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Found 3 matching student topics

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Estimating the evolutionary history of plasmids and viruses

In the case of cellular life - bacteria, archaea and eukaryotes - determining the 'tree of life' is a comparatively well-studied problem.This vertical evolutionary history can be estimated using concatenated gene phylogenies, where single copy marker genes are concatenated into a single multiple sequence alignment which is then used in a phylogenetic tree reconstruction algorithm.Viral genomes and plasmid sequences, meanwhile, are more challenging to fit into a phylogenetic framework.

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)

Centre for Microbiome Research

Early innate immune signatures as biomarkers of Parkinson's disease onset

Parkinson's disease is typically diagnosed after the onset of motor symptoms, when significant neurodegeneration has already occurred. Growing evidence suggests that immune dysregulation, particularly within the innate immune system, may arise in the prodromal and early stages of disease and contribute to disease initiation.This project will investigate whether individuals in the prodromal and early stages of Parkinson's disease exhibit distinct peripheral immune signatures, focusing on monocyte and macrophage polarisation and plasma cytokine profiles, with the aim of identifying early immune …

Study level
Master of Philosophy
Faculty
Faculty of Health
School
School of Biomedical Sciences

Phase separation and atmospheric water exchange in droplet nuclei

Several PhD positions are available for motivated individuals to investigate phase separation and glassy state formation inside airborne droplet nuclei and its impact on water uptake and loss during atmospheric transport.Marine and continental atmospheric aerosols play an important role in the global climate hydrological cycle while respiratory aerosols released during breathing speech and coughing are responsible for the airborne transmission of human respiratory viral infections such as SARS-CoV-2. These processes can limit the availability of cloud seeding nuclei with implications …

Study level
PhD, Master of Philosophy
Faculty
Faculty of Science
School
School of Earth and Atmospheric Sciences

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