QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.

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Found 639 matching student topics

Displaying 397–408 of 639 results

Genome to phenome: exploiting multi-omics and deep learning strategies to decipher importance of isoforms in health and behaviour

The molecular process that leads to multiple mRNA transcripts being produced from the same segment of DNA (aka gene) is known as alternative splicing (AS). This is a common form of regulation in higher eukaryotes, enabling the production of novel protein isoforms, which in turn are known to have a big impact on phenotype. Understanding the regulatory factors involved in AS, including epigenetic mechanisms such as DNA methylation, will offer key insights into important biological phenomena (health disease, behaviour, production). …

Study level
PhD
Faculty
Faculty of Science
School
School of Biology and Environmental Science

Preventing arterial catheter-related harm in intensive care

Each year more than 200,000 patients (adults and children) are admitted to intensive care units (ICU) in Australia and New Zealand for treatment of serious and life-threatening injury or illness, or recovery from major surgery. The vast majority (~90%) of ICU patients will require an arterial catheter during their admission to optimise vital treatment and monitoring. Arterial catheters are small hollow plastic tubes inserted into peripheral arteries to facilitate continuous haemodynamic monitoring (e.g. blood-pressure) and frequent blood sampling. Hence, effective …

Study level
PhD, Master of Philosophy
Faculty
Faculty of Health
School
School of Nursing
Research centre(s)
Centre for Healthcare Transformation

Prescriptive process analytics

With growing significance of data there is a need to harness the potential of that data for improved business operations. Historical data is often to provide a descriptive overview of how business processes have performed in the past. However, there is a need to be proactive and take appropriate actions to ensure that business processes perform in an optimal manner. Prescriptive analytics is a process that analyzes data and provides instant recommendations on how to optimize business practices. Prescriptive analytics …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Science
School
School of Information Systems

Human biomarkers of stress, trauma, and memories of fear

Understanding how disorders such as posttraumatic stress disorder develop following trauma is a contemporary challenge for researchers in psychology. The best explanations involve a combination of psychological and biological factors that interact during and following trauma to create a range of troubling symptoms. This project will use cutting edge technology at QUT to provide insights into how a mix of biology and behaviour can result in exacerbated stress responses and threat memories in experimental and real-world settings.

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Psychology and Counselling

Microfluidic chip-based tumor-immune cancer models for biomarker discovery

In-vitro profiling of tumour-immune cell interactions in proximity can provide valuable insight into patient response to new combinatorial immunotherapies that are in the pipeline and currently being tested in clinical trials. These in-vitro models allow for a more controlled and isolated environment and provide a methodical approach for generating quantifiable data characterizing the interactions between target and effector cells. Traditionally executed in well-plates, tumour-immune models have been slowly moving towards a microfluidic chip-based approach for several reasons: better control over …

Study level
PhD, Master of Philosophy
Faculty
Faculty of Engineering
School
School of Mechanical, Medical and Process Engineering
Research centre(s)
Centre for Biomedical Technologies

Ubiquitous visual positioning devices

Everything that moves is defined and limited by its ability to navigate the world in which it exists. Knowing where you are located in the world is a key navigational capability for people, animals, and both autonomous and human-operated platforms ranging from self-driving cars to aircraft.But accurate and trustworthy positional knowledge has widespread potential implications beyond navigation: it can, for example, allow life-and-death decisions in defence and in tracking the spread of global pandemics. Both the potential of and problems …

Study level
Honours
Faculty
Faculty of Engineering
School
School of Electrical Engineering and Robotics
Research centre(s)
Centre for Robotics

Ecosystem responses to climate change and human impacts on sub-Antarctic islands: a context for conservation

Sub-Antarctic islands have unique ecosystems and landscapes under increasingly pressure from climate change. In many cases this is compounded by the introduction of invasive species since their discovery by humans in the 1800s.Understanding ecosystem and environmental responses to climate change and separating them from human-induced causes of change is essential for their future protection. To do this requires quantifying long-term, natural rates and variability of change, establishing the ‘baseline’ status of ecosystems and the environment prior to human arrival, and …

Study level
PhD
Faculty
Faculty of Science
School
School of Biology and Environmental Science
Research centre(s)

Centre for the Environment

Assessing visual acuity errors in pre-school children (CVER01)

Measuring visual acuity is in preschool children is challenging. In particular, young children will be prone to making mistakes in identifying symbols on eye charts, even when they can see what those symbols are, so called “false negative responses”.This project uses an established vision assessment protocol, EVA testing, and assesses the extent of false negative responses in this task. The protocol assesses the effects of an intervention, pointing to the target on a card, which may decrease false negative responses. …

Study level
PhD
Faculty
Faculty of Health
School
School of Clinical Sciences
Research centre(s)

Centre for Vision and Eye Research

Scheduling of vessel movements in channel constrained ports

International trade is heavily reliant on maritime transportation which constitutes 80% of total volume. Ports have a significant impact on the efficiency of maritime transportation, with significant delays to vessels observed in accessing or departing ports. These delays can be a result of constraints on wharf capacity, channel capacity, access to tugs and pilots, or a combination of these factors. This project will focus on the development of novel operations research techniques to optimise the efficiency of scheduling vessel movements …

Study level
PhD, Master of Philosophy
Faculty
Faculty of Science
School
School of Mathematical Sciences
Research centre(s)
Centre for Data Science

The effects of trust on government operations

For a government to operate efficiently, the trust of its constituents, as well as the global community, is considered to be of substantial importance. A lack of trust could impair the government’s ability to effectively manage and fund its operations from collecting taxes and external investment. However, further research is required to understand the underlying trust mechanisms and their influence on governments’ performance. To address this research gap, the project will examine how trust in government is determined, evaluate how …

Study level
PhD, Master of Philosophy
Faculty
Faculty of Business and Law
School
School of Accountancy
Research centre(s)
Centre for Future Enterprise

Antibiotic-loaded polymer nanoparticulate inhaled formulations against lung infections associated with COPD and CF

Lower respiratory tract infections (LRTIs) are one of the fatal diseases of the lungs that have severe impacts on public health especially the Indigenous people. The currently available antibiotics administered orally for the treatment of LRTIs need high doses with frequent administration and cause dose-related adverse effects.To overcome this problem, we will investigate the development of antibiotic-loaded polymer nanoparticles (NPs) for potential pulmonary delivery from dry powder inhaler (DPI) formulations. This study will address the release profile of the antibiotic …

Study level
PhD
Faculty
Faculty of Health
School
School of Clinical Sciences
Research centre(s)
Centre for Materials Science
Centre for Immunology and Infection Control

Identifying Indigenous contributions to knowledge

The Australian Census collects data every ten years to reflect who we are as a nation. But the data collected by the Census only tells part of our story.Indigenous people lived in Australia for thousands of years before the arrival of European settlers, accumulating a wealth of knowledge about Australia's land, climate, flora and fauna. Researchers have only begun tapping this knowledge as the basis for modern scientific research.This project will combine machine learning and text-analytics tools to develop a …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Science
School
School of Mathematical Sciences
Research centre(s)
Centre for Data Science

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