QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 3 matching student topics
Displaying 1–3 of 3 results
Patient-derived oncology NAMs for preclinical breast cancer research and therapeutic evaluation
New approach methodologies (NAMs), including advanced 3D cultures and microphysiological systems (MPS), are creating new opportunities to develop more human-relevant approaches for preclinical cancer research. However, translating these technologies from established cell lines to patient-derived tumours remains challenging because of limited tissue availability, tumour heterogeneity and variability in model establishment and performance.Building on established QUT expertise in patient-derived bioengineered breast tumour models, this project will develop robust and reproducible patient-derived oncology NAMs for preclinical breast cancer research and therapeutic evaluation.Breast …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Biomedical Technologies
Automation-enabled microphysiological systems for multicellular oncology NAMs
New approach methodologies (NAMs), including microphysiological systems (MPS), are transforming preclinical cancer research by providing human-relevant alternatives to conventional preclinical models. However, increasing the biological complexity of these models also creates major challenges in reproducibility, scalability and experimental throughput.Oncology provides a compelling application for addressing these challenges. Tumours are complex tissues in which cancer cells interact dynamically with extracellular matrix, immune cells, vascular cells and other components of the tumour microenvironment. Reproducing these interactions in vitro requires technologies that can …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Biomedical Technologies
Smart electrochemical aptamer biosensors for continuous monitoring cell health and function
Microphysiological systems including organ-on-chip platforms and 3D tissue models are transforming how we study human biology, enabling advanced in vitro models for tissue regeneration and drug testing that are far more physiologically relevant than conventional cell culture. The critical challenges for mass production, quality control, tracking their health and function in advanced in vitro models still remain. Monitoring cell health and function in these systems still relies on destructive or invasive methods, requiring cell sacrifice or physical sampling at a …
- Study level
- PhD
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
- Centre for Biomedical Technologies
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