Found 4 matching student topics
Displaying 1–4 of 4 results
Optimising bone shape with memory networks
Bone is a dynamic tissue that optimises its shape to the mechanical loads that it carries. Bone mass is accrued where loads are high, and reduced where loads are low. This adaptation of bone tissue to mechanical loads is well known and observed in many instances. However, what serves as a reference mechanical state in this shape optimisation remains largely unknown.
- Study level
- PhD, Master of Philosophy, Honours, Vacation research experience scheme
- Faculty
- Science and Engineering Faculty
- Lead unit
- School of Mathematical Sciences
Computational modelling of liquid marbles
Liquid marbles are liquid droplets coated with super-hydrophobic particles. They possess interesting properties such as the ability to contain liquid content without wetting surfaces and enhanced elasticity.Numerous experimental studies on liquid marbles and their properties have already been reported in the literature. For example, novel microfluidic applications, miniature bioreactors and gas sensing mechanisms. Despite plenty of experimental work, there is limited computational modelling investigations of liquid marbles represented in literature.A successful numerical model would be able to derive new insights …
- Study level
- PhD, Master of Philosophy, Honours, Vacation research experience scheme
- Faculty
- Science and Engineering Faculty
- Lead unit
- School of Mechanical, Medical and Process Engineering
Topological control over cell behaviour for robust additive tissue biomanufacturing
Hospital departments are adopting medical imaging, modelling, and 3D printing to automate personalised implant manufacture and avoid malpractice related to surgical handcrafting. Although several 3D printed implants are approved for medical use, their therapeutic value remains limited as acellular devices with coarse resolution. The ability to print scaffold implants with cell microenvironment precision has been achieved using melt electrowriting (MEW), an emerging technique frequently applied to produce cell culture scaffolds.In contemporary MEW studies, the effect of materials or pore sizes …
- Study level
- PhD, Master of Philosophy, Honours, Vacation research experience scheme
- Faculty
- Science and Engineering Faculty
- Lead unit
- School of Mechanical, Medical and Process Engineering
Mathematical modelling of the mechanobiology during plaque growth
Plaque growth is a chronic inflammatory response induced by the interactions between vascular endothelial cells, lipids, monocytes/macrophages, vascular smooth muscle cells and platelets in the arteries. The mechanism involves interactions between the activities of cellular and acellular components in plaque microenvironment. Experimental studies have revealed the contributing roles of many different biological factors and processes, such as:lipid depositioninflammationangiogenesishaemorrhage.Due to the difficulties in experimental measurement and visualisation of the multiscale process, and the complex nature of the local environment, these complex …
- Study level
- PhD, Master of Philosophy, Honours, Vacation research experience scheme
- Faculty
- Science and Engineering Faculty
- Lead unit
- School of Mechanical, Medical and Process Engineering