QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 639 matching student topics
Displaying 157–168 of 639 results
Characterise a novel DNA repair protein as a target for cancer therapies
Data generated in the lab has identified a novel DNA repair protein previously described as a key protein in HSP70/90 complexes. Many pathways of tumourigenesis are mediated by Heat Shock Proteins and HSP70/90 are found significantly upregulated in ovarian cancers. The targeting of HSP70/90 are an emerging therapeutic avenue for the treatment of ovarian cancer. Supporting this, an inhibitor of HSP90 has been shown to sensitise breast cancer cells to PARP inhibitors and paclitaxel.Our preliminary data indicates that this new …
- Study level
- Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Characterising the role of PARPs in DNA repair and cancer therapy
The genome of our cells is damaged multiple times each day, by various factors including sunlight and reactive oxygen species. In order for the DNA damage response to be efficient, our cells utilise highly coordinated repair pathways that function accurately and rapidly throughout the damaged cell. Cells that do not repair DNA damage correctly will accumulate damage and display increased genomic instability, which is a key hallmark of cancer cells, promoting their survival and rapid growth. DNA repair pathways are …
- Study level
- Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Restoring adiponectin signalling to prevent prostate cancer progression
Advanced prostate cancer (PCa) is a leading cause of cancer-associated death in Australian men. Anti-androgens, which exploit the tumour’s reliance on androgens for its growth and spread, offer temporary remission in advanced PCa patients, but due to treatment resistance, fail to be curative. A further complication of anti-androgens is that they trigger a deleterious suite of metabolic side-effects resembling obesity/Metabolic syndrome. These symptoms not only impact patient health but promote the tumour to be more aggressive and resist treatment. Vital …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Targeting leptin's signalling axis to prevent treatment resistance in prostate cancer
Advanced prostate cancer (PCa) is a leading cause of cancer-associated death in Australian men. Anti-androgens, which exploit the tumour’s reliance on androgens for its growth & spread, offer temporary remission in advanced PCa patients, but due to treatment resistance, fail to be curative. A further complication of anti-androgens is that they trigger a deleterious suite of metabolic side-effects resembling obesity/Metabolic syndrome. These symptoms not only impact patient health but promote tumours to be more aggressive & resist treatment. Vital new …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Modeling roost selection by flying foxes in Moreton Baty region
- Study level
- Honours
- Faculty
- Faculty of Business and Law
- School
- School of Accountancy
Voluntary assisted dying, medical practitioners and conscientious objection
Should legislation permitting Voluntary Assisted Dying (VAD) provide medical practitioners with a right to conscientiously object to VAD and, if so, what should the scope of that right be?Should it include a right not to give a person asking about VAD any information about it? In Victoria the legislation provides an unrestricted right to conscientiously object whereas in Western Australia the right to object is qualified by a requirement to give the patient information about VAD. Which position is most …
- Study level
- PhD
- Faculty
- Faculty of Business and Law
- School
- School of Law
- Research centre(s)
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Australian Centre for Health Law Research
Should Australia legislate to allow three parent babies?
In 2015, the United Kingdom legalised a form of in vitro fertilisation (IVF) therapy known as ‘three-parent IVF’ and, less colloquially, mitochondrial replacement therapy (MRT). This IVF procedure is aimed at enabling women who have mitochondrial diseases that would normally be passed down to their offspring to have a healthy child instead. The technique involves removing faulty mitochondria from the intended mother’s egg and replacing them with mitochondria from a generically unrelated woman (by transferring the intended mother's nucleus to …
- Study level
- PhD
- Faculty
- Faculty of Business and Law
- School
- School of Law
- Research centre(s)
-
Australian Centre for Health Law Research
Blast response and safety assessment of transport tunnels
Transport tunnels are important components of the transport systems in major cities. They can be vulnerable to bomb explosions caused by accidental or deliberate means.This project will evaluate the vulnerability of transport tunnels to credible blast events and the influence of key parameters. We'll then propose measures to mitigate the adverse effects of such explosions to maximise the safety of passengers, infrastructure and transport vehicles.
- Study level
- PhD
- Faculty
- Faculty of Business and Law
- School
- School of Accountancy
Consumer reactions to voice-based AI
Artificial intelligence increasingly allows marketers to manipulate video and audio materials in a manner that has been restricted to still pictures in the past. Yet little is known about how consumers engage with and react to marketing content that consumers know has been manipulated in this fashion. For instance, for whom, when and why do interactions with voice-based AI (e.g. Google Duplex, Healed through A.I.) reduce purchase intentions. Building on research from interpersonal interactions (Lechner & Mathmann, 2020) and motivational …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Business and Law
- School
- School of Advertising, Marketing and Public Relations
Enhancing the quality of teaching in Universities: Measuring the impact of professional development and recognition schemes (such as HEA Fellowship) on University Educators and Students
Enhancing the quality of teaching in Universities: Measuring the impact of professional development and recognition schemes (such as HEA Fellowship) on University Educators and Students
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Creative Industries, Education and Social Justice
- School
- School of Education
Curtailing corporate tax aggression through uncertain tax benefits
Over the last five years Australia has adopted numerous measures to address aggressive corporate tax practices. A recent addition to these measures (on the 1st of January 2019) is AASB Interpretation 23 - Uncertainty over Income Tax Treatments, which was developed to clarify the treatment of uncertain tax positions. This interpretation requires entities who produce general purpose financial reports (GPFRs) to disclose uncertain tax benefits (UTB) in the notes to their financial statements. Extant literature suggests that UTB disclosures are …
- Study level
- Honours
- Faculty
- Faculty of Business and Law
- School
- School of Accountancy
Understanding authenticity seeking in the purchase of indigenous art and souvenirs
There is a growing and substantial body of knowledge concerning tourists' perception of authenticity for indigenous art and souvenirs. Such products have significant impact on local economies.For tourists and visitors, indigenous art and souvenirs are mementos of their travel experiences and help tourists appreciate cross-cultural differences. However, more and more, these products are becoming mass-produced objects where the satisfaction of tourists and the profit motives of retailers are given priority. From the demand side, there are many motives for souvenir …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Business and Law
- School
- School of Advertising, Marketing and Public Relations
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