QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.

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Found 2 matching student topics

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Identification of novel melanoma biomarkers using exosomes

Tumour cells excrete exosomes, membrane vesicles (30-150 nm diameter) that encapsulate and transport proteins, metabolites and genetic material. They mediate intercellular communication within the tumor microenvironment, metastasis formation via circulation, and development of drug resistance. Circulating tumor-derived exosomes can be isolated from blood patients as a non-invasive liquid biopsy.The chemical composition and overall properties of the exosomal membranes are expected to be similar to those of parent cell membranes and to modulate blood circulation time, and uptake and targeting of …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

QIMR02 - Targeting breast cancer and metastasis by oligonucleotide therapeutics with lipid nanoparticle (LNP) delivery system

Cancer is the second leading cause of death worldwide. The major cause of cancer-related mortality (~90%) is due to metastasis. Breast cancer (BC) is the most commonly diagnosed cancer among women. Of the 10,000 Australians that live with metastatic breast cancer only 32% are alive after 5-years (relative survival-rate).While current cancer treatments mostly focus on targeting the primary tumours, the treatment or prevention of metastasis continues to have limited success. We have shown genetic inhibition of Cep55 reduces cancer progression …

Study level
Vacation research experience scheme
Faculty
Faculty of Health
School
School of Biomedical Sciences

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