QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.

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Found 90 matching student topics

Displaying 13–24 of 90 results

Voluntary assisted dying, medical practitioners and conscientious objection

Should legislation permitting Voluntary Assisted Dying (VAD) provide medical practitioners with a right to conscientiously object to VAD and, if so, what should the scope of that right be?Should it include a right not to give a person asking about VAD any information about it? In Victoria the legislation provides an unrestricted right to conscientiously object whereas in Western Australia the right to object is qualified by a requirement to give the patient information about VAD. Which position is most …

Study level
PhD
Faculty
Faculty of Business and Law
School
School of Law
Research centre(s)

Australian Centre for Health Law Research

Medical selfies and patient generated health data

Smartphones and wearable technologies provide exciting opportunities for patients and health professionals to transform healthcare.Patients can benefit from photos (“medical selfies”) taken on their smartphone to record a condition that they want to discuss with a health professional. Wearable devices allow patients to semi-automatically collect data about their physical activity, sleep, mood, diet, etc.This data can help patients to better understand a health concern, its underlying causes and the impact of treatments.Clinicians, on the other hand, can benefit from medical …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Science
School
School of Computer Science

Develop microfluidic technologies for cardiovascular and cerebrovascular diseases

The sudden rupture of vulnerable atherosclerotic plaques and subsequent thrombosis formations are responsible for most acute vascular syndromes, such as myocardial infarction and stroke. Many victims who are apparently healthy die suddenly with no prior symptoms. Such deaths could be prevented through surgery or alternative medical therapy, if vulnerable plaques were identified earlier in their natural progression.To address this pressing need, we're developing simple-to-use, high-throughput and highly-informative microfluidic biochips to understand the sequences of molecular events underlying biomechanical thrombosis (mechanobiology). …

Study level
PhD, Master of Philosophy
Faculty
Faculty of Engineering
School
School of Mechanical, Medical and Process Engineering
Research centre(s)
Centre for Biomedical Technologies

A new physics informed machine learning framework for structural optimisation design of the biomedical devices

The machine learning based computer modelling and simulation for engineering and science is a new era. The optimisation analysis is widely used in the design of structures.

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Engineering
School
School of Mechanical, Medical and Process Engineering
Research centre(s)
Centre for Biomedical Technologies
Centre for Biomedical Technologies

Bio-inspired design to create strong and toughness composites

A fundamental challenge to materials design for mechanical capability is to attain both strength and toughness at the same time in one body. Conventional metallic materials generally have relatively large plasticity due to having massive population of microstructural defects and effective plastic deformation mechanism, which have long been exploited for fabricating flaw tolerant (toughness) materials for structural applications. By the same token theseStructural defects render the materials relatively low strength, thus low load-bearing capability. In contrast, ceramics and intermetallic compounds …

Study level
PhD, Master of Philosophy
Faculty
Faculty of Engineering
School
School of Mechanical, Medical and Process Engineering
Research centre(s)
Centre for Materials Science

Image-based computational model to predict intracranial aneurysm rupture

Intracranial aneurysms are bulging, weak areas of an artery that supply blood to the brain which are relatively common. While most aneurysms do not show symptoms, 1% spontaneously rupture which can be fatal or it can leave the survivor with permanent disabilities. This catastrophic outcome has motivated surgeons to operate on approximately 30% of aneurysms despite their rate of complications arising and cost of operation.The impact of aneurysm morphology on blood flow shear stress and rupture could educate surgical decision-making …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Engineering
School
School of Mechanical, Medical and Process Engineering
Research centre(s)
Centre for Biomedical Technologies

Providing legal evidence for non-accidental scald burn injury

Although most burn injuries are completely accidental in nature, they can also occur due to neglect or abuse. Burn clinicians are often required to ascertain if the patient history and the wound are consistent with accidental or non-accidental injury. If the case goes to court, the clinician will prepare a medico-legal report as evidence. We have previously conducted studies examining the depth of burn injury after different durations and temperatures of hot water. This data can be used to predict …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

Development of bioengineered 3D tumour models for preclinical breast cancer research

3D organoid model technologies have led to the development of innovative tools for precision medicine in cancer treatment. Yet, the lack of resemblance to native tumours, and the limited ability to test drugs in a high-throughput mode, has limited translation to practice.This project will progress organoid models by using advanced tissue engineering technologies and high-throughput 3D bioprinting to recreate 'mini-tumours-in-a-dish' from a patient’s own tumour cells, and study the effects of various components of the tumour microenvironment on drug response.In …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)
Centre for Biomedical Technologies

The role of genetics in the development and mechanism of human traits

The Statistical and Genomic Epidemiology Laboratory (SGEL) studies the role of genetics in the development and mechanism of human traits, with particular emphasis on migraine, and the specific goal of identifying genetic risk factors and detecting common genetic links with other disorders, in particular depression, endometriosis, and epilepsy.

Study level
PhD, Master of Philosophy
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)
Centre for Genomics and Personalised Health

Giant viruses in the human gut microbiome

The human body is home to a vast ecosystem of microorganisms including bacteria, archaea, fungi, viruses, and bacteriophages that make up the human microbiota. These microbes and their collective genetic material, known as the microbiome, influence a wide range of physiological functions including nutrient production and absorption, the development and regulation of our immune system, protection against potential pathogens, and even our mood and mental health. While distinct microbial communities exist throughout the body, the gut microbiome has gained particular …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)

Centre for Microbiome Research

Using a natural β-carboline dimer compound to target metabolic vulnerabilities linked to glycolysis in prostate cancer

Prostate cancer is an androgen dependent cancer and treatments are aimed at preventing activation of the androgen receptor. Part of the development of resistance to therapies involves prostate cancers reprogramming their metabolism to overcome metabolic stress induced by these therapies and support growth and survival. This reprogramming involves increases in the rate of glycolysis and intermediate pathways branching from glycolysis. Previously in our laboratory, the natural compound, beta-carboline dimer, BD, was identified to have potent effects on cell viability, cell …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

A preclinical evaluation pipeline for new antivirulence drugs targeting multidrug resistant bacterial pathogens

A post-antibiotic era—in which common infections and minor injuries can kill—far from being an apocalyptic fantasy, is instead a very real possibility for the 21st century.’ - WHO, 2014 (1). Antimicrobial resistance (AMR) is a global public health priority. If no action is taken, AMR is predicted to kill more people than cancer and diabetes combined by 2050, with 10 million deaths estimated each year and a global cost of up to 100 trillion USD. New therapies to tackle multidrug …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

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