QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 281 matching student topics
Displaying 61–72 of 281 results
Characterisation of melanoma cell membranes to identify novel drug targets
Cell membrane structure and function are altered during tumour development, but to date comprehensive studies on the characterisation of cell membranes of a given cancer are scarce, or are only focused on a particular property (e.g. overall charge, global lipid composition, or specific lipid). In preliminary work we compared the lipidome (i.e. the lipid profile) of a panel of cells, and found the lipid composition of model melanoma cells to be distinct from that of other cancerous and non-cancerous cells. …
- Study level
- PhD
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Characterise a novel DNA repair protein as a target for cancer therapies
Data generated in the lab has identified a novel DNA repair protein previously described as a key protein in HSP70/90 complexes. Many pathways of tumourigenesis are mediated by Heat Shock Proteins and HSP70/90 are found significantly upregulated in ovarian cancers. The targeting of HSP70/90 are an emerging therapeutic avenue for the treatment of ovarian cancer. Supporting this, an inhibitor of HSP90 has been shown to sensitise breast cancer cells to PARP inhibitors and paclitaxel.Our preliminary data indicates that this new …
- Study level
- Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Characterising the role of PARPs in DNA repair and cancer therapy
The genome of our cells is damaged multiple times each day, by various factors including sunlight and reactive oxygen species. In order for the DNA damage response to be efficient, our cells utilise highly coordinated repair pathways that function accurately and rapidly throughout the damaged cell. Cells that do not repair DNA damage correctly will accumulate damage and display increased genomic instability, which is a key hallmark of cancer cells, promoting their survival and rapid growth. DNA repair pathways are …
- Study level
- Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Robotic intention visualisation
Complex manufacturing environments characterised by high value and high product mix manufacturing processes pose challenges to Human-Robot Collaboration (HRC). Allowing people to see what robots are ‘thinking’ will allow workers to efficiently collaborate with co-located robotic partners. A tighter integration of work routines requires improved approaches to support awareness in human-robotic co-working spaces. There is a need for solutions that also let people see what the robot is intending to do so that they can also efficiently adjust their actions …
- Study level
- PhD
- Faculty
- Faculty of Creative Industries, Education and Social Justice
- School
- School of Design
- Research centre(s)
-
Design Lab
Elevating performance: Innovative design strategies for body-worn (diagnostic or biosensing) devices
How does technology help us to support a person’s sense of wellbeing and/or performance? Beyond technology and metrics, how do a body-worn (electronic/biosensing) device be designed to fit the person in different contexts of use and different performance needs? We are investigating the role of designing with sensor technology (sensor technology agnostic) in body-worn devices from a Human Centred (HCD) lens, and Research through Design (RtD) approach.In today's fast-paced world, the pursuit of optimal human performance has become a paramount …
- Study level
- PhD
- Faculty
- Faculty of Creative Industries, Education and Social Justice
- School
- School of Design
- Research centre(s)
-
Design Lab
My flow: Menstrual cycle Femtech for elite athlete performance optimisation through wearable technology
There is a need for additional studies to monitor on-field performance parameters in female elite athletes (Meignié 2021). We know that wearable sensors can be used to monitor the physiological and biochemical profile of athletes (Seshadri 2019), and a combination of several wearables is going to be more effective for accessing all relevant parameters (Düking 2016). However, there is limited research on the effects of menstrual cycle phases on elite athlete performance (Meignié 2021).This proposed research aims to bridge the …
- Study level
- PhD
- Faculty
- Faculty of Creative Industries, Education and Social Justice
- School
- School of Design
- Research centre(s)
-
Design Lab
Medication and dietary supplement use and symptom severity of chemotherapy-induced peripheral neuropathy
Chemotherapy-induced peripheral neuropathy (CIPN) is highly prevalent and clinically problematic, occurring in up to 60–80% of people receiving chemotherapy. Despite the high prevalence and significant patient and healthcare burden of CIPN, treatment options are limited.This project will explore the association between medication and dietary supplement use and symptom severity of CIPN to identify factors that might worsen or improve CIPN symptoms.
- Study level
- Honours
- Faculty
- Faculty of Health
- School
- School of Nursing
- Research centre(s)
- Centre for Healthcare Transformation
Cancer and Palliative Care Outcomes Centre
Human biomarkers of stress, trauma, and memories of fear
Understanding how disorders such as posttraumatic stress disorder develop following trauma is a contemporary challenge for researchers in psychology. The best explanations involve a combination of psychological and biological factors that interact during and following trauma to create a range of troubling symptoms. This project will use cutting edge technology at QUT to provide insights into how a mix of biology and behaviour can result in exacerbated stress responses and threat memories in experimental and real-world settings.
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Psychology and Counselling
Designing smart cities for more-than-human futures
Cities are changing across the globe. Climate change, rapid urbanisation, pandemics, as well as innovations in technologies such as blockchain, AI and IoT are all impacting urban space. One response to such changes has been to make cities ecologically sustainable and 'smart'. The 'eco smart city', for instance, uses networked sensing, cloud and mobile computing to optimise, control, and regulate urban processes and resources. From real-time bus information, autonomous electric vehicles, smart parking, and smart street lighting, such initiatives are …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Creative Industries, Education and Social Justice
- School
- School of Design
- Research centre(s)
-
Design Lab
Board interlocks and firm decisions
Board interlocks research is one of the most vibrant areas in corporate governance research. A board interlock is a tie created by two firms sharing a common director. In other words, a director can hold multiple directorships in more than one firm. Board interlocks reflect complex inter-organisational relationships which play an important role in determining a firm’s strategies and structures.Prior research finds that board interlocks have an impact on reducing environmental uncertainty, gaining access to diverse and unique information, diffusing …
- Study level
- PhD, Master of Philosophy
- Faculty
- Faculty of Business and Law
- School
- School of Accountancy
Human Emotional Learning: Likes, Dislikes and Fear
There is currently broad agreement that likes and dislikes, including strong emotional responses such as fear and anxiety, are learned. However, little is known about the manner in which different forms of emotional learning interact or about how emotional learning once acquired can be modified, reduced or eliminated. In particular in the context of fear learning this is problematic as fear memories once acquired seem difficult to change and likely to return even after successful extinction – a phenomenon known …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Psychology and Counselling
NHMRC Idea Grant: intergenerational living and learning models
This research project acts upon recommendations from the Inquiry into the Quality of Care and Residential Aged Care in Australia IQCRAC (2018) by developing an inter-generational model for senior living within school campuses in consultation with industry partners. The project differs from existing programs by establishing an economic policy-driven 'shared campus facilities and services' approach which is person-centred, health focused and socially inclusive. The model intends to be translatable across diverse Australian contexts, from urban realms where land is limited, …
- Study level
- PhD, Master of Philosophy, Honours
- Faculty
- Faculty of Creative Industries, Education and Social Justice
- School
- School of Design
- Research centre(s)
-
Design Lab
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