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Histological analysis of explanted pelvic meshes

Pelvic mesh implantation is a common surgical procedure employed to treat stress urinary incontinence, rectal prolapse and pelvic organ prolapse. Data from the Therapeutic Goods Administration (TGA) showed that 151,000 meshes have been implanted in Australia since 1998 and 3.7 million world-wide between 2005 and 2013. However, the use of pelvic meshes can cause complications such as erosion, infection, pain and discomfort, which sometimes require further surgery. With high complication rates the FDA recently issued 2 warnings against the use …

Study level
Vacation research experience scheme
Faculty
Faculty of Engineering
School
School of Mechanical, Medical and Process Engineering
Research centre(s)
Centre for Biomedical Technologies

Investigation of host tissue response to synthetic pelvic meshes in patients with complications

Pelvic organ prolapse (POP) is a prevalent disease affecting 37% of asymptomatic women. Pelvic mesh implantation is a common surgical procedure employed to treat stress urinary incontinence, rectal prolapse and pelvic organ prolapse. However, the use of pelvic meshes can cause complications such as erosion, infection, pain and discomfort, which sometimes require further surgery. In Australia, in November 2017, the TGA banned transvaginal mesh for prolapse. Currently, women with complications from their pelvic mesh may opt to have them surgically …

Study level
Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)
Centre for Biomedical Technologies

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