QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 114 matching student topics
Displaying 73–84 of 114 results
Development of a Microfluidic Gut-Brain Axis Chip
The gut microbiome refers to the collection of micro-organisms that are living symbiotically in the human or animal gastrointestinal tract (defined as the “microbiota”), their genetic material as well as the surrounding environmental habitat. It is now appreciated that the microbiome plays an important role in human health and diseases. Many neurodegenerative diseases, such as Parkinson's Disease have been linked to dysregulation of the gut microbiota. However, it is difficult to study gut-brain axis using animal models due to inter-species …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
- Centre for Biomedical Technologies
Centre for Microbiome Research
Microfluidic chip-based tumor-immune cancer models for biomarker discovery
In-vitro profiling of tumour-immune cell interactions in proximity can provide valuable insight into patient response to new combinatorial immunotherapies that are in the pipeline and currently being tested in clinical trials. These in-vitro models allow for a more controlled and isolated environment and provide a methodical approach for generating quantifiable data characterizing the interactions between target and effector cells. Traditionally executed in well-plates, tumour-immune models have been slowly moving towards a microfluidic chip-based approach for several reasons: better control over …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
- Centre for Biomedical Technologies
Simulation of turbulent fluid flow through a microfluidic device using CFD
Microfluidic devices (MFD) are extensively used in microbial studies. Bacterial cell attachment onto surfaces under flow conditions in laminar regime has been previously studied using a custom designed MFD.As an extension of this study, microbial attachment under turbulent flow is to be studied in a future project. The suitability of current MFD for microbial studies under turbulent flow must be evaluated to adopt / redesign the MFD.A computational fluid dynamics (CFD) analysis is proposed to examine the fluid flow inside …
- Study level
- Honours
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
Engineering the prostate tumour microenvironment in organ-on-a-chip systems
Prostate cancer remains one of the leading causes of global death. The tumour microenvironment (TME) including blood vessels, immune cells, fibroblasts, and the extracellular matrix (ECM) possesses disease-specific biophysical and biological factors that are difficult to recapitulate using conventional in vitro cell culture models.The absence of these factors, however, causes cells to display abnormal morphologies, polarisation, proliferation, and drug responses, thereby limiting the ability to translate research findings from traditional cell culture into clinical practice.Recent advances in organ-on-a-chip technology enable …
- Study level
- Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Growth and characterisation of epitaxial graphene for electronic and sensing applications
The extraordinary properties of graphene, a single sheet of carbon atoms (e.g. monodimensional structure, high conductivity, low-noise characteristics) are expected to be exploited in the next generation of electronic devices and gas sensors. These applications require a perfect control of the growth of graphene layers, and an optimum integration with the processes and materials used in the semiconductor industry.This project aims at studying the growth of graphene obtained by heating crystalline SiC at high temperature in Ar atrmosphere and ultra …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Chemistry and Physics
- Research centre(s)
- Centre for Materials Science
Legal, multidisciplinary and public health research regarding child abuse and neglect
Professor Ben Mathews is an internationally recognised expert in multiple legal areas connected with child abuse and neglect. These include sexual abuse generally, physical abuse and corporal punishment, domestic violence, civil claims for child abuse, statutes of limitation, mandatory reporting laws, institutional child abuse, child protection systems, criminal prosecution, prevention, regulation and oversight, public health and public health law analyses, and children's rights. Ben welcomes all enquiries about topics connected with these themes.In addition, he is currently leading the Australian …
- Study level
- PhD
- Faculty
- Faculty of Business and Law
- School
- School of Law
- Research centre(s)
-
Australian Centre for Health Law Research
Promoting incidental physical activity and social interactions in public space
The World Health Organisation recently raised the alarm on the critical importance of physical activity and social interactions for mental and physical health, highlighting the need for active environments that support people to engage in healthy activities. In order to address the high-rates of physical inactivity and social isolation, we need additional research evidence to design high-quality public spaces that promote health and wellbeing for all ages. This study lies at the intersection of built environment, human behaviour, and health …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Engineering
- School
- School of Architecture and Built Environment
Advanced numerical modelling to study fluid flow and heat transfer of ground-mounted photovoltaic panels for the power generation industry
The increase in global energy demand necessitates further advancement in photovoltaic (PV) systems. Advancements in PVs could potentially play a role to help meet the Paris Agreement of limiting global temperature increase to below 2°C.The performance of ground-mounted PV panels commonly found in solar farms depends on a myriad of factors such as tilt angle, microclimate i.e. wind loads, shading, solar irradiance, and dust deposition. This project aims to develop an advanced numerical model, namely computational fluid dynamics (CFD), backed …
- Study level
- PhD, Honours
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
Image-based assessment of atherosclerotic plaque vulnerability: Towards a computational tool for early detection and prediction
Plaque characteristics and local haemodynamic/mechanical forces keep changing during plaque progression and rupture.Quantifying these changes and discovering the progression-stress correlation can improve our understanding of plaque progression/rupture. This will lead to a quantitative assessment tool for early detection of vulnerable plaques and prediction of possible ruptures.Our research project aims to combine medical imaging, computational modelling, phantom experiments and pathological analysis to investigate plaque progression and vulnerability to rupture in both animal models and patients with carotid stenosis.We will identify and …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
- Centre for Biomedical Technologies
Image-based computational model to predict intracranial aneurysm rupture
Intracranial aneurysms are bulging, weak areas of an artery that supply blood to the brain which are relatively common. While most aneurysms do not show symptoms, 1% spontaneously rupture which can be fatal or it can leave the survivor with permanent disabilities. This catastrophic outcome has motivated surgeons to operate on approximately 30% of aneurysms despite their rate of complications arising and cost of operation.The impact of aneurysm morphology on blood flow shear stress and rupture could educate surgical decision-making …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
- Centre for Biomedical Technologies
Regenerating bone following osteosarcoma tumour resection in a post-chemotherapy treated bone defect
Osteosarcoma (OS) is the most common primary bone cancer in children and adolescents. Standard treatment involves surgical resection of the tumour combined with systemic chemotherapy. While most patients undergo limb-sparing surgery to avoid amputation, this often results in significant morbidity and lifelong complications. These complications stem from the creation of large bone defects, poor healing outcomes, the need for revision surgeries, and long-term prosthetic failureThere is a critical clinical need for regenerative strategies that restore bone integrity and function following …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Biomedical Technologies
Novel tricuspid valve design and heart pump
Without proper treatment, patients with tricuspid valve regurgitation are at high risk for developing lethal complications, including heart failure or atrial fibrillation (AFib), and disorder heart's rhythm. Currently, open chest surgery is commonly performed to address tricuspid regurgitation. Therefore, there is an urgent need for an alternative approach involving the design of a transcatheter tricuspid valve. This valve is intended to be inserted through minimally invasive techniques, potentially eliminating the need for open chest surgery.This project aims to validate the …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
- Centre for Biomedical Technologies
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