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Found 3 matching student topics

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Wound care in people with dementia: the silent unknown

The incidence of both dementia and chronic wounds increases with age, thus, given the ageing population, the overlap is strong.Clinicians report managing wounds in adults with dementia is a frequent and challenging problem, yet people with dementia are generally excluded from research into evidence-based wound care despite impaired cognition, high incidence of falls, immobility and incontinence, all of which are recognised risk factors for skin tears and chronic wounds.This project aims to investigate the evidence in regard to dementia and …

Study level
PhD, Master of Philosophy
Faculty
Faculty of Health
School
School of Nursing

Identifying individuals at high risk of Alzheimer’s disease

Dementia is the greatest cause of disability in Australians over the age of 65 years. In the absence of a significant medical breakthrough, more than $6.4 million Australians will be diagnosed with dementia in the next 40 years. The most common form of dementia is Alzheimer’s disease (AD), accounting for 60-80% of cases. The pathogenic process of AD begins decades prior to the clinical onset, so it is likely that treatments need to begin early in the disease process to …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

BIOM01 - Novel therapeutic strategies for targeting dementia

Dementia exhibits the presence of Lewy bodies in the cerebral cortex, which are composed of α-synuclein (αSYN) or Amyloid-β (Aβ) plaques, as well as hyperphosphorylated tau (P-tau) tangles in various forms of dementia. The exact pathological mechanisms underlying this disease are not well understood; however, there is evidence suggesting the involvement of inflammatory activity. Microglia, macrophage cells residing in the brain responsible for clearing external pathogens and dead cells, are of particular interest.Our study aims to investigate whether Lewy bodies …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Science
School
School of Biomedical Sciences
Research centre(s)

Centre for Microbiome Research

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