QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 123 matching student topics
Displaying 97–108 of 123 results
Developing in vitro 3D models to understand liver disease
Several studies have demonstrated the appropriateness of 3D organoid cultures over the conventional 2D cultures, the advantages of 3D models include replicating the complex attributes of the liver beyond liver-specific metabolism, such as increased cell density, organization, and cell–cell signalling, O2 zonation.In this project we will establish a novel in vitro 3D model to study hepatocyte biology in the context of liver disease. A more comprehensive approach to investigating the intercellular mechanisms of NAFLD will include co-culture of organoids with …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Multi-microbial 3D printing for screening microbiome functions
The ability to 3D print bacteria has relevance to a wide range of applications, ranging from developing novel anti-microbial modalities to probiotics for promoting human health. Traditional culture techniques used in microbiology such as agar plates and suspension cultures have limited spatio-temporal control over the bacteria microenvironment as well as their interaction partners, in particular, mammalian host cells. This project aims to bridge this technological gap by combining 3D printing and microfluidics technologies to spatially control the localisation of multiple …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Adaptive evolution of anaerobic methanotrophic (ANME) archaea mediating methane oxidation in freshwater environments (PhD)
The as-yet-uncultured archaeal lineage Methanoperedenaceae are anaerobic methanotrophs with a key role in mitigating the atmospheric release of methane in freshwater environments. The metabolic diversity of these microorganisms directly links methane with several key biochemical cycles and suggests a remarkable ability of these microorganisms to adapt to diverse environmental conditions.The overall aim of this PhD project will be to uncover the metabolic diversity of the Methanoperedenaceae and to understand the evolutionary mechanisms responsible for these adaptations.Methods and ResourcesThe project will …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
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Centre for Microbiome Research
Illuminating the microbial world using genome-based fluorescence microscopy
Our understanding of microbial diversity on earth has been fundamentally changed by metagenomic characterisation of natural ecosystems. Traditional approaches for visualising microbial communities are time-consuming and provide limited information about the identity of specific microorganisms.The proposed research aims to combine single cell genomics and super resolution microscopy for novel, high-throughput, genome-based techniques to visualise microorganisms, plasmids and viruses, with strain level specificity.The application of these highly scalable approaches will provide comprehensive and unprecedented insight into the fine-scale dynamics and evolution …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
-
Centre for Microbiome Research
Food literacy projects (see description for options)
Food Literacy is a collection of knowledge, skills and behaviours required to plan, manage, select, prepare and eat foods to meet needs and determine food intake. It is the scaffolding that empowers individuals, households, communities or nations to protect diet quality through change and strengthen dietary resilience over time. Areas for further research include, but are not limited to:identifying models to integrated food literacy into dietetic practice e.g. through the Nutrition Care Processdevelop population level indicators for food literacy that …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Exercise and Nutrition Sciences
Food literacy and children
The term food literacy has been empirically for adults, but not for children. It is likely that the definition would differ for children (including adolescents). Possible research projects in this area include but are not limited to:investigating children's role in feeding themselves, in particular the variables that impact on this; and diet quality and food choice pathways that children use, the impact of economic disadvantage, culture, gender, age, geographydefining and conceptualising food literacy for childrenconceptualising food literacy by those developing …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Exercise and Nutrition Sciences
Community and Public Health Nutrition Workforce
The training of a specialised community and public health nutrition (CPHN) workforce assumes they are optimally placed to address food and nutrition issues at a population and community level. However, concomitant with the rise of diet as the leading risk factor contributing to the burden of disease in Australia, has been a dramatic disinvestment in this workforcePermanent, full time nutritionist positions embedded in communities or population settings are few. If an organisation invests in a nutrition intervention it is increasingly …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Exercise and Nutrition Sciences
Aboriginal and Torres Strait Islander food and nutrition projects
Aboriginal and Torres Strait Islander peoples suffer disproportionally from diet-related conditions in Australia. Much current research is deficit based, however this body of work aims to be strengths based. Research projects could include, but are not limited to:a descriptive/explorative of food literacy among Aboriginal and Torres Strait Islander people using an assets based framework exploring positive deviants.a food sovereignty project to describe Aboriginal and Torres Strait Islander foodways. This could be applied to a particular nation group. It could be …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Exercise and Nutrition Sciences
Using a natural β-carboline dimer compound to target metabolic vulnerabilities linked to glycolysis in prostate cancer
Prostate cancer is an androgen dependent cancer and treatments are aimed at preventing activation of the androgen receptor. Part of the development of resistance to therapies involves prostate cancers reprogramming their metabolism to overcome metabolic stress induced by these therapies and support growth and survival. This reprogramming involves increases in the rate of glycolysis and intermediate pathways branching from glycolysis. Previously in our laboratory, the natural compound, beta-carboline dimer, BD, was identified to have potent effects on cell viability, cell …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
A preclinical evaluation pipeline for new antivirulence drugs targeting multidrug resistant bacterial pathogens
A post-antibiotic era—in which common infections and minor injuries can kill—far from being an apocalyptic fantasy, is instead a very real possibility for the 21st century.’ - WHO, 2014 (1). Antimicrobial resistance (AMR) is a global public health priority. If no action is taken, AMR is predicted to kill more people than cancer and diabetes combined by 2050, with 10 million deaths estimated each year and a global cost of up to 100 trillion USD. New therapies to tackle multidrug …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Characterisation of emerging multidrug resistant E. coli pathogens
The last fifteen years have witnessed an unprecedented rise in the rates of antimicrobial resistance among Gram-negative bacteria, described by the World Health organisation as a global health crisis (1). Escherichia coli sequence type 131 (E. coli ST131) is a ‘high-risk’ group of Gram-negative pathogens that have emerged rapidly and spread worldwide in the period of the last 10 years (2). E. coli ST131 strains are typically resistant to multiple classes of antibiotics and cause bloodstream and urinary tract infections …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Providing legal evidence for non-accidental scald burn injury
Although most burn injuries are completely accidental in nature, they can also occur due to neglect or abuse. Burn clinicians are often required to ascertain if the patient history and the wound are consistent with accidental or non-accidental injury. If the case goes to court, the clinician will prepare a medico-legal report as evidence. We have previously conducted studies examining the depth of burn injury after different durations and temperatures of hot water. This data can be used to predict …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
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