QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 2 matching student topics
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Early innate immune signatures as biomarkers of Parkinson's disease onset
Parkinson's disease is typically diagnosed after the onset of motor symptoms, when significant neurodegeneration has already occurred. Growing evidence suggests that immune dysregulation, particularly within the innate immune system, may arise in the prodromal and early stages of disease and contribute to disease initiation.This project will investigate whether individuals in the prodromal and early stages of Parkinson's disease exhibit distinct peripheral immune signatures, focusing on monocyte and macrophage polarisation and plasma cytokine profiles, with the aim of identifying early immune …
- Study level
- Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Why do epithelial cells have antigen processing machinery?
Epithelial Cells (ECs) constitute the border between the host immune system and an environment teeming with inhaled antigens. Work from us and others has highlighted that ECs have the ability to express the antigen processing and presentation machinery, Major Histocompatibility Complex class II (MHC II) that is important in initiating immune responses. MHC II expression and function on mucosal epithelial cells, is not well understood.Whilst MHC II is expressed by ECs, and is altered with inflammation, there is a paucity …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
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