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α-Synuclein–specific T-cell responses as early adaptive immune markers of Parkinson's disease
Parkinson’s disease develops over many years before motor symptoms become clinically apparent, limiting opportunities for early intervention. Increasing evidence suggests that adaptive immune responses, particularly T cells that recognise α-synuclein, may emerge during at-risk and early stages of disease.This project will investigate whether α-synuclein–specific T cells are expanded in at-risk individuals and early Parkinson's disease patients, with the goal of identifying early immune changes that may precede clinical disease onset.
- Study level
- Master of Philosophy
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
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