QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 6 matching student topics
Displaying 1–6 of 6 results
Engineering Chimeric Antigen Receptor (CAR) T cell for the treatment of cancer
Chimeric Antigen Receptor (CAR) T cells are genetically modified immune cells that can recognise and kill cancer cells. They do so through the CAR, which recognises specific antigens expressed on cancer cells. CAR T cell therapy has emerged as an effective form of cancer immunotherapy in certain types of blood cancers and are now approved for use in patients. However, CAR T cell therapy can only benefit a very small proportion of cancer patients at present because it is very …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Analysis of polyphenol oxidases (PPOs) during banana ripening
Polyphenol oxidases (PPOs) are a group of copper-containing enzymes naturally present in many fruit including bananas. They play a role in the browning or discoloration of fruit when they are cut, bruised, or exposed to air. The browning reaction they catalyse can affect the visual appeal, taste, and quality of certain fruit, leading to consumer dissatisfaction and reduced market value.The disruption of genes involved in PPO production in plants leads to a reduction or elimination in enzyme activity resulting in …
- Study level
- Vacation research experience scheme
- Faculty
- Faculty of Science
- School
- School of Biology and Environmental Science
- Research centre(s)
- Centre for Agriculture and the Bioeconomy
Modelling the deformation of bacteria on nanopatterned surfaces
The antibacterial mechanism of nanopatterned surfaces promises to be a valuable tool in the fight against implant infection, fomite transmission and antibiotic resistance. This mechanism is principally physical in nature, arising from the deformation of the bacterial envelope upon contacting the nanopatterned surface.To enhance understanding of the mechanism, this project will involve modelling the deformation of gram-negative and gram-positive bacterial envelopes using finite element analysis in ABAQUS. The key aims of the modelling are to identify locations of critical stress/stress …
- Study level
- Vacation research experience scheme
- Faculty
- Faculty of Engineering
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
- Centre for Biomedical Technologies
Centre for Biomedical Technologies
Hearing colour and seeing sound – switchable optoacoustic imaging agents
Optoacoustic imaging is a relatively new medical imaging technique. It utilises laser light to excite an imaging agent, which in turn converts this light energy into heat. This heat is dissipated as a sound wave, which can be detected with an ultrasound receiver. This technique aims to overcome the minimal penetration depth of fluorescence imaging, and the lack of molecular specificity of ultrasound.In this project we are aiming to develop and synthesize intelligent imaging agents for optoacoustics, which are able …
- Study level
- Master of Philosophy, Honours, Vacation research experience scheme
- Faculty
- Faculty of Science
- School
- School of Chemistry and Physics
- Research centre(s)
- Centre for Materials Science
Exploring chemotherapy-induced molecular aging and its relationship to exercise
Ovarian cancer is the sixth most common cause of death from cancer in women, with a five-year survival rate of less than 45 per cent. However, there is emerging research that shows the benefits of exercise therapy during recovery following certain cancer treatments, and how exercise can improve and extend the lives of women with ovarian cancer.This project is a collaboration exploring these health and survival outcomes in ovarian and other gynaecological cancers, and in particular how new diagnostic testing …
- Study level
- Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
QIMR02 - Targeting breast cancer and metastasis by oligonucleotide therapeutics with lipid nanoparticle (LNP) delivery system
Cancer is the second leading cause of death worldwide. The major cause of cancer-related mortality (~90%) is due to metastasis. Breast cancer (BC) is the most commonly diagnosed cancer among women. Of the 10,000 Australians that live with metastatic breast cancer only 32% are alive after 5-years (relative survival-rate).While current cancer treatments mostly focus on targeting the primary tumours, the treatment or prevention of metastasis continues to have limited success. We have shown genetic inhibition of Cep55 reduces cancer progression …
- Study level
- Vacation research experience scheme
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
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