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Found 18 matching student topics

Displaying 1–12 of 18 results

How do healthy people sleep? Biomechanics, physiology, and environment - what matters most?

In the Westernized world a person typically spends one third of their life in bed, with more time spent sleeping in a bed than in any other single activity. Sleep amount and quality of sleep have a direct impact on mood, behaviour, motor skills and overall quality of life. Yet, despite how important restful sleep is for the body to maintain good health, there is a comparatively small amount of studies evaluating key multi-factorial and biomechanical determinants of restful sleep …

Study level
PhD
Faculty
Faculty of Engineering
School
School of Mechanical, Medical and Process Engineering
Research centre(s)
Centre for Biomedical Technologies

Predicting good sleep using computer science: Can we use machine learning to find out 'what's the best bed?'

In the Westernised world a person typically spends one third of their life in bed, with more time spent sleeping in a bed than in any other single activity. Sleep amount and quality of sleep have a direct impact on mood, behaviour, motor skills and overall quality of life. Yet, despite how important restful sleep is for the body to maintain good health, there is a comparatively small amount of studies evaluating key multi-factorial determinants of restful sleep in non-pathological, …

Study level
PhD
Faculty
Faculty of Engineering
School
School of Mechanical, Medical and Process Engineering
Research centre(s)
Centre for Biomedical Technologies

Optimisation of piezoelectric materials for robotics applications

Piezoelectricity, which translates to “pressure electricity”, is the phenomenon in which certain materials convert mechanical energy to electrical energy, and vice versa. Such materials are common-place and are used in a variety of applications including sensor, actuator, and energy harvesting technologies. The capabilities of such piezoelectric materials have not yet been fully realised. We plan to use computational structural optimisation to design new piezoelectric materials and components that may contribute to novel sensing technologies for robotics applications. Essentially, robots need …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Science
School
School of Mathematical Sciences

Optimising bone shape with memory networks

Bone is a dynamic tissue that optimises its shape to the mechanical loads that it carries. Bone mass is accrued where loads are high, and reduced where loads are low. This adaptation of bone tissue to mechanical loads is well-known and observed in many instances. However, what serves as a reference mechanical state in this shape optimisation remains largely unknown.

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Science
School
School of Mathematical Sciences
Research centre(s)
Centre for Biomedical Technologies

Image-based computational model to predict intracranial aneurysm rupture

Intracranial aneurysms are bulging, weak areas of an artery that supply blood to the brain which are relatively common. While most aneurysms do not show symptoms, 1% spontaneously rupture which can be fatal or it can leave the survivor with permanent disabilities. This catastrophic outcome has motivated surgeons to operate on approximately 30% of aneurysms despite their rate of complications arising and cost of operation.The impact of aneurysm morphology on blood flow shear stress and rupture could educate surgical decision-making …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Engineering
School
School of Mechanical, Medical and Process Engineering
Research centre(s)
Centre for Biomedical Technologies

Developing models of failure for porous materials

Classical fracture mechanics accurately predicts the failure strength of samples with sharp flaws such as pre-existing cracks. However, to predict the failure of porous materials we need to develop an understanding of how stresses are concentrated around smooth flaws in the material such as rounded pores, and how these stress concentrations contribute to failure.Finite fracture mechanics combines the energy criterion for failure from classical fracture mechanics with a stress criterion from macroscopic failure theory. The coupled criterion has by now …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Science
School
School of Mathematical Sciences

Computational methods for multi-scale structural optimisation

Structural optimisation is a powerful computational methodology for finding high-performing designs for structural components or material architectures. For example, what periodic scaffold would provide the highest possible stiffness for its weight?Solving such a problem computationally requires an understanding of the relevant equations required to model the physical properties of interest, as well as efficient implementation of a range of numerical methods including finite elements, finite differences and optimisation.With recent developments in 3D printing technologies it is now becoming possible to …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Science
School
School of Mathematical Sciences

Green polymer-inorganic composite materials

Composite materials are widely researched and widely used in applications such as aircraft, automobiles, ships, structural components and even the space industry.There is a need to create new composite materials which are environmentally friendly and do not use fossil fuel based products. Moreover, the properties of the composites need to be improved while at the same time minimising the costs involved.Consequently our research group is working on composite materials which not only include inexpensive inorganic fillers from the mining sector …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Engineering
School
School of Mechanical, Medical and Process Engineering

Advanced numerical modelling to study fluid flow and heat transfer of ground-mounted photovoltaic panels for the power generation industry

The increase in global energy demand necessitates further advancement in photovoltaic (PV) systems. Advancements in PVs could potentially play a role to help meet the Paris Agreement of limiting global temperature increase to below 2°C.The performance of ground-mounted PV panels commonly found in solar farms depends on a myriad of factors such as tilt angle, microclimate i.e. wind loads, shading, solar irradiance, and dust deposition. This project aims to develop an advanced numerical model, namely computational fluid dynamics (CFD), backed …

Study level
PhD, Honours
Faculty
Faculty of Engineering
School
School of Mechanical, Medical and Process Engineering

Understanding the immunological mechanisms that regulate increased susceptibility to respiratory syncytial viral infection after stem cell transplantation

Allogeneic stem cell transplantation (alloSCT) is considered the gold standard procedure for the treatment of blood cancers. Globally, over 9000 patients per year undergo this high-risk, life-saving therapy. However, major complications limit the therapeutic potential of this treatment which include graft-versus-host disease (GVHD) and infections due to the severe immunosuppression in these patients. Respiratory syncytial viral (RSV) infection is frequent in these patients, is often fatal and clearly a significant clinical problem. Thus, there is a pressing need for new …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

Investigating DNA repair mechanisms in aging adult stem cells

When we age the DNA repair systems of our cells become down regulated. This results in reduced DNA repair capacity, enhanced rates of mutation load and may lead to the development of chronic aging-associated diseases including osteoporosis, Alzheimer's and cancer(1). So it is no surprise that genome instability and stem cell exhaustion, which also strongly correlates with the accumulation of DNA damage, are considered hallmarks of aging(2).However, we still lack a clear understanding on how the decrease in DNA repair …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

The role of genetics in the development and mechanism of human traits

The Statistical and Genomic Epidemiology Laboratory (SGEL) studies the role of genetics in the development and mechanism of human traits, with particular emphasis on migraine, and the specific goal of identifying genetic risk factors and detecting common genetic links with other disorders, in particular depression, endometriosis, and epilepsy.

Study level
PhD, Master of Philosophy
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)
Centre for Genomics and Personalised Health

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