QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 285 matching student topics
Displaying 109–120 of 285 results
Making predictions using simulation-based stochastic mathematical models
Stochastic simulation-based models are very attractive to study population-biology, disease transmission, development and disease. These models naturally incorporate randomness in a way that is consistent with experimental measurements that describe natural phenomena.Standard statistical techniques are not directly compatible with data produced by simulation-based stochastic models since the model likelihood function is unavailable. Progress can be made, however, by introducing an auxiliary likelihood function can be formulated, and this auxiliary likelihood function can be used for identifiability analysis, parameter estimation and …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Science
- School
- School of Mathematical Sciences
- Research centre(s)
- Centre for Data Science
Scalable software solutions for improving the CRISPR gene editing system
The CRISPR-Cas9 technology allows the modification of virtually any gene in any organism of interest. It has generated a lot of interest, both in the research community and the general population.One of the crucial components of CRISPR experiments is the design of the 'guide RNAs' that will control where modifications occur. We have developed a software pipeline, named Crackling, to identify safe and effective guide RNAs across entire genomes.We are seeking to expand and improve various aspects of our current …
- Study level
- Honours
- Faculty
- Faculty of Science
- School
- School of Computer Science
- Research centre(s)
- Centre for Data Science
Visualisation of CRISPR targets
CRISPR-Cas9 technology allows us to modify virtually any gene in any organism of interest. It has generated a lot of interest, both in the research community and the general population.One of the crucial components of CRISPR experiments is the design of the 'guide RNAs' that will control where modifications occur.We have developed a software pipeline, named Crackling, to identify safe and effective guide RNAs across entire genomes. We're now seeking to develop a visualisation to communicate the results produced by …
- Study level
- Honours
- Faculty
- Faculty of Science
- School
- School of Computer Science
- Research centre(s)
- Centre for Data Science
Novel therapeutic strategies to treat advanced colorectal cancer
Colorectal cancer is a very common disease, with over 15,000 new cases diagnosed in Australia annually. Metastatic colorectal cancer describes advanced disease that has spread beyond the primary site. This is very aggressive and incurable in the vast majority of these patients. To improve outcomes for colorectal cancer, we are using cutting edge genomic and cell biology techniques to understand disease heterogeneity and optimise drug response. We are developing novel therapeutic interventions based on unique molecular signatures and are testing …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Investigating genetic variants involved in Wilson disease and copper metabolism using genome editing
Wilson disease (WD) is a genetic disorder of copper metabolism. It can present with hepatic and neurological symptoms, due to copper accumulation in the liver and brain (1). WD is caused by compound heterozygosity or homozygosity for mutations in the copper transporting P-type ATPase gene ATP7B. Over 700 ATP7B genetic variants have been associated with WD. Estimates for WD population prevalence vary with 1 in 30,000 generally quoted. Early diagnosis and treatment are important for successful management of the disease. …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Genomics and Personalised Health
The dark side of robotic process automation
Pandemics such as COVID 19 have forced organisations to pursue hyper-automation to maintain operational sustainability. Many organisations are keen to adopt Robotic Process Automation (RPA) to dramatically improve operational efficiency. However, evidence to date highlighted various associated challenges associated with adoption of RPA in organisations.Furthermore, recent surveys by consultant organisations found a high RPA project fail rate and their inability to meet the expected return on investment.
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Information Systems
- Research centre(s)
- Centre for Future Enterprise
Development of a Microfluidic Gut-Brain Axis Chip
The gut microbiome refers to the collection of micro-organisms that are living symbiotically in the human or animal gastrointestinal tract (defined as the “microbiota”), their genetic material as well as the surrounding environmental habitat. It is now appreciated that the microbiome plays an important role in human health and diseases. Many neurodegenerative diseases, such as Parkinson's Disease have been linked to dysregulation of the gut microbiota. However, it is difficult to study gut-brain axis using animal models due to inter-species …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
- Centre for Biomedical Technologies
Centre for Microbiome Research
International entrepreneurship
How do entrepreneurs grow their new ventures across borders? What role do key individuals or teams of entrepreneurs and their collective experiences, skills, relational capabilities and identities play in new venture success? How do entrepreneurs identify and leverage external enablers to enhance new venture legitimacy and propel rapid internationalisation? Are these external enablers ‘out there’ waiting to be harnessed, or can entrepreneurs shape their external environment through, for example, ‘institutional entrepreneurship’? International Entrepreneurship is an area with many unanswered and …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Business and Law
- School
- School of Advertising, Marketing and Public Relations
- Research centre(s)
-
Australian Centre for Entrepreneurship Research
Mean exit time calculations in complicated geometries
Calculating the duration of time required for a diffusive process to end is a classical problem in mathematics, engineering, biology and economics. The concept of mean exit time is widely used to study transport phenomena in biology, such as calculating the duration of time required for a protein created in a cell nucleus to reach the cell membrane. While many exact calculations of mean exit time are known for simple geometries and homogeneous media, exact solutions are rare for complicated …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Mathematical Sciences
Exact and approximate solutions of diffusion on evolving domains
Classical applications of mathematical analysis involve solving partial differential equation models on fixed domains, e.g. 0 < x < L. Applications in biology, however, involve studying diffusive transport on rapidly evolving domains, e.g. 0 < x < L(t), where L(t) represents the length of the evolving tissue. While many problems have been addressed for the case where L(t) increases, less attention has been paid to cases where we consider diffusion on an oscillating domain.In this project we will construct exact …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Mathematical Sciences
Foreign direct investment for inclusive growth
Multinational enterprises (MNEs) attract a lot of bad press worldwide, sometimes with good cause: think of MNEs not paying their taxes, or possible threats to national security. Easily overlooked, however, are the extensive benefits that foreign direct investment (FDI) can bring to a host economy. This includes ‘spillovers’ from foreign firms and domestic multinational eneterprises that boost the productivity and innovation of local firms. This research project explores the mechanisms by which FDI impacts the productivity and innovation in domestic …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Business and Law
- School
- School of Advertising, Marketing and Public Relations
- Research centre(s)
-
Australian Centre for Entrepreneurship Research
International business strategy and entrepreneurship
I’m interested in supervising research students who have a passion for research, ambition to publish in leading journals, and the commitment needed to excel. My interests within International Business are broad, including the strategies of large multinational enterprises as well as small firms as they internationalise; international entrepreneurship in established firms, by new firms or by entrepreneurial teams; power and identity in MNE-subsidiary relations; and how foreign direct investment can help domestic firms’ productivity and innovation. My preference is for …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Business and Law
- School
- School of Advertising, Marketing and Public Relations
- Research centre(s)
-
Australian Centre for Entrepreneurship Research
Contact us
If you have questions about the best options for you, the application process, your research topic, finding a supervisor or anything else, get in touch with us today.