QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 39 matching student topics
Displaying 25–36 of 39 results
Understanding international governance in Antarctica through cooperative game theory
Antarctica is governed by a coalition of 29 countries ('consultative parties') who must agree unanimously before a law can be passed. This project will apply theories from social network analysis and cooperative game theory to map relationships between the different parties, and to predict their behaviour on a series of important environmental issues.
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Mathematical Sciences
- Research centre(s)
-
Centre for the Environment
Prostate cancer transcriptomics (Honours and Master of Philosophy)
At the Australian Prostate Cancer Research Centre QLD, we are interested in the cellular adaptive response processes leading to therapy resistance in advanced prostate cancer.A focus area of our research is studying the transcriptome changes in prostate cancer cell lines, xenograft models and patient samples using RNA sequencing technologies.By integrating our large in-house repository of RNAseq data sets with publicly available studies, this project will further explore the cellular heterogeneity of prostate tumours and the plasticity of cancer cells in …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Studying the small proteins of the global microbiome
As part of an ARC Future Fellowship project awarded to Luis Pedro Coelho, we aim to study small proteins with the aim of better understanding them and laying the groundwork for exploiting them for biotechnological purposes. Small proteins (up to 100 amino acids, but often much shorter) have vital roles in all areas of life, but have been neglected in research due to lack of methods.Particular projects in this topic include developing methods for determining function based on genomic context, …
- Study level
- PhD, Honours
- School
- School of Biomedical Sciences
- Research centre(s)
-
Centre for Microbiome Research
Using time-controlled grazing to sequester carbon in Queensland rangelands
Time-controlled grazing (TCG), or cell grazing is a management strategy in which cattle are stocked and rotated across small paddocks or “cells” according to fodder availability. Grazing takes place in short durations at high stocking densities, in an effort to mimic the grazing patterns of wild ungulate herds.This management strategy has gained traction in recent years due to claims that it improves both pasture productivity and diversity, whilst also increasing long-term carbon pools. Limited data is available on the impact …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Biology and Environmental Science
- Research centre(s)
- Centre for Agriculture and the Bioeconomy
Comprehensive strain-level characterisation of microbial communities associated with inflammatory bowel disease
Inflammatory bowel disease (IBD) is a chronic, relapsing inflammatory disorder driven by complex interactions between environmental, microbial and immune-mediated factors 1,2. An unfavourable shift in gut microbiome composition, known as dysbiosis, is now considered a key feature of IBD 2-5, however it is unclear how specific microorganisms and their interactions with host cells contribute to disease onset and progression.Previous IBD studies have been largely limited to older sequencing methods with low phylogenetic and functional resolution. Furthermore, these studies have predominantly …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
-
Centre for Microbiome Research
Post-translational modification of proteins in cancer
The Protein Ablation Cancer Therapeutics (PACT) laboratory are interested in understanding how post-translational modifications contribute to the tumorigenic functions of proteins in cancer cells. We hypothesise that particular post-translational modifications are required for the cancer-associated function of a protein and that prevention of these would be a useful approach to treating cancer.The aim of this project is to select a candidate protein from our database of potential targets, confirm the protein is modified, identify the key modified lysine in the …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Illuminating the microbial world using genome-based fluorescence microscopy
Our understanding of microbial diversity on earth has been fundamentally changed by metagenomic characterisation of natural ecosystems. Traditional approaches for visualising microbial communities are time-consuming and provide limited information about the identity of specific microorganisms.The proposed research aims to combine single cell genomics and super resolution microscopy for novel, high-throughput, genome-based techniques to visualise microorganisms, plasmids and viruses, with strain level specificity.The application of these highly scalable approaches will provide comprehensive and unprecedented insight into the fine-scale dynamics and evolution …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
-
Centre for Microbiome Research
Biological and clinical impact of the association of germline variations in KLK3 (PSA) gene in prostate cancer
Prostate cancer is the most frequently occurring cancer (after skin cancers) in Australian males, and the second most common cause of cancer death. While the 5-year survival rate for localised disease approaches 100%, extra-prostatic invasion results in a poorer prognosis. Kallikreins are serine proteases, which are part of an enzymatic cascade pathway activated in prostate cancer (Lawrence et al 2010). The most well-known member is prostate specific antigen (PSA) or the KLK3 protein, encoded by the Kallikrein 3 (KLK3) gene, …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Moving boundary problems in mathematical biology
Invasion of biological cells or ecological populations involves moving fronts that invade into previously unoccupied regions of space. Such moving fronts are driven by a combination of motility, such as random diffusion, and proliferation, such as logistic growth. Understanding how best to model such invasive fronts is important as moving fronts of cells are associated with wound healing and cancer progression and moving fronts in ecology are associated with the spreading of weeds and invasive species.Previously both continuum and discrete …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Mathematical Sciences
The benefits of custom fit compression garments on markers of performance and recovery
Cape Bionics has its foundations in the aerospace industry in the design of compression suits worn by astronauts on the international space station. The research which underpinned the design of these space suits has now been applied to sport as a means of improving performance and recovery in elite athletes.For compression garments to be effective they must fit perfectly and apply specific pressure regimes. Cape Bionics use technology from the medical and aerospace industry to provide custom fit compression garments …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Exploring chemotherapy-induced molecular aging and its relationship to exercise
Ovarian cancer is the sixth most common cause of death from cancer in women, with a five-year survival rate of less than 45 per cent. However, there is emerging research that shows the benefits of exercise therapy during recovery following certain cancer treatments, and how exercise can improve and extend the lives of women with ovarian cancer.This project is a collaboration exploring these health and survival outcomes in ovarian and other gynaecological cancers, and in particular how new diagnostic testing …
- Study level
- Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Parameter identifiability for stochastic processes in biological systems
Stochastic models are used in biology to account for inherent randomness in many cellular processes, for example gene regulatory networks. Noise is often thought to obscure information, however, there is an increasing understanding that some randomness contains vitally important information about underlying biological processes.When applying these models to interpret and learn from data, unknown parameters in the model need to be estimated. However, not all data will contribute to a given estimation task regardless of the data quantity and quality. …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Mathematical Sciences
- Research centre(s)
- Centre for Data Science
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