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Found 3 matching student topics

Displaying 1–3 of 3 results

Using a natural β-carboline dimer compound to target metabolic vulnerabilities linked to glycolysis in prostate cancer

Prostate cancer is an androgen dependent cancer and treatments are aimed at preventing activation of the androgen receptor. Part of the development of resistance to therapies involves prostate cancers reprogramming their metabolism to overcome metabolic stress induced by these therapies and support growth and survival. This reprogramming involves increases in the rate of glycolysis and intermediate pathways branching from glycolysis. Previously in our laboratory, the natural compound, beta-carboline dimer, BD, was identified to have potent effects on cell viability, cell …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

Identifying protein and metabolite markers of burn injury and trauma

It can be difficult for clinical teams to determine the severity of burn injuries when the patient first presents to the hospital. This is because burn wounds continue to deepen/progress over time, in a process known as burn wound conversion. Some wounds may deepen over days or weeks and require aggressive surgical treatment e.g. grafting, and some wounds don’t progress, stay superficial in depth, and they can be managed conservatively with the application of different bandages or dressings. We have …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

Exploding shallow marine volcanoes: investigating the petrology of the 2019 pumice raft-producing eruption from Volcano 0403-091, Tonga

More than 21,000 km of submarine volcanoes front subduction zones, many of which lie in shallow water close to inhabited areas. Eruptions at these volcanoes can be explosive and may have significant impacts on nearby communities, or generate pumice rafts that prolong impact at remote locations. For the first time, samples of a shallow marine explosive eruption have been collected from the buoyant pumice raft and from the seafloor at the vent of Volcano 0403-091, Tonga.

Study level
PhD, Master of Philosophy
Faculty
Faculty of Science
School
School of Earth and Atmospheric Sciences
Research centre(s)
Centre for Materials Science
Centre for the Environment

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