The extracellular matrix (ECM) secreted by cells is composed of a meshwork of fibres infiltrated with proteins and/or minerals. This fibre meshwork often matures after its creation by rearranging its structure. In this project, the fibre meshwork will be represented by a continuous anisotropic field.
You will derive evolution equations to describe the fibre creation taking place at moving cell membranes and the subsequent maturation of the meshwork.
Applications include the investigation of:
- twisted fiber arrangements in tissues grown in bioscaffold constructs
- the generation of an anistropic network of interconnected cells in bones
- anisotropic molecular transport in the meshwork.
You may be able to apply for a research scholarship in our annual scholarship round.
Contact the supervisor for more information.