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Impact of cytomegalovirus on human responses to malaria parasites

The lifelong viral infection cytomegalovirus (CMV) has broad influence on the human immune system. Some studies in young adults have suggested that these CMV mediated changes can enhance responsiveness to vaccination and infection. How CMV infection impacts immunity to malaria parasites is unknown.This project will leverage previous experimental human malaria infection trials to investigate whether CMV infection modifies innate and adaptive immune responses following malaria.AimsInvestigate whether CMV infection impacts innate immune responses (monocytes, DCs, gamma delta cells and NK cells) …

Study level
Faculty of Health
School of Biomedical Sciences

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