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Male chlamydia infections: the key role of macrophages in testicular dissemination and disrupted spermatogenesis

Chlamydia trachomatis is an obligate intracellular, bacterial pathogen. Chlamydia infections of the human reproductive tract affect approximately 131 million people globally each year. The major concern of chlamydial infections is its ability to cause infertility in both men and women, by damaging the upper reproductive tracts.The testis is a tightly regulated, immune-privileged, environment. The key cell types (Macrophages, Leydig, Sertoli and Germ cells) each play a specific role in regulating spermatogenesis (production of sperm).Our lab has found that chlamydial infections …

Study level
Vacation research experience scheme
Faculty of Health
School of Biomedical Sciences
Research centre(s)

Centre for Immunology and Infection Control

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