moles (nevi) present on the skin, cumulative levels of UV exposure and skin pigmentation phenotype. Numerous Genome Wide Association Studies (GWAS) we have identified gene variants at a number of loci that are strongly associated with cutaneous nevi (mole) counts, UV damage response and accordingly susceptibility of individuals to develop melanoma. Currently the functional impact of genetic variants in the genes IRF4, PLA2G6 …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Next-generation traffic signals for Safe, Efficient and Green Intersections
There is a full PhD scholarship available in the School of Civil and Environmental Engineering at Queensland University of Technology (QUT) to support the newly awarded ARC Linkage Project on Next-generation traffic signals using artificial intelligence-based video analytics for safe, efficient and green intersections. The stipend has a cash value of $32,500 per annum for 3 years.To apply for this position, please submit the following documents via email to m1.haque@qut.edu.au:a detailed curriculum vitae (CV) highlighting academic achievements, research experience and …
- Study level
- PhD
- School
- School of Civil and Environmental Engineering
Characterising drivers of melanoma cell heterogeneity
Tumour cell heterogeneity is linked to tumour progression through the generation of divergent cellular behaviours such as proliferation, survival, invasion and therapy resistance. Crucially, conventional and targeted therapies generally only target highly proliferative cells in tumours leading to initial tumour regression, however alternative sub-populations underpin the return of treatment refractory disease and facilitate metastatic spread. Our laboratory is focused on understanding the regulatory drivers of cellular plasticity in melanoma to better understand progression and metastatic spread of this disease and …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Renewal and differentiation in human neural stem cells and their application to understanding neurological disorders
The effective regeneration of brain tissue requires an understanding of the factors mediating the damage as well as the integration of new/replacement cells to form new functional neural networks. The isolation and expansion of human stem cells and limited neural lineage differentiation have provided the foundation for strategies in the treatment of neurodegenerative disorders. We utilise iPSC-derived NPCs and patient-derived (Alzheimer’s disease; AD) iPSCs and neural lineage differentiation of hMSCs, iPSC NPCs and AD iPSCs in neuronal and glial culture …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
HoliCOW – A holobiont strategy to decipher core host-microbiota interactions in cows
To meet the goal of limiting global warming to 1.5C, methane emissions from ruminants such as beef and dairy cattle must be reduced by 11–30% by 2030 and by 24–47% by 2050 compared to 2010 levels. A newly funded Future Fellowship project is hiring 2 PhD students who will tackle this challenge by creating a thorough mechanistic understanding of the microbiological, biochemical and genetic processes that cause methanogenesis in the cow rumen. These activities will identify core beneficial microbiota that …
- Study level
- PhD
- School
- School of Biomedical Sciences
- Research centre(s)
-
Centre for Microbiome Research
Identifying individuals at high risk of Alzheimer’s disease
Dementia is the greatest cause of disability in Australians over the age of 65 years. In the absence of a significant medical breakthrough, more than $6.4 million Australians will be diagnosed with dementia in the next 40 years. The most common form of dementia is Alzheimer’s disease (AD), accounting for 60-80% of cases. The pathogenic process of AD begins decades prior to the clinical onset, so it is likely that treatments need to begin early in the disease process to …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Understanding the genetics of melanoma susceptibility: many roads lead to DNA repair
Repair of the damage caused by mutagens such as UV and reactive oxygen species is vital to prevent cancer and premature aging and accordingly cells have developed a suite of intricate and specific DNA repair pathways. Loss or abnormal function of components of these pathways lead to cancer pre-disposition syndromes for example breast cancer in individuals carrying mutations in the BRCA1 or BRCA2 genes. Understanding the complexities of these DNA repair pathways is vital to efforts aimed at preventing or …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Development of a multiplexed gut micro-bioreactor for functional screening of gut microbiome
The human microbiome refers to the collection of micro-organisms that are living symbiotically in the human body (defined as the “microbiota”), their genetic material as well as the surrounding environmental habitat.It is now appreciated that the microbiome plays an important role in human health and diseases. Various disease states have been linked to dysregulation of the gut microbiota, including neurodegenerative, cardiovascular and metabolic diseases. The composition of the gut microbiome can also affect responses to therapies, most notably in cancer …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
- Centre for Biomedical Technologies
Centre for Microbiome Research
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