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Histological analysis of explanted pelvic meshes

Pelvic mesh implantation is a common surgical procedure employed to treat stress urinary incontinence, rectal prolapse and pelvic organ prolapse. Data from the Therapeutic Goods Administration (TGA) showed that 151,000 meshes have been implanted in Australia since 1998 and 3.7 million world-wide between 2005 and 2013. However, the use of pelvic meshes can cause complications such as erosion, infection, pain and discomfort, which sometimes require further surgery. With high complication rates the FDA recently issued 2 warnings against the use …

Study level
Vacation research experience scheme
Faculty
Faculty of Engineering
School
School of Mechanical, Medical and Process Engineering
Research centre(s)
Centre for Biomedical Technologies

Development of methods to analyse cells in 3D bioengineered human tumour models

Over the past few decades, cancer mortality has risen more than 2.6-folds in Australia, mandating novel research to study and understand the mechanisms of cancer biology. Recent advancements in technology have led to development of novel scaffold-based, bioengineered 3D tumour models that recapitulate the complex, in vivo cancer microenvironment better than the conventional 2D monolayer cultures.Specifically, tumour cells encapsulated in hydrogel systems are widely used as effective 3D tumour models because of how closely they mimic the native tissue extracellular …

Study level
Vacation research experience scheme
Faculty
Faculty of Engineering
School
School of Mechanical, Medical and Process Engineering
Research centre(s)
Centre for Biomedical Technologies

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