QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 714 matching student topics
Displaying 13–24 of 714 results
Investigating differences in downstream signalling mediated by two isoforms of FGFR2 in endometrial cancer
FGFR2 encodes two alternatively spliced isoforms that differ in their ligand binding domain and the combination of tissue specific expression of these isoforms and tissue specific expression of the FGF ligands is the foundation of normal paracrine signalling. Isoform switching from FGFR2b (inclusion of exon 8) to FGFR2c (inclusion of exon 9) occurs in tumorigenesis as it establishes an autocrine loop in epithelial cancer cells.We have previously published a detailed investigation into differences between wildtype FGFR2b and mutant FGFR2b following …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Metagenomic analysis of bacterial contamination screening pooled platelets
Bacterial sepsis is second only to ABO incompatibility as a cause of death from transfusion. Bacterial contamination of platelets is recognised as the most significant residual infectious risk of transfusion in developed countries. Bacterial Contamination Screening (BCS) has been required for testing of pooled and apheresis platelets manufactured by the Blood Service since April 2008. International microbiological culture studies suggest that the incidence of bacterial contamination ranges from 1:3000 to 1:1000 units of apheresis platelets and 1 in 600 to …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Determining the theapeutic efficiency of epigenetic drugs in ovarian cancer
Because cancer and many diseases arise from a combination of genetic propensity and the response of cells to external factors mediated through changes to the expression of key genes, it is important to understand epigenetic regulation. The epigenome is crucial to the changes of gene expression and there is now strong evidence that epigenetic alterations are key drivers of cancer progression. However, very few drugs targeting epigenetic modifiers have been successful, in part due to the lack of effective means …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Nutrition interventions to improve outcomes in people with kidney dIsease
Dietary interventions are cornerstone treatment in chronic kidney disease. Our research focuses on the shift away from nutrient monitoring, and towards a whole food approach to improving diet quality and reduce disease progression. We have expertise in nutritional epidemiology and dietary intervention trials, and work directly with clinicians in patient care.We currently have projects investigating:Plant based diets to reduce resistant proteinuriaIntensive weight loss to slow progression of kidney diseaseThe impact of dietary patterns on cardiovascular disease risk in chronic kidney …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Exercise and Nutrition Sciences
Paediatric intensive care survivorship
One in 500 children require admission to paediatric intensive care (PICU) for acute life-threatening illness or injury during their childhood1. There are an estimated 300,000 survivors of paediatric critical illness in Australia. Up to 30% of PICU survivors experience long-term impairments in physical, cognitive, emotional, and social health. This is termed Post Intensive Care Syndrome – Paediatrics, and significantly impacts child development, with a multiplier effect on the family and society. This is believed to be caused, in part, by …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Nursing
- Research centre(s)
- Centre for Healthcare Transformation
Big data analysis to aid ecological research
We're looking for multiple students to help us answer the question: 'How can we utilise information technology to aid ecological research?'Sensor networks bring ecologists and pattern recognition researchers together to make some applications possible. These applications include assessing risks from potential bird collisions, unobtrusive observations (where the presence of humans changes some animal behaviours) and studying spatial and temporal variation in biological processes.With a significant amount of data being collected from these applications, processing and mining this data is challenging. …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Computer Science
Human data interaction with big data visual analytics
Our research is seeking to answer the question: 'How can we support human interaction with big data?'We want to integrate the outstanding capabilities of humans in terms of visual information exploration with the enormous processing power of computers. These elements have the capacity to form a powerful knowledge discovery environment. This research will use datasets from the Queensland Government and the QUT Ecoacoustic research group over multiple years. Other big datasets, such as Amazon’s product review dataset, could also be …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Computer Science
Optimising sampling design for model discrimination of coral reef recovery
Natural disturbances including severe storms and bleaching events have devastating impacts on the Great Barrier Reef's health. Unfortunately, the increasing pressures associated with climate change are causing these disturbances to occur more frequently, for a longer duration and with more intensity.It's essential to understand the recovery dynamics between major disturbances so we can manage the health of the Great Barrier Reef under increased environmental pressures. Many studies modelling reef recovery assume a specific form for the growth dynamics. However, the …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Mathematical Sciences
- Research centre(s)
- Centre for Data Science
Coordinated control of multi-robot systems for environmental management
Single robotic systems can't accurately measure dynamic processes and map large areas in challenging environments. However, managing multiple robotic systems simultaneously poses many challenges around coordination and control. This is particularly true in environments where there's a lack of communication with the system. This project will explore multi-robot swarming and formation control to monitor, manage and track large-scale environmental phenomena.In this project, you will explore multi-robot swarming and coordinated formation control for dynamic process monitoring, target tracking and coordinated mapping. …
- Study level
- PhD
- Faculty
- Faculty of Engineering
- School
- School of Electrical Engineering and Robotics
- Research centre(s)
- Centre for Robotics
Novel therapeutic strategies to treat advanced colorectal cancer
Colorectal cancer is a very common disease, with over 15,000 new cases diagnosed in Australia annually. Metastatic colorectal cancer describes advanced disease that has spread beyond the primary site. This is very aggressive and incurable in the vast majority of these patients. To improve outcomes for colorectal cancer, we are using cutting edge genomic and cell biology techniques to understand disease heterogeneity and optimise drug response. We are developing novel therapeutic interventions based on unique molecular signatures and are testing …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Identifying individuals at high risk of Alzheimer’s disease
Dementia is the greatest cause of disability in Australians over the age of 65 years. In the absence of a significant medical breakthrough, more than $6.4 million Australians will be diagnosed with dementia in the next 40 years. The most common form of dementia is Alzheimer’s disease (AD), accounting for 60-80% of cases. The pathogenic process of AD begins decades prior to the clinical onset, so it is likely that treatments need to begin early in the disease process to …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Therapeutic opportunities targeting epigenetic-metabolism crosswalks in cancer
Epigenetic and metabolic pathways in cancer cells are highly interconnected. Epigenetic landscape in cancer cells is modified by oncogene-driven metabolic changes. Metabolites modulate the activities of epigenetic modifying enzymes to regulate the expression of specific genes. Conversely, epigenetic deregulation that occurs in cancer affect the expression of metabolic genes, thereby altering the metabolome. These changes all coordinately enhance cancer cell proliferation, metastasis and therapy resistance.The overall aim of the project is to understand the link between the activity of epigenetic …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
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