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Found 3 matching student topics

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Immune regulation in tissue formation

Immune cells are essential in maintaining tissue homeostasis and function.This project will will work on the interaction between immune cells and tissue forming cells aiming to regulate the processes of tissue repair and regeneration.

Study level
PhD
Faculty
Science and Engineering Faculty
School
School of Mechanical, Medical and Process Engineering
Research centre(s)

Biofabrication and tissue engineering

Biofabrication and tissue engineering seeks to create 3D scaffolds containing cells to heal defected tissue.People suffering from tissue loss often have to have autografts (where tissue is transferred from one part of their body to the other, leading to 2 sites of surgery and associated morbididy)We use scanning modelling and 3D printing to create 3D scaffolds that can perfectly fit the defect site and may contain cells or growth factors to stimulate new tissue formation - this circumvents the need …

Study level
Vacation research experience scheme
Faculty
Science and Engineering Faculty
School
School of Mechanical, Medical and Process Engineering
Research centre(s)
Centre for Biomedical Technologies

Investigating DNA repair mechanisms in aging adult stem cells

When we age the DNA repair systems of our cells become down regulated. This results in reduced DNA repair capacity, enhanced rates of mutation load and may lead to the development of chronic aging-associated diseases including osteoporosis, Alzheimer's and cancer(1). So it is no surprise that genome instability and stem cell exhaustion, which also strongly correlates with the accumulation of DNA damage, are considered hallmarks of aging(2). However, we still lack a clear understanding on how the decrease in DNA …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)

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