QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 127 matching student topics
Displaying 61–72 of 127 results
Restoring adiponectin signalling to prevent prostate cancer progression
Advanced prostate cancer (PCa) is a leading cause of cancer-associated death in Australian men. Anti-androgens, which exploit the tumour’s reliance on androgens for its growth and spread, offer temporary remission in advanced PCa patients, but due to treatment resistance, fail to be curative. A further complication of anti-androgens is that they trigger a deleterious suite of metabolic side-effects resembling obesity/Metabolic syndrome. These symptoms not only impact patient health but promote the tumour to be more aggressive and resist treatment. Vital …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Targeting leptin's signalling axis to prevent treatment resistance in prostate cancer
Advanced prostate cancer (PCa) is a leading cause of cancer-associated death in Australian men. Anti-androgens, which exploit the tumour’s reliance on androgens for its growth & spread, offer temporary remission in advanced PCa patients, but due to treatment resistance, fail to be curative. A further complication of anti-androgens is that they trigger a deleterious suite of metabolic side-effects resembling obesity/Metabolic syndrome. These symptoms not only impact patient health but promote tumours to be more aggressive & resist treatment. Vital new …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
α-Synuclein–specific T-cell responses as early adaptive immune markers of Parkinson's disease
Parkinson’s disease develops over many years before motor symptoms become clinically apparent, limiting opportunities for early intervention. Increasing evidence suggests that adaptive immune responses, particularly T cells that recognise α-synuclein, may emerge during at-risk and early stages of disease.This project will investigate whether α-synuclein–specific T cells are expanded in at-risk individuals and early Parkinson's disease patients, with the goal of identifying early immune changes that may precede clinical disease onset.
- Study level
- Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Early innate immune signatures as biomarkers of Parkinson's disease onset
Parkinson's disease is typically diagnosed after the onset of motor symptoms, when significant neurodegeneration has already occurred. Growing evidence suggests that immune dysregulation, particularly within the innate immune system, may arise in the prodromal and early stages of disease and contribute to disease initiation.This project will investigate whether individuals in the prodromal and early stages of Parkinson's disease exhibit distinct peripheral immune signatures, focusing on monocyte and macrophage polarisation and plasma cytokine profiles, with the aim of identifying early immune …
- Study level
- Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Improving access to information and support for burn survivor communities
This PhD project will explore the information and support needs of people with lived experience of burn injuries, their families and communities. The project will focus on people with burn injuries once they leave hospital or when the majority of their burns have healed. The likely outcome of the project will be resources and strategies that help burn survivors, their families and communities access information and support which they have expressed is a high priority.
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Public Health and Social Work
- Research centre(s)
- Australian Centre for Health Services Innovation
Australian Centre for Health Services Innovation
Regenerating bone following osteosarcoma tumour resection in a post-chemotherapy treated bone defect
Osteosarcoma (OS) is the most common primary bone cancer in children and adolescents. Standard treatment involves surgical resection of the tumour combined with systemic chemotherapy. While most patients undergo limb-sparing surgery to avoid amputation, this often results in significant morbidity and lifelong complications. These complications stem from the creation of large bone defects, poor healing outcomes, the need for revision surgeries, and long-term prosthetic failureThere is a critical clinical need for regenerative strategies that restore bone integrity and function following …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Biomedical Technologies
Local drug delivery to prevent osteosarcoma recurrence and metastasis
Osteosarcoma (OS) is the most common primary bone cancer in children and adolescents. Despite aggressive treatment involving multi-agent chemotherapy and wide surgical resection, survival outcomes remain poor, with five year survival as low as 13% for patients with metastatic or recurrent disease. Current treatment relies heavily on systemic chemotherapy, which is associated with significant toxicity and long-term side effects, including cardiotoxicity, nephrotoxicity, and impaired growth and fertility. Local recurrence occurs in up to 30% of patients after surgical resection, often …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Biomedical Technologies
Monitoring Corneal Immune Cell Changes After Anti-Inflammatory and Immunosuppressant Eye Drops Using In Vivo Confocal Microscopy
This project investigates how corneal immune cells in the human eye respond to topical anti-inflammatory and immunosuppressant eye drops. By using in vivo confocal microscopy, we aim to monitor real-time cellular changes to better understand treatment effects in common ocular surface conditions.
- Study level
- Honours
- Faculty
- Faculty of Health
- School
- School of Clinical Sciences
- Research centre(s)
- Centre for Vision and Eye Research
Centre for Vision and Eye Research
International policy approaches to food sovereignty
This project will be a desktop document review of international policy preferences to food sovereignty.Food sovereignty is the right of peoples to health and culturally appropriate food produced through ecologically sound and sustainable methods, and their right to define their own food and agriculture systems. It incorporates the intergenerational transfer of cultural knowledge through food which is fundamental to maintaining identity, connectedness and traditional practices. The concept has traction in Canada, USA, and Aotearoa, but is only starting to gain …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Public Health and Social Work
Psycholinguistics and the neurobiology of language
Language is essential for human communication. However, there is still a lack of clarity about how the brain attains language. This knowledge is critical for understanding both healthy and disordered language production and comprehension (aphasia). Hence, there is a need for further exploration using psycholinguistic and neurolinguistic (neuroimaging, electrophysiology and brain stimulation) techniques.
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Psychology and Counselling
Multimodal AI to simulate medical student competency
The assessment of medical graduate competency is a cornerstone of medical education and a critical safeguard for patient safety. Newly qualified physicians must demonstrate a broad range of skills and knowledge, including diagnostic reasoning, clinical decision-making, communication, procedural skills, and professionalism before independently practicing medicine. Traditional assessment methods often include standardized multiple-choice examinations, objective structured clinical examinations (OSCEs), direct observation of procedural skills (DOPS), and portfolio reviews. While these methods offer valuable insights, they have inherent limitations. Standardized tests may …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Public Health and Social Work
- Research centre(s)
- Centre for Data Science
Bridging the gap: leveraging AI to improve healthcare access
Access to quality healthcare remains a significant challenge in many parts of the world, often due to geographic and financial barriers. This research explores how artificial intelligence (AI) can address the challenges of geographic and financial barriers in accessing healthcare. The project will focus on developing AI-powered solutions that enhance healthcare delivery, increase patient engagement, and reduce costs
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Public Health and Social Work
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