Associate Professor
Yi-Chin Toh

Faculty of Engineering,
School of Mech., Medical & Process Engineering
Biography
Yi-Chin Toh is a Future Fellow and Associate Professor at the Queensland University of Technology. She obtained her B.Eng in Chemical Engineering and Ph.D in Bioengineering from the National University of Singapore in 2001 and 2008 respectively. She did her post-doctoral training at the Massachusetts Institute of Technology in 2008 under Professor Joel Voldman's guidance. Before joining QUT, she was an Assistant Professor at the Department of Biomedical Engineering, National University of Singapore.Yi-Chin leads the Micro Tissue Engineering Lab (https://microtelab.com/). Her major scientific contribution is in the advancement of microfluidic tissue models for applications in drug testing and experimental biology. To date, she has published over 40 papers in leading scientific journals such as Biomaterials and Lab on a Chip. Her current research interest is in engineering multi-scale tissue models to mimic complex biological interactions during human development and diseases, as well as translating them into scalable platforms for disease modeling and drug testing applications. Her lab is also working on integrating microfluidics and biofabrication technologies to realise a new generation of human-on-chips. Dr Toh is a recipient of the Australia Research Council Future Fellowship, National University of Singapore Research Scholarship, A*STAR Graduate Scholarship and A*STAR International Fellowship.
Personal details
Positions
- Associate Professor
Faculty of Engineering,
School of Mech., Medical & Process Engineering- Kelvin Grove Q Block Membership
Institute of Health Biomedical Innovation (IHBI),
IHBI Science and Engineering Projects - Kelvin Grove Q Block Membership
Discipline
Biomedical Engineering, Interdisciplinary Engineering
Field of Research code, Australian and New Zealand Standard Research Classification (ANZSRC), 2008
Qualifications
- PhD in Bioengineering (National University of Singapore)
Professional memberships and associations
Associate Editor, Biomicrofluidics
Associate Editor, Frontiers in Digital Health (Personalised Medicine)
Editorial board member, Micromachines
Poster judging committee, MicroTAS (Co-chair, 2018 / Chair, 2019)
Executive Technical Program Committee, MicroTAS (2021-)
Selected publications
- Ong L, Ching T, Chong L, Arora S, Li H, Hashimoto M, DasGupta R, Yuen P, Toh Y, (2019) Self-aligning Tetris-Like (TILE) modular microfluidic platform for mimicking multi-organ interactions, Lab on a Chip, 19 (13), pp. 2178-2191.
- Sahni G, Chang S, Meng J, Tan J, Fatien J, Bonnard C, Utami K, Chan P, Tan T, Altunoglu U, Kayserili H, Pouladi M, Reversade B, Toh Y, (2021) A Micropatterned Human-Specific Neuroepithelial Tissue for Modeling Gene and Drug-Induced Neurodevelopmental Defects, Advanced Science, 8 (5).
- Ching T, Vasudevan J, Tan H, Lim C, Fernandez J, Toh Y, Hashimoto M, (2021) Highly-customizable 3D-printed peristaltic pump kit, HardwareX, 10.
- Ching T, Toh Y, Hashimoto M, Zhang Y, (2021) Bridging the academia-to-industry gap: organ-on-a-chip platforms for safety and toxicology assessment, Trends in Pharmacological Sciences, 42 (9), pp. 715-728.
- Ching T, Toh Y, Hashimoto M, (2020) Fabrication of Complex 3D Fluidic Networks via Modularized Stereolithography, Advanced Engineering Materials, 22 (3).
- Arora S, Lam A, Cheung C, Yim E, Toh Y, (2019) Determination of critical shear stress for maturation of human pluripotent stem cell-derived endothelial cells towards an arterial subtype, Biotechnology and Bioengineering, 116 (5), pp. 1164-1175.
- Ching T, Li Y, Karyappa R, Ohno A, Toh Y, Hashimoto M, (2019) Fabrication of integrated microfluidic devices by direct ink writing (DIW) 3D printing, Sensors and Actuators, B: Chemical, 297, pp. 1-9.
- Arora S, Lin S, Cheung C, Yim E, Toh Y, (2020) Topography elicits distinct phenotypes and functions in human primary and stem cell derived endothelial cells, Biomaterials, 234.
- Chong L, Li H, Wetzel I, Cho H, Toh Y, (2018) A liver-immune coculture array for predicting systemic drug-induced skin sensitization, Lab on a Chip, 18 (21), pp. 3239-3250.
- Ong L, Islam A, DasGupta R, Iyer N, Liang L, Toh Y, (2017) A 3D printed microfluidic perfusion device for multicellular spheroid cultures, Biofabrication, 9 (4), pp. 1-12.
QUT ePrints
To find publications by Yi-Chin, visit QUT ePrints, the University's research repository.
Awards
- Type
- Academic Honours, Prestigious Awards or Prizes
- Reference year
- 2020
- Details
- Lab on a Chip Outstanding Reviewer Award
- Type
- Editorial Role for an Academic Journal
- Reference year
- 2020
- Details
- Associate Editor of APL Biomicrofluidics
- Type
- Academic Honours, Prestigious Awards or Prizes
- Reference year
- 2019
- Details
- International Global 3Rs Award International Global 3Rs Award
- Type
- Editorial Role for an Academic Journal
- Reference year
- 2019
- Details
- Associate Editor for Frontiers in Digital Health (Personalised Medicine)
- Type
- Recipient of a Nationally Competitive Research Fellowship
- Reference year
- 2020
- Details
- Australian Research Council (ARC) Discovery Project (DP20) "A Micro-Physiological System to Mimic Human Microbiome-Organ Interactions"
- Type
- Editorial Role for an Academic Journal
- Reference year
- 2017
- Details
- Associate Editor for MDPI Micromachines
Research projects
- Title
- A Micro-Physiological System to Mimic Human Microbiome-Organ Interactions
- Primary fund type
- CAT 1 - Australian Competitive Grant
- Project ID
- DP200101658
- Start year
- 2020
- Keywords
- Title
- ARC ITTC (CTET) for Cell and Tissue Engineering Technologies
- Primary fund type
- CAT 1 - Australian Competitive Grant
- Project ID
- IC190100026
- Start year
- 2019
- Keywords
- Title
- Modular microfluidic platform for mimicking multi-organ system interactions
- Primary fund type
- CAT 1 - Australian Competitive Grant
- Project ID
- FT180100157
- Start year
- 2019
- Keywords
Supervision
Current supervisions
- A 3D Printed Hydrogel Microfluidic Vascular Model for Studying the Interplay between Atherogenic Hemodynamic and Vascular Cells
PhD, Associate Supervisor
Other supervisors: Professor Zhiyong Li, Professor Prasad Yarlagadda - Tissue-specific hydrogels for local niche generation in multi-organ-on-chips
PhD, Principal Supervisor
Other supervisors: Distinguished Professor Dietmar W Hutmacher - Development a bacterial-intestine-immune coculture system in the compartmentalised microfluidic device for inflammatory bowel disease associated bacteria pathogenesis
PhD, Principal Supervisor
Other supervisors: Distinguished Professor Dietmar W Hutmacher, Dr Louis Ong - Design of a Dynamic Flow Model and Study the Antibacterial Effect of Micro/Nanostructured Surfaces under Flow Conditions
PhD, Associate Supervisor
Other supervisors: Professor Prasad Yarlagadda, Dr Asha Mathew - Understanding the Haemodynamics and Vessel Wall Mechanics of Intracranial Aneurysm Progression and Rupture
PhD, Associate Supervisor
Other supervisors: Professor Zhiyong Li, Professor Emilie Sauret - Numerical Modelling and Simulations of Elastic Turbulence Mixing for Microfluidic Applications
PhD, Associate Supervisor
Other supervisors: Professor Emilie Sauret