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Characterising a DNA repair protein as an anti-cancer therapeutic target and diagnostic marker in brain cancer

Cancer is the single biggest clinical problem facing the world and will account for half of all global deaths by 2030. Even though there have been significant advances in immunotherapy, we are still unable to cure most cancers. New therapeutic targets, individualised to patient needs, must be identified and validated in order to improve cancer outcomes.Brain cancer causes more deaths in people under the age of 40 than any other cancer and more deaths in children than any other disease. …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)
Centre for Genomics and Personalised Health

Optimising delivery of a novel nose-to-brain treatment for brain cancer

Glioblastoma multiforme (GBM) is an aggressive brain cancer with no curative treatment and poor prognosis. One of the biggest challenges with treating GBM is the inability of treatment to cross the blood-brain barrier resulting in poor drug distribution in the brain. Fortunately, scientists have recently developed a novel nose-to-brain delivery system that uses nanoparticles loaded with a chemotherapy drug called paclitaxel. Initial treatment investigations in vivo are showing significant promise in reducing and controlling the tumour burden. While exciting, before …

Study level
Master of Philosophy, Honours, Vacation research experience scheme
Faculty
Faculty of Science
School
School of Mathematical Sciences

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