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Found 3 matching student topics

Displaying 1–3 of 3 results

Mathematical modelling of cell-to-cell communication via extracellular vesicles (EVs)

Extracellular vesicles (EVs) are membrane bound packages of information constantly being released by all living cells, including bacteria. There are many types and sizes of EVs. Each EV type contains its own distinctive cargo consisting of characteristic DNA, RNA, and proteins. We are just beginning to understand the many roles of EVs to maintain the health of the cell producing the EVs, and to communicate with other cell types that take up the EVs produced by neighbouring cells. Since EVs …

Study level
Honours
Faculty
Faculty of Science
School
School of Mathematical Sciences

Traces of zinc and ciprofloxacin loaded polymer nanoparticulate inhaled formulations against lung infections associated with COPD and CF (CLIN08)

Lower respiratory tract infections (LRTIs) are one of the fatal diseases of the lungs that have severe impacts on public health, especially for Indigenous people. The currently available antibiotics administered orally for the treatment of LRTIs need high doses with frequent administration and cause dose-related adverse effects. To overcome this problem, we will investigate the development of ciprofloxacin (CIP) loaded poly(2-ethyl-2-oxazoline) (PEtOx) nanoparticles (NPs) with traces of zinc for potential pulmonary delivery from dry powder inhaler (DPI) formulations. As zinc …

Study level
PhD
Faculty
Faculty of Health
School
School of Clinical Sciences
Research centre(s)

Centre for Immunology and Infection Control

Polymer theranostics for nanomedicine

The personalised treatment of disease though nanomedicine will allow for more effective and safer treatments for patients. Polymer theranostics provide for the simultaneous detection of disease, treatment, and monitoring of therapeutic response. Our research group synthesises new polymeric materials and investigates how they can be used in applications such as:potent antivirals to fight future pandemicsthe effect of radiation on materials for improved radiotherapy for cancerresponsive imaging agents that can report on metabolic processes of diseasecharacterizing the interaction of polymeric materials …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Science
School
School of Chemistry and Physics
Research centre(s)
Centre for Materials Science

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