Dr Mark Wellard
Faculty of Science,
School of Chemistry & Physics
Biography
Research theme: Health, Food, Environment Research discipline: Chemistry Research program: Medical Physics Research areas Metabolite distributions in health and diseases such as schizophrenia, diabetes and prostate cancer: This work involves statistical analysis of complex data derived from NMR spectroscopic measurements of tissue, digests or biofluids to detect metabolite markers of disease. Characterization of isolated cartilage to increase the understanding of osteoarthritis: NMR is used to determine diffusion and relaxation behaviour in cartilage to determine structural changes associated with osteoarthritis. Utilising clinical MRI to determine changes in brain metabolite profiles associated with mental illness and diseases such as diabetes and epilepsy: Metabolite changes accompanying treatment are correlated with neuropsychological performance and other biological markers.Personal details
Positions
- Visiting Fellow
Faculty of Science,
School of Chemistry & Physics
Keywords
nuclear magnetic resonance spectroscopy (NMR), magnetic resonance imaging (MRI), metabonomics, HRMAS studies of tissue, cartilage structure and function, diabetes
Discipline
Medical Biotechnology, Clinical Sciences, Neurosciences
Field of Research code, Australian and New Zealand Standard Research Classification (ANZSRC), 2008
Qualifications
- Doctor of Philosophy - Victorian College of Pharmacy (The University of Melbourne)
Professional memberships and associations
International Society for Magnetic Resonance in Medicine
Australian and New Zealand Society for Magnetic Resonance
Australian and New Zealand Society for Magnetic Resonance
Selected publications
- Yusuf K, Momot K, Wellard R, Oloyede A, (2013) A study of the diffusion characteristics of normal, delipidized and relipidized articular cartilage using magnetic resonance imaging, Journal of Materials Science: Materials in Medicine, 24 (4), pp. 1005-1013.
- Radi B, Wellard R, George G, (2013) Effect of dangling chains on the structure and physical properties of a tightly crosslinked poly(ethylene glycol) network, Soft Matter, 9 (12), pp. 3262-3271.
- Pell G, Lin A, Wellard R, Werther G, Cameron F, Finch S, Papoutsis J, Northam E, (2012) Age-related loss of brain volume and T2 relaxation time in youth with Type 1 diabetes, Diabetes Care, 35 (3), pp. 513-519.
- O'Donoghue F, Wellard R, Rochford P, Dawson A, Barnes M, Ruehland W, Jackson M, Howard M, Pierce R, Jackson G, (2012) Magnetic resonance spectroscopy and neurocognitive dysfunction in obstructive sleep apnea before and after CPAP treatment, Sleep, 35 (1), pp. 41-48.
- Pope J, Wellard R, Momot K, (2011) Digital processing of diffusion-tensor images of avascular tissues. In G Dougherty, Medical Image Processing. Techniques and Applications, Springer, pp. 341-371.
- Wellard R, Jackson G, (2010) Magnetic resonance spectroscopy in seizure disorders. In PB Barker, JH Gillard & AD Waldman, Clinical MR Neuroimaging, Physiological and Functional Techniques (2nd Edition), Cambridge University Press, pp. 526-543.
- Momot K, Pope J, Wellard R, (2010) Anisotropy of spin relaxation of water protons in cartilage and tendon, NMR in Biomedicine, 23 (3), pp. 313-324.
- Yucel M, Wood S, Wellard R, Harrison B, Fornito A, Pujol J, Velakoulis D, Pantelis C, (2008) Anterior cingulate glutamate-glutamine levels predict symptom severity in women with obsessive-compulsive disorder, Australian and New Zealand Journal of Psychiatry, 42 (6), pp. 467-477.
- Berger G, Wood S, Wellard R, Profitt T, McConchie M, Amminger G, Jackson G, Velakoulis D, Pantelis C, McGorry P, (2008) Ethyl-eicosapentaenoic acid in first-episode psychosis. A 1H-MRS study, Neuropsychopharmacology, 33 (10), pp. 2467-2473.
- Scheffer I, Harkin L, Grinton B, Dibbens L, Turner S, Zielinski M, Xu R, Jackson G, Adams J, Connellan M, Petrou S, Wellard R, Briellmann R, Wallace R, Mulley J, Berkovic S, (2007) Temporal Lobe Epilepsy and GEFS+ Phenotypes Associated with SCN1B Mutations, Brain, 130 (1), pp. 100-109.
QUT ePrints
For more publications by Mark, explore their research in QUT ePrints (our digital repository).
Awards
- Type
- Committee Role/Editor or Chair of an Academic Conference
- Reference year
- 2008
- Details
- Committee member for the biennial conference of the Australian and New Zealand Society for Magnetic Resonance, held at Couran Cove, Queensland in 2009. I was on the organizing committee and also chaired a session at the conference.
- Type
- Membership of Learned Societies
- Reference year
- 2008
- Details
- Member of the student stipend committee, responsible for administering the travel awards made to students and conference participants from disadvantaged countries.
Research projects
- Title
- Mobility of Water in Cartilage as a Probe of Molecular Structure and Function
- Primary fund type
- CAT 1 - Australian Competitive Grant
- Project ID
- DP0880346
- Start year
- 2008
- Keywords
- Cartilage; Collagen and Proteoglycans; Osteoarthritis; Diffusion Tensor; Magnetic Resonance Imaging; Coarse Grained Simulations