QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 118 matching student topics
Displaying 1–12 of 118 results
Investigating the role of Neuropilin-1 in Triple-Negative Breast Cancer metastasis and chemoresistance
Triple-negative breast cancers (TNBC) are negative for Estrogen Receptor, Progesterone Receptor and HER2 expression, are clinically aggressive and are unresponsive to the available hormonal or targeted drugs used for other breast cancer subtypes, so that TNBC patients rely mainly on chemotherapy. TNBC accounts for 15-20% of all invasive breast cancer and patients have increased risk of recurrence, mortality and early metastatic progression. Thus, there is an urgent clinical need to develop improved treatment strategies for TNBC. Neuropilin-1 (NRP1) is a …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Dietary counselling for nutrition-impacting symptoms during cancer treatment
Nutrition-impacting symptoms contribute to decreased quality of life and food intake, and subsequent malnutrition and decreased willingness to commence or complete cancer treatment, which all compromise survival. Evidence exists to support the role of dietary counselling for malnutrition during cancer treatment; however, less is known about the role of dietary counselling for nutrition-impacting symptoms that lead to the development of malnutrition.This systematic review project will synthesise available evidence on the effect of dietary counselling interventions on nutrition-impacting symptoms (e.g., fatigue, …
- Study level
- Honours
- Faculty
- Faculty of Health
- School
- School of Nursing
- Research centre(s)
- Centre for Healthcare Transformation
Cancer and Palliative Care Outcomes Centre
The benefits of custom fit compression garments on markers of performance and recovery
Cape Bionics has its foundations in the aerospace industry in the design of compression suits worn by astronauts on the international space station. The research which underpinned the design of these space suits has now been applied to sport as a means of improving performance and recovery in elite athletes.For compression garments to be effective they must fit perfectly and apply specific pressure regimes. Cape Bionics use technology from the medical and aerospace industry to provide custom fit compression garments …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Assessing visual acuity errors in pre-school children (CVER01)
Measuring visual acuity is in preschool children is challenging. In particular, young children will be prone to making mistakes in identifying symbols on eye charts, even when they can see what those symbols are, so called “false negative responses”.This project uses an established vision assessment protocol, EVA testing, and assesses the extent of false negative responses in this task. The protocol assesses the effects of an intervention, pointing to the target on a card, which may decrease false negative responses. …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Clinical Sciences
- Research centre(s)
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Centre for Vision and Eye Research
Reversing Epithelial Mesenchymal Plasticity with Eribulin to Enhance Therapy Response
Epithelial mesenchymal plasticity (EMP) is a highly regulated and powerful cellular process that is fundamental in embryonic development (1), which is hijacked by cancer cells for metastatic progression and therapy resistance in epithelial cancers (2). Eribulin is a microtubule-inhibiting cancer drug discovered in sea sponges and approved for 3rd line therapy in metastatic breast cancer, which was shown to reverse epithelial mesenchymal transition (EMT) (3).We hypothesise that eribulin’s reversal of EMT will sensitise breast cancer cells to other therapies and …
- Study level
- Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Genetics of cardiovascular disease
This research project involves investigating the genetic basis of cardiovascular disease (CVD). The project will focus on the genetically unique population of Norfolk Island. The Norfolk Island Health Study has been running for 20 yrs. Over this time the cardiovascular health of the Islanders has been tracked via the collection of relevant clinical data. In addition whole genome sequence data from the study group has been collected, which will facilitate the discovery of genetic variants that influence CVD phenotypes - …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Genomics and Personalised Health
Human biomarkers of stress, trauma, and memories of fear
Understanding how disorders such as posttraumatic stress disorder develop following trauma is a contemporary challenge for researchers in psychology. The best explanations involve a combination of psychological and biological factors that interact during and following trauma to create a range of troubling symptoms. This project will use cutting edge technology at QUT to provide insights into how a mix of biology and behaviour can result in exacerbated stress responses and threat memories in experimental and real-world settings.
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Psychology and Counselling
Preventing arterial catheter-related harm in intensive care
Each year more than 200,000 patients (adults and children) are admitted to intensive care units (ICU) in Australia and New Zealand for treatment of serious and life-threatening injury or illness, or recovery from major surgery. The vast majority (~90%) of ICU patients will require an arterial catheter during their admission to optimise vital treatment and monitoring. Arterial catheters are small hollow plastic tubes inserted into peripheral arteries to facilitate continuous haemodynamic monitoring (e.g. blood-pressure) and frequent blood sampling. Hence, effective …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Nursing
- Research centre(s)
- Centre for Healthcare Transformation
Healthcare providers’ perspectives on wound care in aged care facilities
The ageing of the population in Australia, in line with other developed countries, is well documented, with the trend giving rise to an increase in incidence and prevalence of health conditions and complex health states for which age is a significant risk factor. As the skin ages, reduced moisture and loss of elasticity places the older person at increased risk of a variety of wounds such as skin tears and pressure injuries. In addition, the presence of multiple comorbid conditions …
- Study level
- Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Nursing
- Research centre(s)
- Centre for Healthcare Transformation
Identifying novel pheno-endotypes in children with chronic cough
Chronic wet cough is among the commonest symptoms of chronic lung disease. In Australia, the most common cause of childhood chronic wet cough is protracted bacterial bronchitis (PBB), a clinical entity we first described. It has now been shown to be a precursor to bronchiectasis, which causes substantial morbidity and mortality, especially from acute respiratory exacerbations. Lung inflammation in children with persistent chronic wet cough is an important driver of ongoing and progressive tissue damage, leading to bronchiectasis, highlighting the …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Public Health and Social Work
- Research centre(s)
- Centre for Healthcare Transformation
Australian Centre for Health Services Innovation
The role of childhood social-emotional learning competencies in adolescent health, education, and justice outcomes
This project aims to determine the relationship of childhood social-emotional competencies (particularly those developed by school-based social-emotional learning programs) with adolescent health, education, and justice outcomes. The project uses data from the NSW Child Development Study, a longitudinal study following the development of 91,597 children in NSW from birth.
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Psychology and Counselling
The role of genetics in the development and mechanism of human traits
The Statistical and Genomic Epidemiology Laboratory (SGEL) studies the role of genetics in the development and mechanism of human traits, with particular emphasis on migraine, and the specific goal of identifying genetic risk factors and detecting common genetic links with other disorders, in particular depression, endometriosis, and epilepsy.
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Genomics and Personalised Health
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