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Found 14 matching student topics

Displaying 13–14 of 14 results

Making predictions using simulation-based stochastic mathematical models

Stochastic simulation-based models are very attractive to study population-biology, disease transmission, development and disease. These models naturally incorporate randomness in a way that is consistent with experimental measurements that describe natural phenomena.Standard statistical techniques are not directly compatible with data produced by simulation-based stochastic models since the model likelihood function is unavailable. Progress can be made, however, by introducing an auxiliary likelihood function can be formulated, and this auxiliary likelihood function can be used for identifiability analysis, parameter estimation and …

Study level
PhD, Master of Philosophy
Faculty
Faculty of Science
School
School of Mathematical Sciences
Research centre(s)
Centre for Data Science

Traces of zinc and ciprofloxacin loaded polymer nanoparticulate inhaled formulations against lung infections associated with COPD and CF (CLIN08)

Lower respiratory tract infections (LRTIs) are one of the fatal diseases of the lungs that have severe impacts on public health, especially for Indigenous people. The currently available antibiotics administered orally for the treatment of LRTIs need high doses with frequent administration and cause dose-related adverse effects. To overcome this problem, we will investigate the development of ciprofloxacin (CIP) loaded poly(2-ethyl-2-oxazoline) (PEtOx) nanoparticles (NPs) with traces of zinc for potential pulmonary delivery from dry powder inhaler (DPI) formulations. As zinc …

Study level
PhD
Faculty
Faculty of Health
School
School of Clinical Sciences
Research centre(s)

Centre for Immunology and Infection Control

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