QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.

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Found 127 matching student topics

Displaying 97–108 of 127 results

Reversing Epithelial Mesenchymal Plasticity with Eribulin to Enhance Therapy Response

Epithelial mesenchymal plasticity (EMP) is a highly regulated and powerful cellular process that is fundamental in embryonic development (1), which is hijacked by cancer cells for metastatic progression and therapy resistance in epithelial cancers (2). Eribulin is a microtubule-inhibiting cancer drug discovered in sea sponges and approved for 3rd line therapy in metastatic breast cancer, which was shown to reverse epithelial mesenchymal transition (EMT) (3).We hypothesise that eribulin’s reversal of EMT will sensitise breast cancer cells to other therapies and …

Study level
Master of Philosophy
Faculty
Faculty of Health
School
School of Biomedical Sciences

Assessing visual acuity errors in pre-school children (CVER01)

Measuring visual acuity is in preschool children is challenging. In particular, young children will be prone to making mistakes in identifying symbols on eye charts, even when they can see what those symbols are, so called “false negative responses”.This project uses an established vision assessment protocol, EVA testing, and assesses the extent of false negative responses in this task. The protocol assesses the effects of an intervention, pointing to the target on a card, which may decrease false negative responses. …

Study level
PhD
Faculty
Faculty of Health
School
School of Clinical Sciences
Research centre(s)

Centre for Vision and Eye Research

The benefits of custom fit compression garments on markers of performance and recovery

Cape Bionics has its foundations in the aerospace industry in the design of compression suits worn by astronauts on the international space station. The research which underpinned the design of these space suits has now been applied to sport as a means of improving performance and recovery in elite athletes.For compression garments to be effective they must fit perfectly and apply specific pressure regimes. Cape Bionics use technology from the medical and aerospace industry to provide custom fit compression garments …

Study level
PhD
Faculty
Faculty of Health
School
School of Biomedical Sciences

Antibiotic-loaded polymer nanoparticulate inhaled formulations against lung infections associated with COPD and CF

Lower respiratory tract infections (LRTIs) are one of the fatal diseases of the lungs that have severe impacts on public health especially the Indigenous people. The currently available antibiotics administered orally for the treatment of LRTIs need high doses with frequent administration and cause dose-related adverse effects.To overcome this problem, we will investigate the development of antibiotic-loaded polymer nanoparticles (NPs) for potential pulmonary delivery from dry powder inhaler (DPI) formulations. This study will address the release profile of the antibiotic …

Study level
PhD
Faculty
Faculty of Health
School
School of Clinical Sciences
Research centre(s)
Centre for Materials Science
Centre for Immunology and Infection Control

A Human-centric eXplainable Automated Vehicle

CARRS-Q has developed a strong expertise in AV and ADAS, and operate an Automated Vehicle for its research on test track and open roads.We have collected more than 12,000km of sensor data in various Australian conditions, and we are progressing quickly to a broader understanding of safe operation of AV technologies on our roads. We are looking for PhD candidates to progress further on these topics. PhD positions are available for highly motivated domestic and/or international students to work on …

Study level
PhD
Faculty
Faculty of Health
School
School of Psychology and Counselling

Developing a precision oncology workflow for Osteosarcoma treatment

Osteosarcoma (OS) is the most common malignant bone tumour that primarily affects children and adolescents. With approximately 400 diagnosed cases/year in Australia, OS has the lowest survival rate of all solid cancers and is the leading cause of cancer-related death in Queensland adolescents. Unfortunately, 3 in 4 patients will not survive longer than five years following diagnosis with metastatic OS. Clinical “one size fits all” treatment strategies results in highly variable and unacceptably poor patient responses. Shockingly, both the OS …

Study level
PhD, Master of Philosophy
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)
Centre for Biomedical Technologies

Engineering bioartificial extracellular tumour microenvironments for Osteosarcoma personalised precision oncology

Osteosarcoma (OS) is the most common malignant bone tumour affecting children and adolescents. Importantly, clinical outcomes have not improved for decades, and bone tumours remain to be a leading cause of cancer-related death in adolescents.By identifying ideal treatment approaches for each individual patient, precision oncology has the potential to significantly improve these outcomes. Yet, its widespread application is hindered by a lack of biomaterials that support the reproducible and robust generation of patient-derived osteosarcoma organoids in vitro.Therefore, this project will …

Study level
PhD, Master of Philosophy
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)
Centre for Biomedical Technologies

Wound care in regional/rural Queensland

Barriers to health care for regional/rural residents often relate to the limited availability of local health services and resources and the distance needed to seek suitable specialised services. Wounds experienced in rural and regional areas are often dependent upon the types of employment available, recreational pursuits and risk-taking behaviours.The prevalence of non-communicable lifestyle related risk factors (such as obesity and poor nutrition) and the propensity for an ageing population in rural and regional areas, positions this population group as one …

Study level
PhD, Master of Philosophy
Faculty
Faculty of Health
School
School of Nursing

Understanding how self-image and compassionate goals affect well-being in a social media context

There is increasing concern about the negative impact of social media use on well-being. To understand its impact, we need to move beyond simple conceptualisations of social media use and utilise strong research methods to understand the role that psychological processes play in producing positive and negative impacts. There is preliminary evidence that interpersonal goals play an important role in predicting how people use and experience social media. Self-image goals involve trying to convey a desirable image of oneself to …

Study level
PhD
Faculty
Faculty of Health
School
School of Psychology and Counselling

The Emotional Face

Faces are a rich source of social information communicating social categories like sex, age or ethnicity of a person, but also a person’s emotional state via facial expressions of emotion. The current research investigates how cues available on a face (social category cues, attractiveness, trustworthiness) or what we know about a person affect the manner in which we process emotional expressions.

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Psychology and Counselling

Human Emotional Learning: Likes, Dislikes and Fear

There is currently broad agreement that likes and dislikes, including strong emotional responses such as fear and anxiety, are learned. However, little is known about the manner in which different forms of emotional learning interact or about how emotional learning once acquired can be modified, reduced or eliminated. In particular in the context of fear learning this is problematic as fear memories once acquired seem difficult to change and likely to return even after successful extinction – a phenomenon known …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Psychology and Counselling

Understanding capsular polysaccharide diversity is key to next generation therapies for multi-drug resistant Acinetobacter baumannii infections

Bacteriophage therapy is an attractive innovative treatment for infections caused by extensively drug resistant Acinetobacter baumannii, for which there are few effective antibiotic treatments remaining.Capsular polysaccharide (CPS) is a primary receptor for lytic bacteriophage, thus knowledge of the chemical structures of CPS produced by the species underpins the identification of suitable phage for therapeutic cocktails.As many phage depolymerases cleave a specific CPS linkage formed by either a glycosyltransferase or polymerase enzyme, characterisation of these proteins are essential.However, these remain largely …

Study level
PhD
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)

Centre for Immunology and Infection Control

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