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Found 3 matching student topics

Displaying 1–3 of 3 results

Separating nonlinear optical effects in optical limiters

Optical limiting uses a medium’s nonlinear response to allow light at low intensities to be transmitted, but restricts transmission at high intensities so as to safeguard sensitive detectors including the eye. A popular nonlinear process used in optical limiters is two photon absorption where two high intensity light photons are simultaneously absorbed thereby reducing the light transmission through the medium. Unfortunately, in gold nanoparticle optical limiters a second nonlinear process can arise – saturated absorption which leads to an increase …

Study level
Honours, Vacation research experience scheme
Faculty
Faculty of Science
School
School of Chemistry and Physics
Research centre(s)
Centre for Materials Science

QIMR02 - Targeting breast cancer and metastasis by oligonucleotide therapeutics with lipid nanoparticle (LNP) delivery system

Cancer is the second leading cause of death worldwide. The major cause of cancer-related mortality (~90%) is due to metastasis. Breast cancer (BC) is the most commonly diagnosed cancer among women. Of the 10,000 Australians that live with metastatic breast cancer only 32% are alive after 5-years (relative survival-rate).While current cancer treatments mostly focus on targeting the primary tumours, the treatment or prevention of metastasis continues to have limited success. We have shown genetic inhibition of Cep55 reduces cancer progression …

Study level
Vacation research experience scheme
Faculty
Faculty of Health
School
School of Biomedical Sciences

Traces of zinc and ciprofloxacin loaded polymer nanoparticulate inhaled formulations against lung infections associated with COPD and CF (CLIN08)

Lower respiratory tract infections (LRTIs) are one of the fatal diseases of the lungs that have severe impacts on public health, especially for Indigenous people. The currently available antibiotics administered orally for the treatment of LRTIs need high doses with frequent administration and cause dose-related adverse effects. To overcome this problem, we will investigate the development of ciprofloxacin (CIP) loaded poly(2-ethyl-2-oxazoline) (PEtOx) nanoparticles (NPs) with traces of zinc for potential pulmonary delivery from dry powder inhaler (DPI) formulations. As zinc …

Study level
PhD
Faculty
Faculty of Health
School
School of Clinical Sciences
Research centre(s)

Centre for Immunology and Infection Control

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