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Adjunct Professor
Flavia Huygens
Faculty of Health,
School of Biomedical Sciences
Biography
Research theme:Environment, Food, Health
Research discipline:
Cell and Molecular Biosciences
Research areas
Bioinformatics approach to microbial source tracking in environmental water: Application of the "Minimum SNPs" data mining software program as a genetic fingerprinting tool used to track microbial populations in water sources. High-resolution DNA-melt analysis as a genetic fingerprinting tool to classify bacterial populations: Analysis of tandem-repeat DNA sequences and single-nucleotide polymorphisms present in bacterial genomes by high-resolution melt analysis. Molecular characterisation of intestinal micro-organisms associated with Crohn's disease: Real-time quantitative PCR analysis of microbial organisms present in patients diagnosed with Crohn's disease. Microbial Genotyping Sub-Program Cooperative Research Centre for Diagnostics: Application of the software program "Minimum SNPs" to identify sets of highly informative single nucleotide polymorphisms present in comparative genomic databases of bacterial organisms. Genetic fingerprinting of Staphylococcus aureus using highly informative (high D-value) single nucleotide polymorphisms.
Areas of expertise
- Clinical Microbiology
- Molecular Microbiology
- Bioinformatics
- Genomics
- Novel antimicrobial agents
Personal details
Positions
- Adjunct Professor
Faculty of Health,
School of Biomedical Sciences
Keywords
Bacterial genomics, Bacterial virulence, DNA diagnostics, Antibiotic resistance, Infectious diseases, Bioinformatics, Metagenomics, Microbial biotechnology, Microbial source tracking, Water quality
Research field
Medical microbiology, Microbiology, Medical biotechnology
Field of Research code, Australian and New Zealand Standard Research Classification (ANZSRC), 2020
Qualifications
- Ph.D (University of Pretoria)
- MMedSci (Medical Microbiology) (University of Pretoria)
- Post Graduate Certificate in Higher Education (University of Queensland)
- BSc(Agric) Microbiology (University of Pretoria)
Professional memberships and associations
- FASM
Teaching
Teaching discipline: Cell and Molecular Biosciences
Publications
- Huygens, F., Bamber, J., Nimmo, G., Munckhof, W., Schooneveldt, J., Harrison, B., McMahon, J. & Giffard, P. (2006). Staphylococcus Aureus Genotyping Using Novel Real-Time PCR Formats. Journal of Clinical Microbiology, 44(10), 3712–3719. https://eprints.qut.edu.au/7673
- Huygens, F., Stephens, A., Nimmo, G. & Giffard, P. (2004). mecA Locus Diversity in Methicillin-Resistant Staphylococcus Aureus Isolates in Brisbane, Australia, and the Development of a Novel Diagnostic Procedure for the Western Samoan Phage Pattern Clone. Journal of Clinical Microbiology, 42(5), 1947–1955. https://eprints.qut.edu.au/7676
- Stephens, A., Bamber, J., Giffard, P. & Huygens, F. (2008). High-resolution melting analysis of the spa Repeat region of Staphylococcus aureus. Clinical Chemistry, 54(2), 432–436. https://eprints.qut.edu.au/224409
- Stephens, A., Huygens, F., Bamber, J., Price, E., Nimmo, G., Schooneveldt, J., Munckhof, W. & Giffard, P. (2006). Methicillin-Resistance Staphylococcus Aureus Genotyping using a Small Set of Polymorphisms. Journal of Medical Microbiology, 55(1), 43–51. https://eprints.qut.edu.au/7678
- Costello, M. & Huygens, F. (2011). Diversity of community acquired MRSA carrying the PVL gene in Queensland and New South Wales, Australia. European Journal of Clinical Microbiology and Infectious Diseases, 30(10), 1163–1167. https://eprints.qut.edu.au/41424
- Rayner, R., Savill, J., Hafner, L. & Huygens, F. (2015). Modified MLVA for genotyping Queensland invasive Streptococcus pneumoniae. PLoS One, 4(10), 1–15. https://eprints.qut.edu.au/83976
- Rayner, R., Savill, J., Hafner, L. & Huygens, F. (2015). Genotyping Streptococcus pneumoniae. Future Microbiology, 10(4), 653–664. https://eprints.qut.edu.au/83975
- Kleinschmidt, S., Huygens, F., Faoagali, J., Rathnayake, I. & Hafner, L. (2015). Staphylococcus epidermidis as a cause of bacteremia. Future Microbiology, 10(11), 1859–1879. https://eprints.qut.edu.au/91237
- Rathnayake, I., Hargreaves, M. & Huygens, F. (2011). Genotyping of Enterococcus faecalis and Enterococcus faecium isolates by use of a set of eight single nucleotide polymorphisms. Journal of Clinical Microbiology, 49(1), 367–372. https://eprints.qut.edu.au/39076
- Sheludchenko, M., Huygens, F. & Hargreaves, M. (2011). Human-specific E. coli single nucleotide polymorphism (SNP) genotypes detected in a South East Queensland waterway, Australia. Environmental Science & Technology, 45(24), 10331–10336. https://eprints.qut.edu.au/47141
QUT ePrints
For more publications by Flavia, explore their research in QUT ePrints (our digital repository).
Filter publications:
A complete list of publications is available at: https://www.qut.edu.au/about/our-people/academic-profiles/f.huygens
Supervision
Completed supervisions (Doctorate)
- Molecular Characterisation of Hospital and Community Associated Methicillin-Resistant Staphylococcus aureus Isolates in Queensland (2025)
- The Effect of Diurnal Rhythm on the Gut Metabolome in Inflammation and Diabetes (2024)
- Genomic and virulence studies of Vibrio cholerae O1 and Non-O1, Non-O139 in Queensland Australia (2023)
- The interactions between probiotic bacteria and respiratory viruses within the epithelium of the upper respiratory tract (2023)
- Rapid Detection of Safe and Efficient Gene Editing Targets Across Entire Genomes (2022)
- Understanding STEC Epidemiology and Predominance of O157:H-negative in Australia: Genetic Characterisation and Virulence Assessment of STEC Isolates (2022)
- Understanding the Diabetic Foot Ulcer Microbiome and its Impact on Wound Severity (2021)
- Diversity of Arthropod-Borne Viruses and Implications for Wolbachia-Based Biocontrol (2019)
- Molecular Characterisation of Bacteraemia and Contamination Isolates of Staphylococcus epidermidis Isolated from Patient Blood Cultures (2018)
- An Investigation of the Impact of Bacterial Diversity, Pathogenic Determinants and Biofilms on Chronic Wounds (2017)
Completed supervisions (Masters by Research)
- Variation of surface polysaccharides in the ST25 clonal lineage of Acinetobacter baumannii (2021)
- A Prostate Cell Line Model of Persistent Zika Virus Infection (2019)
- An Investigation of the Genotypes for Mycobacterium intracellulare in Queensland (2018)
- Molecular Analysis of Mycobacterium Kansasii from Human and Potable Water Specimens (2017)
- Structural Characterisation of the Term Placenta: Maternal Obesity and Gestational Diabetes Mellitus (2017)
The supervisions listed above are only a selection.