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Patient specific modelling of the human shoulder joint complex

Modern advanced manufacturing techniques have the potential to revolutionise the patient-specific orthopaedic implant space. Many of the existing orthopaedic joint replacements offer a modular design, allowing surgeons to select the size of each component to suit their patient.However in some joints, for example the shoulder, the conditions that lead to a shoulder replacement (osteoarthritis of the shoulder and rotator cuff tears) also create anatomical anomalies that are challenging to correct with generic implant shapes.The advent of titanium 3D printing provides …

Study level
Honours, Vacation research experience scheme
Faculty
Science and Engineering Faculty
Lead unit
School of Mechanical, Medical and Process Engineering

Intravascular optical coherence tomography imaging for vulnerable atheroma detection

The sudden rupture of vulnerable atherosclerotic plaques and subsequent thrombosis formations are responsible for most acute vascular syndromes, such as myocardial infarction and stroke. Many victims who are apparently healthy die suddenly with no prior symptoms.Such deaths could be prevented through surgery or alternative medical therapy, if vulnerable plaques were identified earlier in their natural progression.While intravascular methods have been developed to visualize various features of vulnerable plaques, there is no single technique that can accurately predict plaque rupture in …

Study level
PhD, Master of Philosophy, Honours, Vacation research experience scheme
Faculty
Science and Engineering Faculty
Lead unit
School of Mechanical, Medical and Process Engineering

Optimising bone shape with memory networks

Bone is a dynamic tissue that optimises its shape to the mechanical loads that it carries. Bone mass is accrued where loads are high, and reduced where loads are low. This adaptation of bone tissue to mechanical loads is well known and observed in many instances. However, what serves as a reference mechanical state in this shape optimisation remains largely unknown.

Study level
PhD, Master of Philosophy, Honours, Vacation research experience scheme
Faculty
Science and Engineering Faculty
Lead unit
School of Mathematical Sciences

Finite element methods for modelling the deformation of polymers

The finite element method (FEM) is by now a well-established and widely accepted approach for modelling the deformation of linearly elastic materials.In this project we will explore which FEM approach and constitutive laws may be applicable for modelling polymers, which have more deformation behaviour than a simple elastic material. Our long-term goal is to be able to accurately model the deformation of polymer bioscaffolds fabricated with the novel melt-electrowriting (MEW) additive manufacturing process. …

Study level
Master of Philosophy, Honours, Vacation research experience scheme
Faculty
Science and Engineering Faculty
Lead unit
School of Mathematical Sciences

Computational methods for multi-scale structural optimisation

Structural optimisation is a powerful computational methodology for finding high-performing designs for structural components or material architectures. For example, what periodic scaffold would provide the highest possible stiffness for its weight?Solving such a problem computationally requires an understanding of the relevant equations required to model the physical properties of interest, as well as efficient implementation of a range of numerical methods including finite elements, finite differences and optimisation.With recent developments in 3D printing technologies it is now possible to manufacture …

Study level
PhD, Master of Philosophy, Honours, Vacation research experience scheme
Faculty
Science and Engineering Faculty
Lead unit
School of Mathematical Sciences

Developing models of failure for porous materials

The field of fracture mechanics effectively models failure of sharp flaws (e.g., cracks). However, when modelling porous materials we'd like to develop more of an understanding of how stresses are concentrated around smooth flaws in the material (i.e., rounded pores).In this project we'll start to build such an understanding, starting from simple U shaped notches.

Study level
Honours, Vacation research experience scheme
Faculty
Science and Engineering Faculty
Lead unit
School of Mathematical Sciences

3D-printed soft robotics to simulate popliteal artery endovascular treatment

Peripheral artery disease (PAD) is one of the most frequent cardiovascular diseases, affecting over 200 million people at an annual cost of $21 billion.PAD cases are predominately (80%) located within the popliteal artery, a highly flexible vessel behind the knee joint which twists, extends, and bends during standing, walking, and sitting.As a result, active or sedentary lifestyles play an important role in altering the biomechanics leading to popliteal diseases.Furthermore, surgical treatments within the popliteal artery have been inconsistent, with a …

Study level
PhD, Master of Philosophy, Honours, Vacation research experience scheme
Faculty
Science and Engineering Faculty
Lead unit
School of Mechanical, Medical and Process Engineering

A biofabrication surgical referral suite to predict intracranial aneurysm rupture

Intracranial aneurysms are bulging, weak areas of an artery that supply blood to the brain which are relatively common. While most aneurysms do not show symptoms, 1% spontaneously rupture which can be fatal or leave the survivor with permanent disabilities. This catastrophic outcome has motivated surgeons to operate on approximately 30% of aneurysms despite their rate of complications arising and cost of operation.The impact of aneurysm morphology on blood flow shear stress and rupture could educate surgical decision-making and better …

Study level
PhD, Master of Philosophy, Honours, Vacation research experience scheme
Faculty
Science and Engineering Faculty
Lead unit
School of Mechanical, Medical and Process Engineering

Materials discovery and design from quantum mechanics-based computational approaches

Understanding novel physics in nanoscale materials is critical for the development of modern electronics technology.However, such delicate materials are difficult to manipulate and characterize experimentally because of their tiny size. This raises the conundrum of how to proceed forward quickly with exploration and subsequently design of properties.In principle, materials properties are determined by the electronic structure. Quantum mechanics based computational approaches are able to address fundamental electronic, optical and magnetic properties in such materials.This provides a powerful complement to the …

Study level
PhD, Master of Philosophy, Honours
Faculty
Science and Engineering Faculty
Lead unit
School of Chemistry and Physics

Targeting Fibrosis: Identification of novel natural compounds to modulate collagen expression

Liver disease is a huge and increasing burden on society; it can be due to a number of different reasons including excessive alcohol consumption, viral infections, and non-alcoholic liver disease. Each of these causes may have a different molecular pathway of developing the disease pathology, but one common feature is there is an injury or insult to the liver. This injury then results in activation of the wound healing process; when this healing process goes awry liver disease can develop, …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
Lead unit
School of Biomedical Sciences

Characteristics of 'successful' engagement: evaluating approaches to communication engagement in business or local government

Engagement offers organisations an ethical mechanism to respond to organisational-stakeholder power imbalances and enhance corporate governance in the interests of wider society. Stakeholder demands for authentic engagement may address stakeholder-held views of perceived organisation-stakeholder power deficits. Challenges exist, however, for corporate managers to provide relevant information and become responsive to the diverse stakeholder interests (Johnston, 2016). This study seeks to understand, document and theorise the characteristics of 'successful' engagement.Required skills and experienceThis project is ideal for a candidate with strong …

Study level
PhD, Master of Philosophy
Faculty
QUT Business School
Lead unit
School of Advertising, Marketing and Public Relations

Controlling soft matter materials at the nano-level – how to construct materials whose mechanical properties can be remotely adjusted

Nature is an expert at developing high-performance materials which combine properties like high toughness, stiffness, and low weight.Some well-known examples include:woodbonespider silk.In this project we aim to mimic the structure and properties of another, less known natural high-performance material: nacre.Additionally, we want to introduce a light-adaptive control mechanism. This will enable a controlled transformation of physical and mechanical properties in real-time.To achieve adaptable properties, a control mechanism on the molecular level is required, featuring several distinct functional plateaus.It is proposed …

Study level
PhD, Master of Philosophy, Honours, Vacation research experience scheme
Faculty
Science and Engineering Faculty
Lead unit
School of Chemistry and Physics

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