QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 2 matching student topics
Displaying 1–2 of 2 results
Modelling the osteoid: A quantitative experimental–mathematical platform for osteocyte network formation and transport
Project Reference: #4MPQC-NATP3Preferred Project Start: Late 2026/Early 2027How does a newly formed bone matrix develop into a mineralised tissue containing a functional osteocyte network, and how does this transformation affect the movement of nutrients and signals?During bone formation, osteoblasts produce a soft, initially unmineralised extracellular matrix known as osteoid. Some osteoblasts gradually become embedded within this matrix and transition into osteocytes, extending dendritic processes that connect them into an intricate three-dimensional network. As the osteoid matures and mineralises, its architecture, …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Biomedical Technologies
Understanding cellular-spatial interplay between osteocyte networks and their environment using bioengineered 3D bone models
Project Reference: #1MPQC-NATP1Preferred Project Start: ImmediateHow do bone-forming cells communicate to build and maintain a functional bone matrix?Osteoblasts produce new bone extracellular matrix, while osteocytes become embedded within this matrix and form an interconnected network that helps regulate bone formation, adaptation and remodelling. Although these cells work closely together in the body, their interactions are difficult to reproduce and investigate using conventional two-dimensional cell culture.Bone-cell behaviour is strongly influenced by the surrounding microenvironment, including its composition, mechanical properties, mineral content, …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
- Research centre(s)
- Centre for Biomedical Technologies
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