Dr Bingyin Peng

Biography

Bingyin Peng is a Research Fellow (yeast engineering & industrial  genetics) in the School of Biology and Environmental Science and the Centre of Agriculture and Bioeconomy, QUT. His career has been focusing on yeast engineering to develop the superior strains for utilisation of C5 sugars and production of value-added chemicals from cane sugars -- the tasks in biomass refinery theme. His current scientific interest areas include fundamental microbial genetics, metabolic engineering, molecular genetic evolution, and rational genetic design. He is interested in applying his scientific findings to create industrial biotechnology applications for sustainable biomanufacturing and economic growth in remote regions.

He obtained a Bachelor degree in Biochemistry and Molecular Biology from Liaoning University (China) in 2008 and a Master's degree in Microbiology from Shandong University (China) in 2011. He completed his PhD in Industrial Biotechnology and Synthetic Biology at the University of Queensland in 2018.

His current works focus on:

Understanding and overcoming metabolic imbalance, discovering genetic basis for biological replicates, education kit for visualization of genome evolution, precision genetic induction systems, characterising nutrient/stress sensing mechanisms/pathways, developing new genetic engineering tools.

Previously he  has completed  the following projects:

Deploying regulatory network engineering for advanced yeast biorefinary (July 2018 – June 2021)

• Breaking flask-cultivation titre record (~1 g L-1) for limonene (monoterpene) production in yeast
• Breaking flask-cultivation titre record (~3.4 g L-1) for nerolidol (sesquiterpene) production in yeast
• Innovated haploinsufficiency-drive in situ gene amplification on genome
• A series of metabolic regulatory tools: plant auxin-mediated protein degradation tool, tetracycline-repression circuit, temperature-mediated genetic circuits.

Modulating gene expression in yeast to optimize metabolic networks for sesquiterpene and monoterpene production (July 2013 – July 2017)

• Breaking flask-cultivation titre record (~0.1 g L-1) for limonene (monoterpene) production in yeast
• A series of metabolic regulatory tools: protein degradation tools for flux redirection, heterologous GAL promoter tool for multigenic pathway reconstruction.

Green chemical manufacturing from lignocellulosic substrates (July 2011 – June 2013)

• Developed whole-sugar-utilizing yeast platforms and designed the metabolic pathways for muconic acid and 2,3-butadiol production

Improvement of Ethanolic Fermentation of Xylose in Saccharomyces cerevisiae by Pathway Engineering and Evolutionary Engineering (October 2008 – June 2011)

• Breaking the record in China to enable efficient anaerobic xylose fermentation in S. cerevisiae.