Dr Sri Srinivasan
This person does not currently hold a position at QUT.
Dr Sri Srinivasan has more than 11 years of research experience in prostate cancer genetics and molecular biology. She completed her Master degrees in Microbial Gene Technology and Biotechnology in India in 2007. In 2017, she completed her PhD in prostate cancer genetics and molecular biology at Queensland University of Technology (QUT) . Her research focuses on understanding the biological impact of prostate cancer risk associated germline variants in prostate cancer predisposition and development; and identifying novel biomarkers for accurate diagnosis and prognosis specifically for metastatic PCa which is associated with severe morbidity and disease outcomes. Dr Srinivasan received an Advanced Queensland Research Fellowship in 2017 to pursue her research as an Early Career Researcher at QUT in partnership with Queensland Health (Pathology) and the Translation Research Institute, Brisbane. In 2018, she received the John Mills Prostate Cancer Foundation of Australia’s Young Investigator Award to navigate the successful translation of novel prostate cancer diagnostics. In 2017, she was a national finalist of the Women In Technology (WiT) Life Sciences Young Achiever Award. She has received many other awards, noteworthy is her E.K. Frey-Werle Foundation Award in 2019, multiple travel grants and opportunities to present her research at International conferences. Dr Sri Srinivasan has also co-authored publications in high impact factor journals such as Nature Genetics, Cancer Discovery, Nature Communications and Clinical Chemistry among others.
Genetics, Oncology and Carcinogenesis, Biochemistry and Cell Biology
Field of Research code, Australian and New Zealand Standard Research Classification (ANZSRC), 2008
- Doctor of Philosophy (Queensland University of Technology)
Professional memberships and associations
• Member of Woman in Technology
• Member of Metastasis Research Society (MRS)
• Member of Australian Society for Metastasis Research (OzMRS)
• Member of the Australian Society for Biochemistry and Molecular Biology
• Member of the Australia and New Zealand Society for Cell and Developmental Biology
- Janaththani P, Munasinghage Silva L, Srinivasan S, Snell C, Williams E, Fazli L, Gleave M, Batra J, Nelson C, Tate E, Harris J, Hooper J, Clements J, Bock N, Lovell S, Rockstroh A, Lehman M, Lesner A, Kryza T, (2020) The molecular function of kallikrein-related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer, Molecular Oncology, 14 (1), pp. 105-128.
- Matin F, Jeet V, Srinivasan S, Cristino A, Janaththani P, Clements J, Batra J, (2019) MicroRNA-3162-5p-mediated crosstalk between kallikrein family members including prostate-specific antigen in prostate cancer, Clinical Chemistry, 65 (6), pp. 771-780.
- Srinivasan S, Stephens C, Wilson E, Janaththani P, DeVoss K, Koistinen H, Stenman U, Brook M, Buckle A, Klein R, Lilja H, Clements J, Batra J, (2019) Prostate cancer risk-associated single-nucleotide polymorphism affects prostate-specific antigen glycosylation and its function, Clinical Chemistry, 65 (1).
- Moya L, Lai J, Hoffman A, Srinivasan S, Janaththani P, Chambers S, Clements J, Batra J, (2018) Association analysis of a microsatellite repeat in the TRIB1 gene with prostate cancer risk, aggressiveness and survival, Frontiers in Genetics, 9, pp. 1-12.
- Lai J, Moya L, An J, Hoffman A, Srinivasan S, Janaththani P, Walpole C, Perry-Keene J, Chambers S, Lehman M, Nelson C, Clements J, Batra J, other a, (2017) A microsatellite repeat in PCA3 long non-coding RNA is associated with prostate cancer risk and aggressiveness, Scientific Reports, 7, pp. 1-14.
- Srinivasan S, Clements J, Batra J, (2016) Single nucleotide polymorphisms in clinics: Fantasy or reality for cancer?, Critical Reviews in Clinical Laboratory Sciences, 53 (1), pp. 29-39.
- Stegeman S, Amankwah E, Klein K, O'Mara T, Kim D, Lin H, Permuth Wey J, Sellers T, Srinivasan S, Eeles R, Clements J, Batra J, other a, (2015) A large-scale analysis of genetic variants within putative miRNA binding sites in prostate cancer, Cancer Discovery, 5 (4), pp. 368-379.
- Eeles R, Olama A, Benlloch S, Saunders E, Leongamornlert D, Tymrakiewicz M, Ghoussaini M, Luccarini C, Dennis J, Jugurnauth-Little S, Batra J, Clements J, Srinivasan S, other a, (2013) Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array, Nature Genetics, 45 (4), pp. 385-391.
- Lose F, Lawrence M, Srinivasan S, O'Mara T, Marquart L, Chambers S, Gardiner R, Aitken J, Spurdle A, Batra J, Clements J, (2012) The kallikrein 14 gene is down-regulated by androgen receptor signalling and harbours genetic variation that is associated with prostate tumour aggressiveness, Biological Chemistry, 393 (5), pp. 403-412.
- Batra J, Lose F, O'Mara T, Marquart L, Stephens C, Alexander K, Srinivasan S, Eeles R, Easton D, Olama A, Kote-Jarai Z, Guy M, Muir K, Lophatananon A, Rahman A, Neal D, Hamdy F, Donovan J, Chambers S, Gardiner R, Aitken J, Yaxley J, Kedda M, Clements J, Spurdle A, (2011) Association between prostinogen (KLK15) genetic variants and prostate cancer risk and aggressiveness in Australia and a meta-analysis of GWAS data, PLoS One, 6 (11), pp. 1-8.
- Deciphering the biological impact of prostate cancer risk associated PSA coding variant
- Primary fund type
- CAT 1 - Australian Competitive Grant
- Project ID
- Start year
- Single nucleotide polymorphisms; Mutation; Glycosylation; Prostate-specific antigen; Prognosis