QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 90 matching student topics
Displaying 13–24 of 90 results
Unravelling the function of PSA variants in prostate cancer
OverviewProstate cancer (PCa) is the second-most common cancer in men. Prostate-specific antigen (PSA) encoded by the KLK3 gene is the only FDA-approved PCa biomarker for PCa. As a serine protease, PSA can also regulate multiple functions involved in PCa progression and metastasis and is summarised in our recent publications. Immunotherapies, including PSA-targeting therapies, have shown modest improvement in survival, for only a subset of metastatic PCa patients. Not much is known on the immunoregulatory role of PSA or its variants, …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Genomics and Personalised Health
The role of genetics in the development and mechanism of human traits
The Statistical and Genomic Epidemiology Laboratory (SGEL) studies the role of genetics in the development and mechanism of human traits, with particular emphasis on migraine, and the specific goal of identifying genetic risk factors and detecting common genetic links with other disorders, in particular depression, endometriosis, and epilepsy.
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Genomics and Personalised Health
Identifying novel pheno-endotypes in children with chronic cough
Chronic wet cough is among the commonest symptoms of chronic lung disease. In Australia, the most common cause of childhood chronic wet cough is protracted bacterial bronchitis (PBB), a clinical entity we first described. It has now been shown to be a precursor to bronchiectasis, which causes substantial morbidity and mortality, especially from acute respiratory exacerbations. Lung inflammation in children with persistent chronic wet cough is an important driver of ongoing and progressive tissue damage, leading to bronchiectasis, highlighting the …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Public Health and Social Work
- Research centre(s)
- Centre for Healthcare Transformation
Australian Centre for Health Services Innovation
Unleashing the full potential of terminators for the regulation of gene expression in plants
Ultimately, the proper development of a plant and its ability to adapt to its environment is the result of how plants’ genes are expressed and interact with each other. Hence, it is of extreme importance to understand the mechanisms used by plants to regulate gene expression.Modification of the expression pattern of a gene is particularly important in modern biology. By changing the expression levels of a gene, it is possible to learn about its function, increase the production of a …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Science
- School
- School of Biology and Environmental Science
- Research centre(s)
- Centre for Agriculture and the Bioeconomy
Genetics of cardiovascular disease
This research project involves investigating the genetic basis of cardiovascular disease (CVD). The project will focus on the genetically unique population of Norfolk Island. The Norfolk Island Health Study has been running for 20 yrs. Over this time the cardiovascular health of the Islanders has been tracked via the collection of relevant clinical data. In addition whole genome sequence data from the study group has been collected, which will facilitate the discovery of genetic variants that influence CVD phenotypes - …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Genomics and Personalised Health
Overcoming the challenges of sensitive data via synthetic data generation (case study)
In the 21st Century, there is an abundance of data, often containing insights that could benefit a number of stakeholders. However, despite this opportunity, it is often the case that the data is sensitive and can not be released by organisations or government agencies due to privacy concerns. One possible solution to the above dilemma is to instead carefully construct a 'twin' data set that contains similar information (and ideally, the same insights) as the original data set, but without …
- Study level
- Honours
- Faculty
- Faculty of Science
- School
- School of Mathematical Sciences
- Research centre(s)
- Centre for Data Science
Scalable software solutions for improving the CRISPR gene editing system
The CRISPR-Cas9 technology allows the modification of virtually any gene in any organism of interest. It has generated a lot of interest, both in the research community and the general population.One of the crucial components of CRISPR experiments is the design of the 'guide RNAs' that will control where modifications occur. We have developed a software pipeline, named Crackling, to identify safe and effective guide RNAs across entire genomes.We are seeking to expand and improve various aspects of our current …
- Study level
- Honours
- Faculty
- Faculty of Science
- School
- School of Computer Science
- Research centre(s)
- Centre for Data Science
Visualisation of CRISPR targets
CRISPR-Cas9 technology allows us to modify virtually any gene in any organism of interest. It has generated a lot of interest, both in the research community and the general population.One of the crucial components of CRISPR experiments is the design of the 'guide RNAs' that will control where modifications occur.We have developed a software pipeline, named Crackling, to identify safe and effective guide RNAs across entire genomes. We're now seeking to develop a visualisation to communicate the results produced by …
- Study level
- Honours
- Faculty
- Faculty of Science
- School
- School of Computer Science
- Research centre(s)
- Centre for Data Science
Leading diversity
Diversity is a buzz word in many organizations today. While having a diverse team promise potential for innovation and creativity, it can also create many challenges. Leading diversity will be an important capability for future leaders.
- Study level
- PhD
- Faculty
- Faculty of Business and Law
- School
- School of Management
- Research centre(s)
- Centre for Future Enterprise
Australian Centre for Entrepreneurship Research
Immigrant entrepreneurship
Immigrants start their own business either out of necessity or opportunity. They engage in all different types of business activities, ranging form the small business inside the ethnic enclaves to the multinational enterprises across the globe.We are interested in new insights you can bring from your own research, business or community background. Please pitch your idea to us for the opportunity to create new knowledge together.
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Business and Law
- School
- School of Management
- Research centre(s)
- Centre for Future Enterprise
Australian Centre for Entrepreneurship Research
Enhancing wellbeing of youth from culturally diverse and refugee backgrounds
Australia has a multicultural population, with approximately 30% of the population from diverse backgrounds. We will propose a program of research encompassing the development of assessment processes and also interventions, addressing the diverse needs of this population, Proposed research will build upon work already undertaken by the team in collaboration with Education Queensland including Milpera State School. Methodologies to date have been broadly based, including both quantitative and qualitative approaches. These have included the examination of psychometric properties of scales …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Psychology and Counselling
- Research centre(s)
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Australian Centre for Philanthropy and Nonprofit Studies
Advanced artificial intelligence based ultrasound imaging applications
Our research in the space of advanced quantitative medical imaging is investigating how to use ultrasound as a real time volumetric mapping tool of human tissues, to guide in a reliable and accurate way complex medical procedures1. We have developed several novel methods which make use of the most cutting-edge artificial intelligence technology2. For example, to show where the treatment target and the organs at risk are at all times during treatments in radiation therapy3, 4; or to inform robots …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Clinical Sciences
- Research centre(s)
- Centre for Biomedical Technologies
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