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Managing motion in radiotherapy treatments

The outcomes of radiotherapy treatments are influenced by patient motion such as breathing during the delivery of the treatment.A number of research projects are available to investigate and develop new techniques for measuring and managing motion during the radiotherapy treatment. These include imaging and surface measurement during treatment.

Study level
Vacation research experience scheme
Faculty
Faculty of Science
School
School of Chemistry and Physics
Research centre(s)
Centre for Biomedical Technologies

Hearing colour and seeing sound – switchable optoacoustic imaging agents

Optoacoustic imaging is a relatively new medical imaging technique. It utilises laser light to excite an imaging agent, which in turn converts this light energy into heat. This heat is dissipated as a sound wave, which can be detected with an ultrasound receiver. This technique aims to overcome the minimal penetration depth of fluorescence imaging, and the lack of molecular specificity of ultrasound.In this project we are aiming to develop and synthesize intelligent imaging agents for optoacoustics, which are able …

Study level
Master of Philosophy, Honours, Vacation research experience scheme
Faculty
Faculty of Science
School
School of Chemistry and Physics
Research centre(s)
Centre for Materials Science

Advanced artificial intelligence based ultrasound imaging applications

Our research in the space of advanced quantitative medical imaging is investigating how to use ultrasound as a real time volumetric mapping tool of human tissues, to guide in a reliable and accurate way complex medical procedures1. We have developed several novel methods which make use of the most cutting-edge artificial intelligence technology2. For example, to show where the treatment target and the organs at risk are at all times during treatments in radiation therapy3, 4; or to inform robots …

Study level
PhD, Master of Philosophy
Faculty
Faculty of Health
School
School of Clinical Sciences
Research centre(s)
Centre for Biomedical Technologies

Identifying individuals at high risk of Alzheimer’s disease

Dementia is the greatest cause of disability in Australians over the age of 65 years. In the absence of a significant medical breakthrough, more than $6.4 million Australians will be diagnosed with dementia in the next 40 years. The most common form of dementia is Alzheimer’s disease (AD), accounting for 60-80% of cases. The pathogenic process of AD begins decades prior to the clinical onset, so it is likely that treatments need to begin early in the disease process to …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

Mathematical and computational models for diffusion magnetic resonance imaging (dMRI)

In 1985, the first image of water diffusion in the living human brain came to life. Since then significant developments have been made and diffusion magnetic resonance imaging (dMRI) has become a pillar of modern neuroimaging.Over the last decade, combining computational modelling and diffusion MRI has enabled researchers to link millimetre scale diffusion MRI measures with microscale tissue properties, to infer microstructure information, such as diffusion anisotropy in white matter, axon diameters, axon density, intra/extra-cellular volume fractions, and fibre orientation …

Study level
PhD, Master of Philosophy, Honours, Vacation research experience scheme
Faculty
Faculty of Science
School
School of Mathematical Sciences
Research centre(s)
Centre for Data Science
Centre for Biomedical Technologies

Estimating the evolutionary history of plasmids and viruses

In the case of cellular life - bacteria, archaea and eukaryotes - determining the 'tree of life' is a comparatively well-studied problem.This vertical evolutionary history can be estimated using concatenated gene phylogenies, where single copy marker genes are concatenated into a single multiple sequence alignment which is then used in a phylogenetic tree reconstruction algorithm.Viral genomes and plasmid sequences, meanwhile, are more challenging to fit into a phylogenetic framework.

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)

Centre for Microbiome Research

Optical coherence tomography imaging of arterial tissue

The sudden rupture of vulnerable atherosclerotic plaques and subsequent thrombosis formations are responsible for most acute vascular syndromes, such as myocardial infarction and stroke. Many victims who are apparently healthy die suddenly with no prior symptoms.Such deaths could be prevented through surgery or alternative medical therapy, if vulnerable plaques were identified earlier in their natural progression.While intravascular methods have been developed to visualize various features of vulnerable plaques, there is no single technique that can accurately predict plaque rupture in …

Study level
PhD, Master of Philosophy, Honours, Vacation research experience scheme
Faculty
Faculty of Engineering
School
School of Mechanical, Medical and Process Engineering
Research centre(s)
Centre for Biomedical Technologies

AI-Based Data Analysis on Multiple Imaging Modalities

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality globally. According to the World Health Organization (WHO), it is estimated CVD takes 17.9 million lives every year. In Australian, the statistical data from the Australia Heart Foundation shows CVD is a major cause of death in Australia. It occupies 26% of all deaths, responsible for an average 118 deaths every day. Four of the main types of CVD are coronary heart disease, strokes and transient ischaemic attack, peripheral …

Study level
PhD, Master of Philosophy, Honours, Vacation research experience scheme
Faculty
Faculty of Science
School
School of Computer Science
Research centre(s)
Centre for Data Science

Foundations: speculative imaginings of law and technology

This project is located within the 'Jurisprudence of the Future' project which is an international collective exploring the intersections and connections between science fiction and law. At this stage of the project the overarching focus will be on a volume with Routledge edited by Mitch Travis and Kieran Tranter.You will work directly with myself and coauthors on an original chapter for that volume that connects and works through an aspect of the speculative imaginings of law and technology. The precise …

Study level
Vacation research experience scheme
Faculty
Faculty of Business and Law
School
School of Law

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