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Found 2 matching student topics

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Early innate immune signatures as biomarkers of Parkinson's disease onset

Parkinson's disease is typically diagnosed after the onset of motor symptoms, when significant neurodegeneration has already occurred. Growing evidence suggests that immune dysregulation, particularly within the innate immune system, may arise in the prodromal and early stages of disease and contribute to disease initiation.This project will investigate whether individuals in the prodromal and early stages of Parkinson's disease exhibit distinct peripheral immune signatures, focusing on monocyte and macrophage polarisation and plasma cytokine profiles, with the aim of identifying early immune …

Study level
Master of Philosophy
Faculty
Faculty of Health
School
School of Biomedical Sciences

Using mathematics to understand multiple sclerosis: what causes the immune system to attack the brain?

Every day, we use our bodies to move, think, talk and eat, but for people with multiple sclerosis (MS) these tasks can be virtually impossible. MS is a chronic disease which develops because the immune system has started to attack the nerve cells in the brain. This causes the degradation of parts of the brain and irreversible impairment in physical and mental activity. Unfortunately, this disease has no cure, and while considerable therapeutic advances against this disease have been achieved, …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Science
School
School of Mathematical Sciences

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