Dr Akhilandeshwari Ravichandran
Faculty of Engineering,
School of Mech., Medical & Process Engineering
Biography
Dr Akhilandeshwari (Akhila) Ravichandran is a Lecturer in the School of Mechanical, Medical, and Process Engineering, Queensland University of Technology (QUT), Australia. Akhila graduated her Bachelors in Bioengineering from India, followed by a PhD in Biomedical Engineering from Nanyang Technological University, Singapore. Her doctoral research focussed on the development and evaluation of mechanical bioreactors for generation of bone tissues from 3D printed, polymer-composite scaffolds and stem cells. The research was done in collaboration with a biomedical company and led to the filing of an international PCT patent application (2021). Akhila continued her biomedical research pursuits in the Centre in Regenerative Medicine group at QUT, Australia from 2018 to 2020. Here, she worked closely with Dr. Nathalie Bock and DProf. Dietmar Hutmacher and conducted interdisciplinary research in the fields of tissue engineering, biomaterials, mechanics, and large animal histology. Since 2021, she has been working as a Postdoctoral Research Fellow with A/Prof Laura Bray on 3D tissue microenvironment models. Akhila is passionate about engaging with students and has been actively involved in mentoring high school students from Queensland Academies for their research projects. Her current research interests include microvascular engineering, 3D radiobiology models, and breast cancer spatial transcriptomics.
Personal details
Positions
- Lecturer
Faculty of Engineering,
School of Mech., Medical & Process Engineering
Keywords
Tissue engineering, Cancer models, Regenerative medicine, Breast cancer, Radiobiology, Bioengineering
Research field
Biomedical engineering, Biochemistry and cell biology, Medical biotechnology
Field of Research code, Australian and New Zealand Standard Research Classification (ANZSRC), 2020
Qualifications
- Doctor of Philosophy (Nanyang Technological University)
Publications
- Koch, M., Ravichandran, A., Murekatete, B., Clegg, J., Joseph, M., Hampson, M., Jenkinson, M., Bauer, H., Snell, C., Liu, C., Gough, M., Thompson, E., Werner, C., Hutmacher, D., Haupt, L. & Bray, L. (2023). Exploring the Potential of PEG-Heparin Hydrogels to Support Long-Term Ex Vivo Culture of Patient-Derived Breast Explant Tissues. Advanced Healthcare Materials, 12(14), Article 2202202. https://eprints.qut.edu.au/237289
- Clegg, J., Koch, M., Ravichandran, A., Hutmacher, D. & Bray, L. (2022). Engineering mammary tissue microenvironments in vitro. In S. Nilsson (Ed.), Recapitulating The Stem Cell Niche Ex Vivo (pp. 145–178). Academic Press. https://eprints.qut.edu.au/230382
- Ravichandran, A., Clegg, J., Adams, M., Hampson, M., Fielding, A. & Bray, L. (2021). 3D breast tumor models for radiobiology applications. Cancers, 13(22), Article 5714. https://eprints.qut.edu.au/227508
- Ravichandran, A., Meinert, C., Bas, O., Hutmacher, D. & Bock, N. (2021). Engineering a 3D bone marrow adipose composite tissue loading model suitable for studying mechanobiological questions. Materials Science and Engineering C, 128, Article 112313. https://eprints.qut.edu.au/213765
- Ravichandran, A., Murekatete, B., Moedder, D., Meinert, C. & Bray, L. (2021). Photocrosslinkable liver extracellular matrix hydrogels for the generation of 3D liver microenvironment models. Scientific Reports, 11, Article 15566. https://eprints.qut.edu.au/229291
- Koch, M., Jaeschke, A., Murekatete, B., Ravichandran, A., Tsurkan, M., Werner, C., Soon, P., Hutmacher, D., Haupt, L. & Bray, L. (2020). Stromal fibroblasts regulate microvascular-like network architecture in a bioengineered breast tumour angiogenesis model. Acta Biomaterialia, 114, 256–269. https://eprints.qut.edu.au/203136
- Ravichandran, A., Wen, F., Lim, J., Chong, M., Chan, J. & Teoh, S. (2018). Biomimetic fetal rotation bioreactor for engineering bone tissues-Effect of cyclic strains on upregulation of osteogenic gene expression. Journal of Tissue Engineering and Regenerative Medicine, 12(4). https://eprints.qut.edu.au/233009
- Ravichandran, A., Liu, Y. & Teoh, S. (2018). Review: bioreactor design towards generation of relevant engineered tissues: focus on clinical translation. Journal of Tissue Engineering and Regenerative Medicine, 12(1). https://eprints.qut.edu.au/233011
QUT ePrints
For more publications by Akhilandeshwari, explore their research in QUT ePrints (our digital repository).
Filter publications:
A complete list of publications is available at: https://www.qut.edu.au/about/our-people/academic-profiles/akhilandeshwari.ravichandran
Supervision
Current supervisions
- Dissecting Hypofractionated Radiation Therapy Responses of Patient-derived Explant Cultures of Breast and Prostate Cancer
PhD, Principal Supervisor
Other supervisors: Professor Laura Bray, Dr Hoang Son Pham - Dissecting tissue-specific endothelial cell dynamics using bioengineered matrices
PhD, Associate Supervisor
Other supervisors: Professor Laura Bray, Professor Yi-Chin Toh - Exploring drug resistance in a bioengineered model of acute myeloid leukaemia
PhD, Associate Supervisor
Other supervisors: Professor Laura Bray - Reconstructing and defining the ECM microenvironments of organ-specific microvasculature using bioengineered systems
PhD, Associate Supervisor
Other supervisors: Professor Laura Bray, Dr Arutha Kulasinghe - Tissue-specific extracellular matrices for patient-derived osteosarcoma organoid culture and personalised medicine
PhD, Associate Supervisor
Other supervisors: Dr Christoph Meinert, Dr Jacqui Mcgovern
Completed supervisions (Masters by Research)
The supervisions listed above are only a selection.