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Quantifying oxygen tolerance in a climate-relevant ecosystem using machine learning

Aims and methodologyPermafrost thaw induced by climate change is predicted to make up to 174 Pg of near-surface carbon (less than 3m below the surface) available for microbial degradation by 2100. Despite having major implications for human health, prediction of the magnitude of carbon loss as carbon dioxide (CO2) or methane (CH4) is hampered by our limited knowledge of microbial metabolism of organic matter in these environments. Genome-centric meta-omic analysis of microbial communities provides the necessary information to examine how …

Study level
Vacation research experience scheme
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)

Centre for Microbiome Research

Electrothermal film heaters

Flexible electrothermal heaters have attracted a growing interest because of their broad applications in wearable electronics, including warming garments, and as flexural warmers for medical devices and vehicles. Traditional electrothermal materials such as ferro chromium (FeCr)-based alloys have disadvantages such as heavy weight, rigidity and low heating efficiency. Indium tin oxide (ITO) is widely used in commercial products due to its high transparency and high electrical conductivity. However, the finite reserve of indium has resulted in an increasing price of …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Science
School
School of Chemistry and Physics

Engineering response to climate emergency with zero carbon footprint for building construction by 2030 using circular economy principles

We as engineers can make a contribution to address the current climate emergency.The Australian Sustainable Built Environment Council report (2016) found that if Australia's built environment sector reaches zero carbon emissions for the operation of residential and commercial buildings by 2050, it could contribute 28% to the country's 2030 emissions reduction target and save up to AU$20 billion.In this project we will consider the application of the circular economy, which is based on the principles of designing out waste and …

Study level
PhD, Honours, Vacation research experience scheme
Faculty
Faculty of Engineering
School
School of Civil and Environmental Engineering
Research centre(s)
Centre for Materials Science
Centre for a Waste-Free World

Identifying emergent ecosystem responses through genes-to-ecosystems integration at Stordalen Mire

Permafrost thaw induced by climate change is predicted to make up to 174 Pg of near-surface carbon (less than 3m below the surface) available for microbial degradation by 2100. Despite having major implications for human health, prediction of the magnitude of carbon loss as carbon dioxide (CO2) or methane (CH4) is hampered by our limited knowledge of microbial metabolism of organic matter in these environments.Genome-centric meta-omic analysis of microbial communities provides the necessary information to examine how specific lineages transform …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)

Centre for Microbiome Research

Carbonate Sediment dynamics from the Southern Great Barrier Reef Coral Sea

The southern extent of the modern Great Barrier Reef (GBR) marks the transition from tropical to subtropical ocean conditions. The shelf edge and upper slope in this vast area of the southern GBR were poorly mapped when compared to the north. Very little systematic multibeam seafloor mapping had been done in the southern GBR with most datasets collected opportunistically while in transit.New bathymetry, backscatter data, and sediments samples extend our understanding of eastern Australia’s palaeoshorelines and provide a basis for …

Study level
Vacation research experience scheme
Faculty
Faculty of Science
School
School of Earth and Atmospheric Sciences
Research centre(s)

Centre for the Environment

Metabolic diversity of the anaerobic methanotrophic (ANME) archaea mediating methane oxidation in freshwater environments

The as-yet-uncultured archaeal lineage Methanoperedenaceae are anaerobic methanotrophs with a key role in mitigating the atmospheric release of methane in freshwater environments. The metabolic diversity of these microorganisms directly links methane with several key biochemical cycles and suggests a remarkable ability of these microorganisms to adapt to diverse environmental conditions.The overall aims for a potential Honours/MSc project will be to uncover the metabolic diversity of the Methanoperedenaceae and to understand the evolutionary mechanisms responsible for these adaptations.

Study level
Master of Philosophy, Honours, Vacation research experience scheme
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)

Centre for Microbiome Research

Post-translational modification of proteins in cancer

The Protein Ablation Cancer Therapeutics (PACT) laboratory are interested in understanding how post-translational modifications contribute to the tumorigenic functions of proteins in cancer cells. We hypothesise that particular post-translational modifications are required for the cancer-associated function of a protein and that prevention of these would be a useful approach to treating cancer.The aim of this project is to select a candidate protein from our database of potential targets, confirm the protein is modified, identify the key modified lysine in the …

Study level
PhD, Master of Philosophy, Honours, Vacation research experience scheme
Faculty
Faculty of Health
School
School of Biomedical Sciences

High performance and economical adsorbents for carbon capture

Capturing excess CO2 from the atmosphere or anthropogenic emissions is key to minimising a warming climate. However, a major barrier to implementing carbon capture is the cost associated with current technologies. Therefore, development of high performance and economical materials to capture excess carbon is of great interest.

Study level
Honours, Vacation research experience scheme
Faculty
Faculty of Engineering
School
School of Mechanical, Medical and Process Engineering

Using a natural β-carboline dimer compound to target metabolic vulnerabilities linked to glycolysis in prostate cancer

Prostate cancer is an androgen dependent cancer and treatments are aimed at preventing activation of the androgen receptor. Part of the development of resistance to therapies involves prostate cancers reprogramming their metabolism to overcome metabolic stress induced by these therapies and support growth and survival. This reprogramming involves increases in the rate of glycolysis and intermediate pathways branching from glycolysis. Previously in our laboratory, the natural compound, beta-carboline dimer, BD, was identified to have potent effects on cell viability, cell …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

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