QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 479 matching student topics
Displaying 145–156 of 479 results
BIOM01 - Novel therapeutic strategies for targeting dementia
Dementia exhibits the presence of Lewy bodies in the cerebral cortex, which are composed of α-synuclein (αSYN) or Amyloid-β (Aβ) plaques, as well as hyperphosphorylated tau (P-tau) tangles in various forms of dementia. The exact pathological mechanisms underlying this disease are not well understood; however, there is evidence suggesting the involvement of inflammatory activity. Microglia, macrophage cells residing in the brain responsible for clearing external pathogens and dead cells, are of particular interest.Our study aims to investigate whether Lewy bodies …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Biomedical Sciences
- Research centre(s)
-
Centre for Microbiome Research
Experimental validation of a novel tricuspid valve design
The tricuspid valve is responsible for regulating the flow of blood between the right atrium and the right ventricle of the heart. During ventricular systole, it closes to prevent the backflow of blood from the right ventricle into the right atrium. This closure ensures that blood is pumped forward into the pulmonary circulation. In contrast, the tricuspid valve opens during ventricular diastole, allowing blood to flow from the right atrium into the right ventricle.When the tricuspid valve fails to close …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
- Centre for Biomedical Technologies
My flow: Menstrual cycle Femtech for elite athlete performance optimisation through wearable technology
There is a need for additional studies to monitor on-field performance parameters in female elite athletes (Meignié 2021). We know that wearable sensors can be used to monitor the physiological and biochemical profile of athletes (Seshadri 2019), and a combination of several wearables is going to be more effective for accessing all relevant parameters (Düking 2016). However, there is limited research on the effects of menstrual cycle phases on elite athlete performance (Meignié 2021).This proposed research aims to bridge the …
- Study level
- PhD
- Faculty
- Faculty of Creative Industries, Education and Social Justice
- School
- School of Design
- Research centre(s)
-
Design Lab
Elevating performance: Innovative design strategies for body-worn (diagnostic or biosensing) devices
How does technology help us to support a person’s sense of wellbeing and/or performance? Beyond technology and metrics, how do a body-worn (electronic/biosensing) device be designed to fit the person in different contexts of use and different performance needs? We are investigating the role of designing with sensor technology (sensor technology agnostic) in body-worn devices from a Human Centred (HCD) lens, and Research through Design (RtD) approach.In today's fast-paced world, the pursuit of optimal human performance has become a paramount …
- Study level
- PhD
- Faculty
- Faculty of Creative Industries, Education and Social Justice
- School
- School of Design
- Research centre(s)
-
Design Lab
Human biomarkers of stress, trauma, and memories of fear
Understanding how disorders such as posttraumatic stress disorder develop following trauma is a contemporary challenge for researchers in psychology. The best explanations involve a combination of psychological and biological factors that interact during and following trauma to create a range of troubling symptoms. This project will use cutting edge technology at QUT to provide insights into how a mix of biology and behaviour can result in exacerbated stress responses and threat memories in experimental and real-world settings.
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Psychology and Counselling
Human Emotional Learning: Likes, Dislikes and Fear
There is currently broad agreement that likes and dislikes, including strong emotional responses such as fear and anxiety, are learned. However, little is known about the manner in which different forms of emotional learning interact or about how emotional learning once acquired can be modified, reduced or eliminated. In particular in the context of fear learning this is problematic as fear memories once acquired seem difficult to change and likely to return even after successful extinction – a phenomenon known …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Psychology and Counselling
Board interlocks and firm decisions
Board interlocks research is one of the most vibrant areas in corporate governance research. A board interlock is a tie created by two firms sharing a common director. In other words, a director can hold multiple directorships in more than one firm. Board interlocks reflect complex inter-organisational relationships which play an important role in determining a firm’s strategies and structures.Prior research finds that board interlocks have an impact on reducing environmental uncertainty, gaining access to diverse and unique information, diffusing …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Business and Law
- School
- School of Accountancy
Designing smart cities for more-than-human futures
Cities are changing across the globe. Climate change, rapid urbanisation, pandemics, as well as innovations in technologies such as blockchain, AI and IoT are all impacting urban space. One response to such changes has been to make cities ecologically sustainable and 'smart'. The 'eco smart city', for instance, uses networked sensing, cloud and mobile computing to optimise, control, and regulate urban processes and resources. From real-time bus information, autonomous electric vehicles, smart parking, and smart street lighting, such initiatives are …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Creative Industries, Education and Social Justice
- School
- School of Design
- Research centre(s)
-
Design Lab
Characterising drivers of melanoma cell heterogeneity
Tumour cell heterogeneity is linked to tumour progression through the generation of divergent cellular behaviours such as proliferation, survival, invasion and therapy resistance. Crucially, conventional and targeted therapies generally only target highly proliferative cells in tumours leading to initial tumour regression, however alternative sub-populations underpin the return of treatment refractory disease and facilitate metastatic spread. Our laboratory is focused on understanding the regulatory drivers of cellular plasticity in melanoma to better understand progression and metastatic spread of this disease and …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Characterisation of a novel protein co-amplified with the n-MYC oncogene
The MYCN oncogene is amplified in a number of tumour types, including Neuroblastoma (NB) and Neuroendocrine Prostate Cancer (NEPC), where it is associated with worse patient prognosis, as compared to non-amplified tumours. However, the high expression of MYCN (encoding the n-MYC protein) alone in non-amplified tumours is associated with better patient prognosis and less aggressive disease. This suggests that other genes co-expressed in MYCN amplified tumours may be responsible for mediating the aggressive traits of n-MYC. Our team has identified …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Genomics and Personalised Health
Characterisation of emerging multidrug resistant E. coli pathogens
The last fifteen years have witnessed an unprecedented rise in the rates of antimicrobial resistance among Gram-negative bacteria, described by the World Health organisation as a global health crisis (1). Escherichia coli sequence type 131 (E. coli ST131) is a ‘high-risk’ group of Gram-negative pathogens that have emerged rapidly and spread worldwide in the period of the last 10 years (2). E. coli ST131 strains are typically resistant to multiple classes of antibiotics and cause bloodstream and urinary tract infections …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Smart electrochemical aptamer biosensors for continuous monitoring cell health and function
Microphysiological systems including organ-on-chip platforms and 3D tissue models are transforming how we study human biology, enabling advanced in vitro models for tissue regeneration and drug testing that are far more physiologically relevant than conventional cell culture. The critical challenges for mass production, quality control, tracking their health and function in advanced in vitro models still remain. Monitoring cell health and function in these systems still relies on destructive or invasive methods, requiring cell sacrifice or physical sampling at a …
- Study level
- PhD
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
- Centre for Biomedical Technologies
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