QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 37 matching student topics
Displaying 25–36 of 37 results
TRAP: Translation into practice of tools for risk assessment for healing and prevention of venous leg ulcers
Approximately 30% of venous leg ulcers (VLUs) fail to respond to evidence-based treatments and remain unhealed; while after healing, 60–70% of ulcers recur. Currently most clinicians use only their experience to identify patients with VLUs at high risk of failure to heal or recurrence after healing.To address this problem objectively, this project team has developed and validated two risk assessment tools to identify patients at high risk of failure to heal or ulcer recurrence. A prospective, multi-site study has demonstrated …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Nursing
Identifying disease distress in patients with chronic venous leg ulcers
Venous leg ulcers (VLUs) make up 70% of all chronic leg ulcers. Unfortunately, around 30% of VLUs fail to heal in a 24-week period often despite evidence-based practice. Chronic VLUs impose a significant burden on people with these ulcers. Disease related distress has been explored in diabetes and inflammatory bowel disease but has not been explored in chronic wounds.Research has completed phase one of this study (secondary analysis of existing data), phase two (focus group to explore the findings), phase …
- Study level
- Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Nursing
Wound care in people with dementia: the silent unknown
The incidence of both dementia and chronic wounds increases with age, thus, given the ageing population, the overlap is strong.Clinicians report managing wounds in adults with dementia is a frequent and challenging problem, yet people with dementia are generally excluded from research into evidence-based wound care despite impaired cognition, high incidence of falls, immobility and incontinence, all of which are recognised risk factors for skin tears and chronic wounds.This project aims to investigate the evidence in regard to dementia and …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Nursing
Development of a 3D Printed Nasal Model to Study Viral-Airway Interactions
As airway infections become pandemic worldwide, airway models to investigate pathogen infection mechanism and nasal drug delivery is now increasingly important. However, current airway models cannot mimic the triad coupling of human nasal anatomical geometries, aerosol flow and biological responses (e.g. infection and inflammation) from the nasal epithelium.Computational fluid dynamics (CFD) models are used for simulating pathological airflow patterns resulting from anatomical structural changes of the nasal cavities, but they cannot measure phenotypic or functional alterations in the nasal epithelium …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
- Centre for Biomedical Technologies
A preclinical evaluation pipeline for new antivirulence drugs targeting multidrug resistant bacterial pathogens
A post-antibiotic era—in which common infections and minor injuries can kill—far from being an apocalyptic fantasy, is instead a very real possibility for the 21st century.’ - WHO, 2014 (1). Antimicrobial resistance (AMR) is a global public health priority. If no action is taken, AMR is predicted to kill more people than cancer and diabetes combined by 2050, with 10 million deaths estimated each year and a global cost of up to 100 trillion USD. New therapies to tackle multidrug …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Characterisation of emerging multidrug resistant E. coli pathogens
The last fifteen years have witnessed an unprecedented rise in the rates of antimicrobial resistance among Gram-negative bacteria, described by the World Health organisation as a global health crisis (1). Escherichia coli sequence type 131 (E. coli ST131) is a ‘high-risk’ group of Gram-negative pathogens that have emerged rapidly and spread worldwide in the period of the last 10 years (2). E. coli ST131 strains are typically resistant to multiple classes of antibiotics and cause bloodstream and urinary tract infections …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Legal Approaches to Conservation Conflicts and Land-Use Conflicts
Conservation and land-use conflicts arise when people have different needs and interests concerning a protected area or land space. The management of these types of conflicts often has to broach disciplinary divides to ensure that appropriate consideration is given to the many complex and diverse issues that surround them, such as social justice, food production, biodiversity, the history of a place, and the attitudes and values of local stakeholders. The Law School invites students to express an interest in research …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Business and Law
- School
- School of Law
An airway chip for screening viral infection mediated immune responses
Respiratory infections such as influenza, SARS-COV-2, COVID-19, and MERS are increasingly prevalent. Complications and related deaths arising from these infections are often the result of a “cytokine storm”, whereby there is an over production of proinflammatory soluble factors by immune cells, which dictates symptoms severity and mortality risk. Recent works showed that immunomodulatory therapy, with or without antiviral agents, may improve recovery outcome. However, the screening of suitable immune-modulatory and antiviral agents relies heavily on animal models which can't capture …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
Traces of zinc and ciprofloxacin loaded polymer nanoparticulate inhaled formulations against lung infections associated with COPD and CF (CLIN08)
Lower respiratory tract infections (LRTIs) are one of the fatal diseases of the lungs that have severe impacts on public health, especially for Indigenous people. The currently available antibiotics administered orally for the treatment of LRTIs need high doses with frequent administration and cause dose-related adverse effects. To overcome this problem, we will investigate the development of ciprofloxacin (CIP) loaded poly(2-ethyl-2-oxazoline) (PEtOx) nanoparticles (NPs) with traces of zinc for potential pulmonary delivery from dry powder inhaler (DPI) formulations. As zinc …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Clinical Sciences
- Research centre(s)
-
Centre for Immunology and Infection Control
Biological and clinical impact of the association of germline variations in KLK3 (PSA) gene in prostate cancer
Prostate cancer is the most frequently occurring cancer (after skin cancers) in Australian males, and the second most common cause of cancer death. While the 5-year survival rate for localised disease approaches 100%, extra-prostatic invasion results in a poorer prognosis. Kallikreins are serine proteases, which are part of an enzymatic cascade pathway activated in prostate cancer (Lawrence et al 2010). The most well-known member is prostate specific antigen (PSA) or the KLK3 protein, encoded by the Kallikrein 3 (KLK3) gene, …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Comprehensive strain-level characterisation of microbial communities associated with inflammatory bowel disease
Inflammatory bowel disease (IBD) is a chronic, relapsing inflammatory disorder driven by complex interactions between environmental, microbial and immune-mediated factors 1,2. An unfavourable shift in gut microbiome composition, known as dysbiosis, is now considered a key feature of IBD 2-5, however it is unclear how specific microorganisms and their interactions with host cells contribute to disease onset and progression.Previous IBD studies have been largely limited to older sequencing methods with low phylogenetic and functional resolution. Furthermore, these studies have predominantly …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
-
Centre for Microbiome Research
Strain-level characterisation and visualisation of microbial communities associated with inflammatory bowel disease
Inflammatory bowel disease (IBD) is a chronic, relapsing inflammatory disorder driven by complex interactions between environmental, microbial and immune-mediated factors. An unfavourable shift in gut microbiome composition, known as dysbiosis, is now considered a key feature of IBD, however it is unclear how specific microorganisms and their interactions with host cells contribute to disease onset and progression. Previous IBD studies have been largely limited to older sequencing methods with low resolution. Furthermore, these studies have predominantly focused on bacterial populations, …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
-
Centre for Microbiome Research
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