QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 38 matching student topics
Displaying 25–36 of 38 results
Characterising drivers of melanoma cell heterogeneity
Tumour cell heterogeneity is linked to tumour progression through the generation of divergent cellular behaviours such as proliferation, survival, invasion and therapy resistance. Crucially, conventional and targeted therapies generally only target highly proliferative cells in tumours leading to initial tumour regression, however alternative sub-populations underpin the return of treatment refractory disease and facilitate metastatic spread. Our laboratory is focused on understanding the regulatory drivers of cellular plasticity in melanoma to better understand progression and metastatic spread of this disease and …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
The role of childhood social-emotional learning competencies in adolescent health, education, and justice outcomes
This project aims to determine the relationship of childhood social-emotional competencies (particularly those developed by school-based social-emotional learning programs) with adolescent health, education, and justice outcomes. The project uses data from the NSW Child Development Study, a longitudinal study following the development of 91,597 children in NSW from birth.
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Psychology and Counselling
BIOM05 - Application of fluorescence microscopy for the visualization of methane-oxidizing microorganisms in the environment
The archaeal lineage Methanoperedenaceae are anaerobic methanotrophs with a key role in mitigating the atmospheric release of the potent greenhouse gas methane. The metabolic diversity of these microorganisms directly links methane with several key biochemical cycles and suggests a remarkable ability of these microorganisms to adapt to diverse environmental conditions.These microorganisms have never been grown in a laboratory and have only been studied in enrichment cultures with several other partner microorganisms. How these microorganisms grow and interact with these bacterial …
- Study level
- Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
-
Centre for Microbiome Research
Evaluating Navicare to improve mental health service access in regional Australia
Improved access to appropriate and timely mental health care for people in outer regional and remote areas is needed in Australia where people are disproportionately affected by severe mental health conditions. Navicare is a model of care co-designed and piloted with communities and service providers and implemented in 2021 to address this issue. In 2022 national funding from National Health and Medical Research Council was obtained to evaluate the implementation of Navicare in three new communities in Central Queensland in …
- Study level
- Honours
- School
- School of Public Health and Social Work
- Research centre(s)
- Centre for Healthcare Transformation
Australian Centre for Health Services Innovation
From a descriptive to a predictive understanding of the human microbiome
Microorganisms have a profound influence on biological, environmental, and industrial processes, but understanding the complex dynamics of microbial communities and how to manipulate them to our advantage remains a challenge. CMR Director Professor Gene Tyson has recently been awarded a prestigious ARC Laureate Fellowship that aims to overcome current technological limitations and transform microbial ecology from a descriptive to a predictive science. This will be achieved using as a model the most intensively studied ecosystem on the planet: the human …
- Study level
- PhD
- School
- School of Biomedical Sciences
- Research centre(s)
-
Centre for Microbiome Research
Metagenomic analysis of bacterial contamination screening pooled platelets
Bacterial sepsis is second only to ABO incompatibility as a cause of death from transfusion. Bacterial contamination of platelets is recognised as the most significant residual infectious risk of transfusion in developed countries. Bacterial Contamination Screening (BCS) has been required for testing of pooled and apheresis platelets manufactured by the Blood Service since April 2008. International microbiological culture studies suggest that the incidence of bacterial contamination ranges from 1:3000 to 1:1000 units of apheresis platelets and 1 in 600 to …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Using a natural β-carboline dimer compound to target metabolic vulnerabilities linked to glycolysis in prostate cancer
Prostate cancer is an androgen dependent cancer and treatments are aimed at preventing activation of the androgen receptor. Part of the development of resistance to therapies involves prostate cancers reprogramming their metabolism to overcome metabolic stress induced by these therapies and support growth and survival. This reprogramming involves increases in the rate of glycolysis and intermediate pathways branching from glycolysis. Previously in our laboratory, the natural compound, beta-carboline dimer, BD, was identified to have potent effects on cell viability, cell …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Development of bioengineered 3D tumour models for preclinical breast cancer research
3D organoid model technologies have led to the development of innovative tools for precision medicine in cancer treatment. Yet, the lack of resemblance to native tumours, and the limited ability to test drugs in a high-throughput mode, has limited translation to practice.This project will progress organoid models by using advanced tissue engineering technologies and high-throughput 3D bioprinting to recreate 'mini-tumours-in-a-dish' from a patient’s own tumour cells, and study the effects of various components of the tumour microenvironment on drug response.In …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Biomedical Technologies
Investigating genetic variants involved in Wilson disease and copper metabolism using genome editing
Wilson disease (WD) is a genetic disorder of copper metabolism. It can present with hepatic and neurological symptoms, due to copper accumulation in the liver and brain (1). WD is caused by compound heterozygosity or homozygosity for mutations in the copper transporting P-type ATPase gene ATP7B. Over 700 ATP7B genetic variants have been associated with WD. Estimates for WD population prevalence vary with 1 in 30,000 generally quoted. Early diagnosis and treatment are important for successful management of the disease. …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Genomics and Personalised Health
PHSW01 - A systematic review of internet-based interventions for supporting teachers’ mental health and wellbeing
The teaching profession is a rewarding yet intensive occupation, with teachers being at increased risk of mental health disorders. Poor mental health does not only affect the wellbeing of teachers but can also have ramifications on the health and wellbeing of students with whom teachers interact (Harding et al., 2019). Although there is a large body of research that focuses on student mental health and wellbeing, less attention has been given to understanding mental health interventions targeting teachers. Furthermore, despite …
- Study level
- Honours
- Faculty
- Faculty of Health
- School
- School of Public Health and Social Work
The use of chatbots for mental healthcare and emotional wellbeing
According to the World Health Organization, depression is the leading cause of disability, with 300 million globally suffering from it while fewer than half of those affected receive treatment. New Apps aim to help users manage their mental state, from meditation apps to more therapeutic platforms like Joyable. And a new Facebook Messenger chatbot called Woebot tries to help people with depression and other mental disorders through education and mood tracking. The focus of this research is to investigate consumers’ …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Business and Law
- School
- School of Advertising, Marketing and Public Relations
Improving platinum-based chemotherapy by targeting drug metabolism in lung cancer
Lung cancer is the deadliest cancer accounting for 18.4% of all cancer-related deaths. Platinum-based chemotherapy remains a key treatment option for most people living with this disease, either as adjuvant therapy or in combination with immunotherapy. However, resistance to therapy is a significant issue in the treatment of lung cancer. Novel therapeutic strategies combined with predictive biomarkers chemotherapy response are needed to transform the clinical management of NSCLC.Our published work has identified novel biomarkers and druggable proteins from deregulated protein …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Genomics and Personalised Health
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